8SGZ
 
 | | Leishmania tarentolae propionyl-CoA carboxylase (alpha-6-beta-6) | | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-coa carboxylase beta chain, putative, ... | | 著者 | Lee, J.K.J, Liu, Y.T, Hu, J.J, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H. | | 登録日 | 2023-04-13 | | 公開日 | 2023-05-17 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | CryoEM reveals oligomeric isomers of a multienzyme complex and assembly mechanics.
J Struct Biol X, 7, 2023
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8SGY
 | | Leishmania tarentolae propionyl-CoA carboxylase (alpha-5-beta-6) | | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-coa carboxylase beta chain, putative, ... | | 著者 | Lee, J.K.J, Liu, Y.T, Hu, J.J, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H. | | 登録日 | 2023-04-13 | | 公開日 | 2023-05-17 | | 実験手法 | ELECTRON MICROSCOPY (8.62 Å) | | 主引用文献 | CryoEM reveals oligomeric isomers of a multienzyme complex and assembly mechanics.
J Struct Biol X, 7, 2023
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8SGX
 | | Leishmania tarentolae propionyl-CoA carboxylase (alpha-4-beta-6) | | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-coa carboxylase beta chain, putative, ... | | 著者 | Lee, J.K.J, Liu, Y.T, Hu, J.J, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H. | | 登録日 | 2023-04-13 | | 公開日 | 2023-05-17 | | 実験手法 | ELECTRON MICROSCOPY (10.3 Å) | | 主引用文献 | CryoEM reveals oligomeric isomers of a multienzyme complex and assembly mechanics.
J Struct Biol X, 7, 2023
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8PN8
 | | Engineered glycolyl-CoA carboxylase (L100N variant) with bound CoA | | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Propionyl-CoA carboxylase alpha subunit, ... | | 著者 | Zarzycki, J, Marchal, D.G, Schulz, L, Prinz, S, Erb, T.J. | | 登録日 | 2023-06-30 | | 公開日 | 2023-11-29 | | 最終更新日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (2.31 Å) | | 主引用文献 | Machine Learning-Supported Enzyme Engineering toward Improved CO 2 -Fixation of Glycolyl-CoA Carboxylase.
Acs Synth Biol, 12, 2023
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8PN7
 | | Engineered glycolyl-CoA carboxylase (G20R variant) with bound CoA | | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Propionyl-CoA carboxylase alpha subunit, ... | | 著者 | Zarzycki, J, Marchal, D.G, Schulz, L, Prinz, S, Erb, T.J. | | 登録日 | 2023-06-30 | | 公開日 | 2023-11-29 | | 最終更新日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (2.03 Å) | | 主引用文献 | Machine Learning-Supported Enzyme Engineering toward Improved CO 2 -Fixation of Glycolyl-CoA Carboxylase.
Acs Synth Biol, 12, 2023
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8F41
 | | 3-methylcrotonyl-CoA carboxylase in filament, alpha-subunit centered | | 分子名称: | 3-methylcrotonyl-CoA carboxylase, alpha-subunit, beta-subunit, ... | | 著者 | Hu, J.J, Lee, J.K.J, Liu, Y.T, Yu, C, Huang, L, Afasizheva, I, Afasizhev, R, Zhou, Z.H. | | 登録日 | 2022-11-10 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-01-18 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Discovery, structure, and function of filamentous 3-methylcrotonyl-CoA carboxylase.
Structure, 31, 2023
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8F3D
 | | 3-methylcrotonyl-CoA carboxylase in filament, beta-subunit centered | | 分子名称: | 3-methylcrotonyl-CoA carboxylase alpha-subunit, 3-methylcrotonyl-CoA carboxylase beta-subunit, 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL | | 著者 | Hu, J.J, Lee, J.K.J, Liu, Y.T, Yu, C, Huang, L, Afasizheva, I, Afasizhev, R, Zhou, Z.H. | | 登録日 | 2022-11-09 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-01-18 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Discovery, structure, and function of filamentous 3-methylcrotonyl-CoA carboxylase.
Structure, 31, 2023
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7YBU
 | | Human propionyl-coenzyme A carboxylase | | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-CoA carboxylase alpha chain, mitochondrial, ... | | 著者 | Su, J.Y, Liu, D.S. | | 登録日 | 2022-06-29 | | 公開日 | 2023-07-05 | | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | | 主引用文献 | Human propionyl-coenzyme A carboxylase
To Be Published
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7W5U
 | | Acetyl-CoA Carboxylase-AccB | | 分子名称: | Acetyl-CoA carboxylase complex, beta-chain, GLYCEROL, ... | | 著者 | Ali, I, Zheng, J. | | 登録日 | 2021-11-30 | | 公開日 | 2022-04-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Crystal structure of Acetyl-CoA carboxylase (AccB) from Streptomyces antibioticus and insights into the substrate-binding through in silico mutagenesis and biophysical investigations.
Comput Biol Med, 145, 2022
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6YBQ
 | | Engineered glycolyl-CoA carboxylase (quintuple mutant) with bound CoA | | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Propionyl-CoA carboxylase alpha subunit, ... | | 著者 | Schuller, J.M, Schuller, S.K, Zarzycki, J, Scheffen, M, Marchal, D.M, Erb, T.J. | | 登録日 | 2020-03-17 | | 公開日 | 2020-10-28 | | 最終更新日 | 2021-05-12 | | 実験手法 | ELECTRON MICROSCOPY (1.96 Å) | | 主引用文献 | A new-to-nature carboxylation module to improve natural and synthetic CO2 fixation
Nat Catal, 2021
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6YBP
 | | Propionyl-CoA carboxylase of Methylorubrum extorquens with bound CoA | | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Propionyl-CoA carboxylase alpha subunit, ... | | 著者 | Schuller, J.M, Schuller, S.K, Zarzycki, J, Scheffen, M, Marchal, D.M, Erb, T.J. | | 登録日 | 2020-03-17 | | 公開日 | 2020-10-28 | | 最終更新日 | 2021-05-12 | | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | | 主引用文献 | A new-to-nature carboxylation module to improve natural and synthetic CO2 fixation
Nat Catal, 2021
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6TZV
 | | Crystal Structure of the carboxyltransferase subunit of ACC (AccD6) in complex with inhibitor Phenyl-Cyclodiaone from Mycobacterium tuberculosis | | 分子名称: | 4'-[(6-chloro-1,3-benzothiazol-2-yl)oxy]-6-hydroxy-4,4-dimethyl-4,5-dihydro[1,1'-biphenyl]-2(3H)-one, Probable propionyl-CoA carboxylase beta chain 6 | | 著者 | Reddy, M.C.M, Zhou, N, Sacchettini, J, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2019-08-13 | | 公開日 | 2020-08-19 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.388 Å) | | 主引用文献 | Novel herbicidal derivatives that inhibit carboxyltransferase subunit of the acetyl-CoA carboxylase in Mycobacterium tuberculosis
To Be Published
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6PRW
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6PK2
 | | CRYSTAL STRUCTURE OF THE CARBOXYLTRANSFERASE SUBUNIT OF ACC (ACCD6) IN COMPLEX WITH INHIBITOR QUIZALOFOP-P derivative FROM MYCOBACTERIUM TUBERCULOSIS | | 分子名称: | 2-{4-[(6-fluoro-1,3-benzothiazol-2-yl)oxy]-2-hydroxyphenyl}-N-methylacetamide, Propionyl-CoA carboxylase subunit beta | | 著者 | Reddy, M.C.M, Nian, Z, Michele, T.C.B, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2019-06-28 | | 公開日 | 2020-07-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.402 Å) | | 主引用文献 | Elucidating the Inhibition and specificity of binding of
herbicidal aryloxyphenoxypropionates derivatives to Mycobacterium tuberculosis carboxyltransferase
domain of acetyl-coenzyme A(AccD6).
To Be Published
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6P7U
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6G2I
 | | Filament of acetyl-CoA carboxylase and BRCT domains of BRCA1 (ACC-BRCT) at 5.9 A resolution | | 分子名称: | Acetyl-CoA carboxylase 1, Breast cancer type 1 susceptibility protein | | 著者 | Hunkeler, M, Hagmann, A, Stuttfeld, E, Chami, M, Stahlberg, H, Maier, T. | | 登録日 | 2018-03-23 | | 公開日 | 2018-06-13 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | | 主引用文献 | Structural basis for regulation of human acetyl-CoA carboxylase.
Nature, 558, 2018
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6G2H
 | | Filament of acetyl-CoA carboxylase and BRCT domains of BRCA1 (ACC-BRCT) core at 4.6 A resolution | | 分子名称: | Acetyl-CoA carboxylase 1 | | 著者 | Hunkeler, M, Hagmann, A, Stuttfeld, E, Chami, M, Stahlberg, H, Maier, T. | | 登録日 | 2018-03-23 | | 公開日 | 2018-06-13 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Structural basis for regulation of human acetyl-CoA carboxylase.
Nature, 558, 2018
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6G2D
 | | Citrate-induced acetyl-CoA carboxylase (ACC-Cit) filament at 5.4 A resolution | | 分子名称: | Acetyl-CoA carboxylase 1 | | 著者 | Hunkeler, M, Hagmann, A, Stuttfeld, E, Chami, M, Stahlberg, H, Maier, T. | | 登録日 | 2018-03-23 | | 公開日 | 2018-06-13 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (5.4 Å) | | 主引用文献 | Structural basis for regulation of human acetyl-CoA carboxylase.
Nature, 558, 2018
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5VJ1
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5VIT
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5VIP
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5KDR
 | | The crystal structure of carboxyltransferase from Staphylococcus Aureus bound to the antimicrobial agent moiramide B. | | 分子名称: | 1,2-ETHANEDIOL, Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ... | | 著者 | Silvers, M.A, Pakhomova, S, Neau, D, Silvers, W.C, Anzalone, N, Taylor, C.M, Waldrop, G.L. | | 登録日 | 2016-06-08 | | 公開日 | 2016-08-10 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structure of Carboxyltransferase from Staphylococcus aureus Bound to the Antibacterial Agent Moiramide B.
Biochemistry, 55, 2016
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5INI
 | | Structural basis for acyl-CoA carboxylase-mediated assembly of unusual polyketide synthase extender units incorporated into the stambomycin antibiotics | | 分子名称: | HEXANOYL-COENZYME A, Putative carboxyl transferase | | 著者 | Valentic, T.R, Ray, L, Miyazawa, T, Withall, D.M, Song, L, Milligan, J.C, Osada, H, Tsai, S.C, Challis, G.L. | | 登録日 | 2016-03-07 | | 公開日 | 2016-12-28 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | A crotonyl-CoA reductase-carboxylase independent pathway for assembly of unusual alkylmalonyl-CoA polyketide synthase extender units.
Nat Commun, 7, 2016
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5ING
 | | A crotonyl-CoA reductase-carboxylase independent pathway for assembly of unusual alkylmalonyl-CoA polyketide synthase extender unit | | 分子名称: | Putative carboxyl transferase | | 著者 | Valentic, T.R, Ray, L, Miyazawa, T, Song, L, Withall, D.M, Milligan, J.C, Takahashi, S, Osada, H, Tsai, S.C, Challis, G.L. | | 登録日 | 2016-03-07 | | 公開日 | 2016-12-28 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | A crotonyl-CoA reductase-carboxylase independent pathway for assembly of unusual alkylmalonyl-CoA polyketide synthase extender units.
Nat Commun, 7, 2016
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5INF
 | | Structural basis for acyl-CoA carboxylase-mediated assembly of unusual polyketide synthase extender units incorporated into the stambomycin antibiotics | | 分子名称: | Carboxyl transferase, HEXANOYL-COENZYME A | | 著者 | Valentic, T.R, Ray, L, Miyazawa, T, Withall, D.M, Song, L, Osada, H, Tsai, S.C, Challis, G.L. | | 登録日 | 2016-03-07 | | 公開日 | 2016-12-28 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.751 Å) | | 主引用文献 | A crotonyl-CoA reductase-carboxylase independent pathway for assembly of unusual alkylmalonyl-CoA polyketide synthase extender units.
Nat Commun, 7, 2016
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