Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7G7J

Crystal Structure of rat Autotaxin in complex with 4-[(3aR,6aR)-2-[(E)-3-[2-[(5-methyltetrazol-2-yl)methyl]-4-(trifluoromethyl)phenyl]prop-2-enoyl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carbonyl]-3-fluorobenzenesulfonamide, i.e. SMILES [C@@H]12CN(C(=O)c3c(cc(cc3)S(=O)(=O)N)F)C[C@H]1CN(C2)C(=O)/C=C/c1ccc(cc1CN1N=NC(=N1)C)C(F)(F)F with IC50=0.00194649 microM

Resources

File format		File name (file size)
PDBx/mmCIF		7g7j.cif.gz Display(198.01 KB) 7g7j.cif
PDBx/mmJSON	all	7g7j.json.gz Display (Tree)(133.74 KB) 7g7j.json
	no-atom	7g7j-noatom.json.gz Display (Header)(27.57 KB) 7g7j-noatom.json
	add only	7g7j-plus.json.gz Display(1.94 KB) 7g7j-plus.json
PDBML	all	7g7j.xml.gz Display(265.09 KB) 7g7j.xml
	no-atom	7g7j-noatom.xml.gz Display(52.53 KB) 7g7j-noatom.xml
	ext-atom	7g7j-extatom.xml.gz Display(160.67 KB) 7g7j-extatom.xml
pdb_nextgen	all	pdb_00007g7j_xyz-enrich.cif.gz Display(217.13 KB) pdb_00007g7j_xyz-enrich.cif
	no-atom	pdb_00007g7j_xyz-no-atom-enrich.xml.gz Display(62.65 KB) pdb_00007g7j_xyz-no-atom-enrich.xml
	ng-only	7g7j-plus.json.gz Display(4.71 KB) 7g7j-plus.json
PDB		pdb7g7j.ent.gz Display(151.05 KB) pdb7g7j.ent
RDF		7g7j.rdf.gz Visualize(147.72 KB) 7g7j.rdf
Structure factors		r7g7jsf.ent.gz Display(12.53 MB) r7g7jsf.ent
Biological unit (mmCIF format)		7g7j-assembly1.cif.gz Display(183.55 KB) 7g7j-assembly1.cif (A) *author and software defined assembly, 1 molecule(s) (monomeric)
Biological unit (PDB format)		7g7j.pdb1.gz Display(144.04 KB) 7g7j.pdb1 (A) *author and software defined assembly, 1 molecule(s) (monomeric)
Validation reports	PDF	7g7j_validation.pdf.gz Display(1.14 MB) 7g7j_validation.pdf
	PDF-full	7g7j_full_validation.pdf.gz Display(1.15 MB) 7g7j_full_validation.pdf
	mmCIF	7g7j_validation.cif.gz Display(55.67 KB) 7g7j_validation.cif
	XML	7g7j_validation.xml.gz Display(39.83 KB) 7g7j_validation.xml
	PNG	7g7j_multipercentile_validation.png.gz Display(166.29 KB) 7g7j_multipercentile_validation.png
	SVG	7g7j_multipercentile_validation.svg.gz Display(958.00 B) 7g7j_multipercentile_validation.svg
EDMap	2fo-fc (PDBx/mmCIF)	7g7j_validation_2fo-fc_map_coef.cif.gz Display(1.20 MB) 7g7j_validation_2fo-fc_map_coef.cif
	fo-fc (PDBx/mmCIF)	7g7j_validation_fo-fc_map_coef.cif.gz Display(1.20 MB) 7g7j_validation_fo-fc_map_coef.cif
	2fo-fc (MTZ)	7g7j_validation_2fo-fc_map_coef.mtz Visualize(1.96 MB)
	fo-fc (MTZ)	7g7j_validation_fo-fc_map_coef.mtz Visualize(1.96 MB)

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)