5FRC
| Structure of urate oxidase prepared by the 'soak-and-freeze' method under 42 bar of oxygen pressure | 分子名称: | 8-AZAXANTHINE, OXYGEN MOLECULE, SODIUM ION, ... | 著者 | Lafumat, B, Mueller-Dieckmann, C, Colloc'h, N, Prange, T, Royant, A, van der Linden, P, Carpentier, P. | 登録日 | 2015-12-16 | 公開日 | 2016-10-26 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.443 Å) | 主引用文献 | Gas-Sensitive Biological Crystals Processed in Pressurized Oxygen and Krypton Atmospheres: Deciphering Gas Channels in Proteins Using a Novel `Soak-and-Freeze' Methodology. J.Appl.Crystallogr., 49, 2016
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5M98
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4XFP
| Crystal Structure of Highly Active Mutant of Bacillus sp. TB-90 Urate Oxidase | 分子名称: | 8-AZAXANTHINE, CHLORIDE ION, SULFATE ION, ... | 著者 | Hibi, T, Hayashi, Y, Kawamura, A, Itoh, T. | 登録日 | 2014-12-28 | 公開日 | 2016-01-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Glycine Substitution of Surface Proline 287 Involves Entropic Enhancement of Bacillus sp. TB-90 Uricase Activity To be published
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4MB8
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1J2G
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7A0L
| Joint neutron/X-ray room temperature structure of perdeuterated Aspergillus flavus urate oxidase in complex with the 8-azaxanthine inhibitor and catalytic water bound in the peroxo hole | 分子名称: | 8-AZAXANTHINE, SODIUM ION, Uricase | 著者 | McGregor, L, Bui, S, Blakeley, M.P, Steiner, R.A. | 登録日 | 2020-08-09 | 公開日 | 2020-12-09 | 最終更新日 | 2024-05-01 | 実験手法 | NEUTRON DIFFRACTION (1.33 Å), X-RAY DIFFRACTION | 主引用文献 | Joint neutron/X-ray crystal structure of a mechanistically relevant complex of perdeuterated urate oxidase and simulations provide insight into the hydration step of catalysis. Iucrj, 8, 2021
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6OE8
| The crystal structure of hyper-thermostable AgUricase mutant K12C/E286C | 分子名称: | MALONATE ION, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, ... | 著者 | Shi, Y, Wang, T, Zhou, X.E, Liu, Q, Jiang, Y, Xu, H.E. | 登録日 | 2019-03-27 | 公開日 | 2019-08-21 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structure-based design of a hyperthermostable AgUricase for hyperuricemia and gout therapy. Acta Pharmacol.Sin., 40, 2019
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5AYJ
| Hyperthermostable mutant of Bacillus sp. TB-90 Urate Oxidase - R298C | 分子名称: | 9-METHYL URIC ACID, HEXAETHYLENE GLYCOL, SULFATE ION, ... | 著者 | Hibi, T, Kume, A, Kawamura, A, Itoh, T, Nishiya, Y. | 登録日 | 2015-08-21 | 公開日 | 2016-01-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Hyperstabilization of Tetrameric Bacillus sp. TB-90 Urate Oxidase by Introducing Disulfide Bonds through Structural Plasticity Biochemistry, 55, 2016
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5LL1
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3GKO
| Crystal structure of urate oxydase using surfactant Poloxamer 188 as a New Crystallizing Agent | 分子名称: | 8-AZAXANTHINE, POTASSIUM ION, Uricase | 著者 | Delfosse, V, Giffard, M, Sciara, G, Bonnete, F, Mayer, C. | 登録日 | 2009-03-11 | 公開日 | 2010-02-23 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Surfactant Poloxamer 188 as a New Crystallizing Agent for Urate Oxidase Cryst.Growth Des., 9, 2009
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2PES
| Urate Oxidase in complex with tris-dipicolinate Lutetium | 分子名称: | 8-AZAXANTHINE, LUTETIUM (III) ION, PYRIDINE-2,6-DICARBOXYLIC ACID, ... | 著者 | Pompidor, G, Vicat, J, Kahn, R. | 登録日 | 2007-04-03 | 公開日 | 2008-04-22 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | A dipicolinate lanthanide complex for solving protein structures using anomalous diffraction. Acta Crystallogr.,Sect.D, 66, 2010
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3WLV
| Thermostable urate oxidase from Bacillus sp. TB-90 | 分子名称: | 8-AZAXANTHINE, CHLORIDE ION, POTASSIUM ION, ... | 著者 | Hibi, T, Hayashi, Y, Itoh, T. | 登録日 | 2013-11-14 | 公開日 | 2014-06-18 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.747 Å) | 主引用文献 | Intersubunit salt bridges with a sulfate anion control subunit dissociation and thermal stabilization of Bacillus sp. TB-90 urate oxidase. Biochemistry, 53, 2014
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7F2V
| Urate oxidase from Thermobispora bispora in apo form | 分子名称: | DIMETHYL SULFOXIDE, SULFATE ION, Uricase | 著者 | Chiu, Y.C, Hsu, T.S, Huang, C.Y, Hsu, C.H. | 登録日 | 2021-06-14 | 公開日 | 2022-05-04 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural and biochemical insights into a hyperthermostable urate oxidase from Thermobispora bispora for hyperuricemia and gout therapy. Int.J.Biol.Macromol., 188, 2021
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7F2W
| TbUox in complex with uric acid | 分子名称: | URIC ACID, Uricase | 著者 | Chiu, Y.C, Hsu, T.S, Huang, C.Y, Hsu, C.H. | 登録日 | 2021-06-14 | 公開日 | 2022-05-04 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Structural and biochemical insights into a hyperthermostable urate oxidase from Thermobispora bispora for hyperuricemia and gout therapy. Int.J.Biol.Macromol., 188, 2021
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4R99
| Crystal structure of a uricase from Bacillus fastidious | 分子名称: | SULFATE ION, Uricase | 著者 | Feng, J, Wang, L, Liu, H.B, Liu, L, Liao, F. | 登録日 | 2014-09-03 | 公開日 | 2015-05-27 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of Bacillus fastidious uricase reveals an unexpected folding of the C-terminus residues crucial for thermostability under physiological conditions. Appl.Microbiol.Biotechnol., 99, 2015
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4R8X
| Crystal structure of a uricase from Bacillus fastidious | 分子名称: | Uricase | 著者 | Feng, J, Wang, L, Liu, H.B, Liu, L, Liao, F. | 登録日 | 2014-09-03 | 公開日 | 2015-05-27 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.401 Å) | 主引用文献 | Crystal structure of Bacillus fastidious uricase reveals an unexpected folding of the C-terminus residues crucial for thermostability under physiological conditions. Appl.Microbiol.Biotechnol., 99, 2015
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6RGM
| urate oxidase under 130 bar of krypton | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 8-AZAXANTHINE, ACETATE ION, ... | 著者 | Prange, T, Colloc'h, N, Carpentier, P. | 登録日 | 2019-04-17 | 公開日 | 2020-05-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Comparative study of the effects of high hydrostatic pressure per se and high argon pressure on urate oxidase ligand stabilization Acta Cryst. D, 78, 2022
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6RGT
| Crystal structure of the cofactor-free Aspergillus flavus urate oxidase T57A variant anaerobically complexed with 9-methyl uric acid | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 9-METHYL URIC ACID, ... | 著者 | Bui, S, Lowden, S.R.J, Steiner, R.A. | 登録日 | 2019-04-17 | 公開日 | 2020-05-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of the cofactor-free Aspergillus flavus urate oxidase T57A variant anaerobically complexed with 9-methyl uric acid To Be Published
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4CW2
| Crystal structure of cofactor-free urate oxidase in complex with the 5-peroxo derivative of 9-metyl uric acid (X-ray dose, 2.5 kGy) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, (5S)-5-(dioxidanyl)-9-methyl-7H-purine-2,6,8-trione, URICASE | 著者 | Bui, S, Steiner, R.A. | 登録日 | 2014-04-01 | 公開日 | 2014-10-29 | 最終更新日 | 2018-02-21 | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | 主引用文献 | Direct evidence for a peroxide intermediate and a reactive enzyme-substrate-dioxygen configuration in a cofactor-free oxidase. Angew. Chem. Int. Ed. Engl., 53, 2014
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4CW3
| Crystal structure of cofactor-free urate oxidase in complex with the 5-peroxo derivative of 9-metyl uric acid (X-ray dose, 665 kGy) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, (5S)-5-(dioxidanyl)-9-methyl-7H-purine-2,6,8-trione, 9-METHYL URIC ACID, ... | 著者 | Bui, S, Steiner, R.A. | 登録日 | 2014-04-01 | 公開日 | 2014-10-29 | 最終更新日 | 2018-02-21 | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | 主引用文献 | Direct evidence for a peroxide intermediate and a reactive enzyme-substrate-dioxygen configuration in a cofactor-free oxidase. Angew. Chem. Int. Ed. Engl., 53, 2014
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4CW0
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4CW6
| Crystal structure of cofactor-free urate oxidase in complex with the 5-peroxo derivative of 9-metyl uric acid (X-ray dose, 92 kGy) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, (5S)-5-(dioxidanyl)-9-methyl-7H-purine-2,6,8-trione, 9-METHYL URIC ACID, ... | 著者 | Bui, S, Steiner, R.A. | 登録日 | 2014-04-01 | 公開日 | 2014-10-29 | 最終更新日 | 2018-02-21 | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | 主引用文献 | Direct evidence for a peroxide intermediate and a reactive enzyme-substrate-dioxygen configuration in a cofactor-free oxidase. Angew. Chem. Int. Ed. Engl., 53, 2014
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7P0D
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7P0G
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7P0C
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