PDB: 61 件ウェブページステータス検索Chemie searchBIRD

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2P5I	Crystal structure of protein BH3822 from Bacillus halodurans, a member of the biotin/lipoate A/B protein ligase family 分子名称: BH3822 protein 著者 Sugadev, R, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2007-03-15 公開日 2007-03-27 最終更新日 2021-02-03 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Crystal structure of a hypothetical protein from Bacillus halodurans: Pfam-PF03099 To be Published
6CK0	Crystal Structure of Biotin Acetyl Coenzyme A Carboxylase Synthetase from Helicobacter pylori with bound Biotinylated ATP 分子名称: 1,2-ETHANEDIOL, 5'-O-[(S)-({5-[(2R,3aS,4S,6aR)-2-hydroxyhexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}oxy){[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]adenosine, Biotin acetyl coenzyme A carboxylase synthetase, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-02-27 公開日 2018-04-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structure of Biotin Acetyl Coenzyme A Carboxylase Synthetase from Helicobacter pylori with bound Biotinylated ATP to be published
6JHU	Crystal Structure Of Biotin Protein Ligase From Leishmania Major in complex with Biotinyl-5-AMP 分子名称: BIOTINYL-5-AMP, Biotin/lipoate protein ligase-like protein, SULFATE ION 著者 Rajak, M, Patel, A, Sundd, M. 登録日 2019-02-19 公開日 2020-04-08 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Leishmania major biotin protein ligase forms a unique cross-handshake dimer Acta Crystallogr.,Sect.D, 77, 2021
7DBS	Crystal Structure Of Biotin Protein Ligase From Leishmania Major in complex with Biotin 分子名称: BIOTIN, Biotin/lipoate protein ligase-like protein 著者 Rajak, M, Sundd, M. 登録日 2020-10-21 公開日 2021-04-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Leishmania major biotin protein ligase forms a unique cross-handshake dimer. Acta Crystallogr D Struct Biol, 77, 2021
3L2Z	Crystal structure of hydrated Biotin Protein Ligase from M. tuberculosis 分子名称: BirA bifunctional protein 著者 Gupta, V, Gupta, R.K, Khare, G, Salunke, D.M, Tyagi, A.K. 登録日 2009-12-16 公開日 2010-03-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural ordering of disordered ligand-binding loops of biotin protein ligase into active conformations as a consequence of dehydration. Plos One, 5, 2010
3L1A	Structural ordering of disordered ligand binding loops of biotin protein ligase into active conformations as a consequence of dehydration 分子名称: BirA bifunctional protein 著者 Gupta, V. 登録日 2009-12-11 公開日 2010-03-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Structural ordering of disordered ligand-binding loops of biotin protein ligase into active conformations as a consequence of dehydration. Plos One, 5, 2010
3RUX	Crystal structure of biotin-protein ligase BirA from Mycobacterium tuberculosis in complex with an acylsulfamide bisubstrate inhibitor 分子名称: 5'-deoxy-5'-[({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}sulfamoyl)amino]adenosine, BirA bifunctional protein 著者 Geders, T.W, Finzel, B.C. 登録日 2011-05-05 公開日 2011-12-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Bisubstrate Adenylation Inhibitors of Biotin Protein Ligase from Mycobacterium tuberculosis. Chem.Biol., 18, 2011
4WF2	Structure of E. coli BirA G142A bound to biotinol-5'-AMP 分子名称: ((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHYL 5-((3AS,4S,6AR)-2-OXO-HEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL)PENTYL HYDROGEN PHOSPHATE, Bifunctional ligase/repressor BirA 著者 Eginton, C, Beckett, D, Wade, H. 登録日 2014-09-11 公開日 2014-10-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Allosteric Coupling via Distant Disorder-to-Order Transitions. J.Mol.Biol., 427, 2015
1HXD	CRYSTAL STRUCTURE OF E. COLI BIOTIN REPRESSOR WITH BOUND BIOTIN 分子名称: BIOTIN, BIRA BIFUNCTIONAL PROTEIN 著者 Kwon, K, Streaker, E.D, Ruparelia, S, Beckett, D. 登録日 2001-01-12 公開日 2001-05-30 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Corepressor-induced organization and assembly of the biotin repressor: a model for allosteric activation of a transcriptional regulator. Proc.Natl.Acad.Sci.USA, 98, 2001
2ZGW	Crystal Structure Of Biotin Protein Ligase From Pyrococcus Horikoshii Complexed with Adenosine and Biotin, Mutations R48A and K111A 分子名称: ADENOSINE, BIOTIN, biotin--[acetyl-CoA-carboxylase] ligase 著者 Bagautdinov, B, Matsuura, Y, Bagautdinova, S, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2008-01-28 公開日 2008-02-05 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Protein biotinylation visualized by a complex structure of biotin protein ligase with a substrate J.Biol.Chem., 283, 2008
4OP0	Crystal structure of biotin protein ligase (RV3279C) of Mycobacterium tuberculosis, complexed with biotinyl-5'-AMP 分子名称: BIOTINYL-5-AMP, BirA bifunctional protein, SULFATE ION 著者 Ma, Q, Wilmanns, M, Akhter, Y. 登録日 2014-02-04 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Active site conformational changes upon reaction intermediate biotinyl-5'-AMP binding in biotin protein ligase from Mycobacterium tuberculosis. Protein Sci., 23, 2014
6NDL	Crystal structure of Staphylococcus aureus biotin protein ligase in complex with a sulfonamide inhibitor 分子名称: 1-[4-(6-aminopurin-9-yl)butylsulfamoyl]-3-[4-[(4~{S})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]butyl]urea, Biotin Protein Ligase, GLYCEROL 著者 Marshall, A.C, Polyak, S.W, Bruning, J.B, Lee, K. 登録日 2018-12-13 公開日 2019-12-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Sulfonamide-Based Inhibitors of Biotin Protein Ligase as New Antibiotic Leads. Acs Chem.Biol., 14, 2019
1BIA	THE E. COLI BIOTIN HOLOENZYME SYNTHETASE(SLASH)BIO REPRESSOR CRYSTAL STRUCTURE DELINEATES THE BIOTIN AND DNA-BINDING DOMAINS 分子名称: BirA BIFUNCTIONAL PROTEIN 著者 Wilson, K.P, Shewchuk, L.M, Matthews, B.W. 登録日 1992-07-06 公開日 1993-10-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Escherichia coli biotin holoenzyme synthetase/bio repressor crystal structure delineates the biotin- and DNA-binding domains. Proc.Natl.Acad.Sci.USA, 89, 1992
1BIB	THE E. COLI BIOTIN HOLOENZYME SYNTHETASE(SLASH)BIO REPRESSOR CRYSTAL STRUCTURE DELINEATES THE BIOTIN AND DNA-BINDING DOMAINS 分子名称: BIOTIN, BIR A 著者 Wilson, K.P, Shewchuk, L.M, Matthews, B.W. 登録日 1992-07-06 公開日 1993-10-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Escherichia coli biotin holoenzyme synthetase/bio repressor crystal structure delineates the biotin- and DNA-binding domains. Proc.Natl.Acad.Sci.USA, 89, 1992
6ORU	Crystal structure of Bira from S. aureus in complex with a acylsulfamide analogue of biotinyl-5'-AMP 分子名称: Bifunctional ligase/repressor BirA, N-{[4-(6-amino-9H-purin-9-yl)butyl]sulfamoyl}-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide 著者 Wilce, M.C.J, Cini, D. 登録日 2019-05-01 公開日 2020-07-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.392 Å) 主引用文献 Enhancing the stability of the sulfonamide linker of BPL inhibitors To Be Published
2EWN	Ecoli Biotin Repressor with co-repressor analog 分子名称: ((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHYL 5-((3AS,4S,6AR)-2-OXO-HEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL)PENTYL HYDROGEN PHOSPHATE, BirA bifunctional protein 著者 Wood, Z.A, Weaver, L.H, Matthews, B.W. 登録日 2005-11-04 公開日 2006-02-21 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Co-repressor Induced Order and Biotin Repressor Dimerization: A Case for Divergent Followed by Convergent Evolution. J.Mol.Biol., 357, 2006
8ENI	Crystal structure of Staphylococcus aureus biotin protein ligase in complex with inhibitor 分子名称: 3-[4-(5-fluoro-4-{5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentyl}-1H-1,2,3-triazol-1-yl)butyl]-5-methyl-1,3-benzoxazol-2(3H)-one, Bifunctional ligase/repressor BirA 著者 Wilce, M.C.J, Cini, D.A. 登録日 2022-09-30 公開日 2022-11-30 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Halogenation of Biotin Protein Ligase Inhibitors Improves Whole Cell Activity against Staphylococcus aureus. ACS Infect Dis, 4, 2018
2HNI	Crystal Structure Of Biotin Protein Ligase From Pyrococcus Horikoshii OT3, K111A mutation 分子名称: 235aa long hypothetical biotin-[acetyl-CoA-carboxylase] ligase, ACETIC ACID 著者 Bagautdinov, B, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-07-13 公開日 2007-01-13 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Ligand Structures Of Biotin Protein Ligase From Pyrococcus Horikoshii OT3 To be Published
3EFS	Biotin protein ligase from Aquifex aeolicus in complex with biotin and ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, BIOTIN, Biotin [acetyl-CoA-carboxylase] ligase, ... 著者 Tron, C.M, McNae, I.W, Walkinshaw, M.D, Baxter, R.L, Campopiano, D.J. 登録日 2008-09-10 公開日 2009-06-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural and functional studies of the biotin protein ligase from Aquifex aeolicus reveal a critical role for a conserved residue in target specificity. J.Mol.Biol., 387, 2009
8F8U	Bifunctional ligase/repressor BirA from Klebsiella pneumoniae (Domain Swapped Dimer) 分子名称: Bifunctional ligase/repressor BirA, IMIDAZOLE 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2022-11-22 公開日 2022-11-30 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Bifunctional ligase/repressor BirA from Klebsiella pneumoniae (Domain Swapped Dimer) To be published
8FI3	Bifunctional ligase/repressor BirA from Klebsiella pneumoniae complexed with biotin (Domain Swapped Dimer) 分子名称: BIOTIN, Bifunctional ligase/repressor BirA 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2022-12-15 公開日 2022-12-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Bifunctional ligase/repressor BirA from Klebsiella pneumoniae complexed with biotin (Domain Swapped Dimer) To be published
3EFR	Biotin protein ligase R40G mutant from Aquifex aeolicus in complex with biotin 分子名称: BIOTIN, Biotin [acetyl-CoA-carboxylase] ligase, SULFATE ION 著者 Tron, C.M, McNae, I.W, Walkinshaw, M.D, Baxter, R.L, Campopiano, D.J. 登録日 2008-09-10 公開日 2009-06-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural and functional studies of the biotin protein ligase from Aquifex aeolicus reveal a critical role for a conserved residue in target specificity. J.Mol.Biol., 387, 2009
3FJP	Apo structure of Biotin protein ligase from Aquifex aeolicus 分子名称: Biotin [acetyl-CoA-carboxylase] ligase, SULFATE ION 著者 McNae, I.W, Tron, C.M, Baxter, R.L, Walkinshaw, M.D, Campopiano, D.J. 登録日 2008-12-15 公開日 2009-06-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural and functional studies of the biotin protein ligase from Aquifex aeolicus reveal a critical role for a conserved residue in target specificity. J.Mol.Biol., 387, 2009
2FYK	Crystal Structure Of Biotin Protein Ligase From Pyrococcus Horikoshii OT3 in complex with ADP and Biotin 分子名称: ADENOSINE-5'-DIPHOSPHATE, BIOTIN, biotin--protein ligase 著者 Bagautdinov, B, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-02-08 公開日 2006-08-08 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Ligand Structures Of Biotin Protein Ligase From Pyrococcus Horikoshii Ot3 To be Published
1WNL	Crystal Structure Of Biotin-(Acetyl-CoA-Carboxylase) ligase From Pyrococcus Horikoshii Ot3 in complex with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, biotin--[acetyl-CoA-carboxylase] ligase 著者 Bagautdinov, B, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-08-05 公開日 2005-08-16 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal Structures of Biotin Protein Ligase from Pyrococcus horikoshii OT3 and its Complexes: Structural Basis of Biotin Activation J.Mol.Biol., 353, 2005

 

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