PDB: 15 件ウェブページステータス検索Chemie searchBIRD

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6MVD	Crystal structure of Lecithin:cholesterol acyltransferase (LCAT) in complex with isopropyl dodec-11-enylfluorophosphonate (IDFP) and a small molecule activator 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-{4-[(4R)-4-hydroxy-6-oxo-4-(trifluoromethyl)-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-b]pyridin-3-yl]piperidin-1-yl}-4-(trifluoromethyl)pyridine-3-carbonitrile, NICKEL (II) ION, ... 著者 Manthei, K.A, Chang, L, Tesmer, J.J.G. 登録日 2018-10-25 公開日 2018-12-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Molecular basis for activation of lecithin:cholesterol acyltransferase by a compound that increases HDL cholesterol. Elife, 7, 2018
7X2P	Legionella pneumophila effector RavL 分子名称: Putative lipase 著者 Zheng, J, Lu, Z, Chen, S. 登録日 2022-02-26 公開日 2023-03-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Legionella pneumophila effector RavL To Be Published
5BV7	Crystal structure of human LCAT (L4F, N5D) in complex with Fab of an agonistic antibody 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 27C3 heavy chain, 27C3 light chain, ... 著者 Piper, D.E, Romanow, W.G, Thibault, S.T, Walker, N.P.C. 登録日 2015-06-04 公開日 2015-12-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Agonistic Human Antibodies Binding to Lecithin-Cholesterol Acyltransferase Modulate High Density Lipoprotein Metabolism. J.Biol.Chem., 291, 2016
5TXF	Crystal structure of Lecithin:cholesterol acyltransferase (LCAT) in a closed conformation 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Phosphatidylcholine-sterol acyltransferase, ... 著者 Manthei, K.A, Glukhova, A, Tesmer, J.J.G. 登録日 2016-11-16 公開日 2017-10-25 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 A retractable lid in lecithin:cholesterol acyltransferase provides a structural mechanism for activation by apolipoprotein A-I. J. Biol. Chem., 292, 2017
6MTW	Lysosomal Phospholipase A2 in complex with Zinc 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Group XV phospholipase A2, ... 著者 Bouley, R, Tesmer, J.J.G. 登録日 2018-10-22 公開日 2019-03-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.999 Å) 主引用文献 Structural Basis of Lysosomal Phospholipase A2Inhibition by Zn2. Biochemistry, 58, 2019
4XX1	Low resolution structure of LCAT in complex with Fab1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab1 heavy chain, Fab1 light chain, ... 著者 Piper, D.E, Walker, N.P.C, Romanow, W.G, Thibault, S.T. 登録日 2015-01-29 公開日 2015-07-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 The high-resolution crystal structure of human LCAT. J.Lipid Res., 56, 2015
4XWG	Crystal Structure of LCAT (C31Y) in complex with Fab1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab1 Heavy Chain, Fab1 Light Chain, ... 著者 Piper, D.E, Walker, N.P.C, Romanow, W.G, Thibault, S.T. 登録日 2015-01-28 公開日 2015-07-29 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 The high-resolution crystal structure of human LCAT. J.Lipid Res., 56, 2015
4X90	Crystal structure of Lysosomal Phospholipase A2 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Glukhova, A, Tesmer, J.J.G. 登録日 2014-12-11 公開日 2015-03-11 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Structure and function of lysosomal phospholipase A2 and lecithin:cholesterol acyltransferase. Nat Commun, 6, 2015
4X94	Crystal structure of Lysosomal Phospholipase A2 crystallized in the presence of methyl arachidonyl fluorophosphonate (hexagonal form) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Group XV phospholipase A2, ... 著者 Glukhova, A, Tesmer, J.J.G. 登録日 2014-12-11 公開日 2015-03-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure and function of lysosomal phospholipase A2 and lecithin:cholesterol acyltransferase. Nat Commun, 6, 2015
4X91	Crystal structure of Lysosomal Phospholipase A2 in complex with Isopropyl dodec-11-enylfluorophosphonate (IDFP) 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Glukhova, A, Tesmer, J.J.G. 登録日 2014-12-11 公開日 2015-03-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure and function of lysosomal phospholipase A2 and lecithin:cholesterol acyltransferase. Nat Commun, 6, 2015
4X93	Crystal structure of Lysosomal Phospholipase A2 crystallized in the presence of methyl arachidonyl fluorophosphonate (tetragonal form) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Glukhova, A, Tesmer, J.J.G. 登録日 2014-12-11 公開日 2015-03-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure and function of lysosomal phospholipase A2 and lecithin:cholesterol acyltransferase. Nat Commun, 6, 2015
4X92	Crystal structure of Lysosomal Phospholipase A2-S165A 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Group XV phospholipase A2 著者 Glukhova, A, Tesmer, J.J.G. 登録日 2014-12-11 公開日 2015-03-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure and function of lysosomal phospholipase A2 and lecithin:cholesterol acyltransferase. Nat Commun, 6, 2015
4X96	Low resolution crystal structure of Lecithin:Cholesterol Acyltransferase (LCAT; residues 21-397) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Phosphatidylcholine-sterol acyltransferase, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Glukhova, A, Tesmer, J.J.G. 登録日 2014-12-11 公開日 2015-03-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (8.69 Å) 主引用文献 Structure and function of lysosomal phospholipase A2 and lecithin:cholesterol acyltransferase. Nat Commun, 6, 2015
4X95	Crystal structure of fully glycosylated Lysosomal Phospholipase A2 in complex with methyl arachidonyl fluorophosphonate (MAFP) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Group XV phospholipase A2, METHYL ARACHIDONYL FLUOROPHOSPHONATE, ... 著者 Glukhova, A, Tesmer, J.J.G. 登録日 2014-12-11 公開日 2015-03-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.08 Å) 主引用文献 Structure and function of lysosomal phospholipase A2 and lecithin:cholesterol acyltransferase. Nat Commun, 6, 2015
4X97	Crystal structure of Lysosomal Phospholipase A2 in complex with methyl arachidonyl fluorophosphonate (MAFP) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ... 著者 Glukhova, A, Tesmer, J.J.G. 登録日 2014-12-11 公開日 2015-03-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structure and function of lysosomal phospholipase A2 and lecithin:cholesterol acyltransferase. Nat Commun, 6, 2015