Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7G6O

Crystal Structure of rat Autotaxin in complex with 6-[(3aR,6aR)-5-[5-cyclopropyl-6-(oxan-4-yloxy)pyridine-3-carbonyl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-2-carbonyl]pyridine-3-sulfonamide, i.e. SMILES N1(C[C@@H]2[C@@H](C1)CN(C2)C(=O)c1cc(c(nc1)OC1CCOCC1)C1CC1)C(=O)c1ncc(cc1)S(=O)(=O)N with IC50=0.0360867 microM

Resources

File format		File name (file size)
PDBx/mmCIF		7g6o.cif.gz Display(192.26 KB) 7g6o.cif
PDBx/mmJSON	all	7g6o.json.gz Display (Tree)(127.69 KB) 7g6o.json
	no-atom	7g6o-noatom.json.gz Display (Header)(25.86 KB) 7g6o-noatom.json
	add only	7g6o-plus.json.gz Display(1.93 KB) 7g6o-plus.json
PDBML	all	7g6o.xml.gz Display(257.54 KB) 7g6o.xml
	no-atom	7g6o-noatom.xml.gz Display(50.83 KB) 7g6o-noatom.xml
	ext-atom	7g6o-extatom.xml.gz Display(155.54 KB) 7g6o-extatom.xml
pdb_nextgen	all	pdb_00007g6o_xyz-enrich.cif.gz Display(210.78 KB) pdb_00007g6o_xyz-enrich.cif
	no-atom	pdb_00007g6o_xyz-no-atom-enrich.xml.gz Display(60.96 KB) pdb_00007g6o_xyz-no-atom-enrich.xml
	ng-only	7g6o-plus.json.gz Display(4.71 KB) 7g6o-plus.json
PDB		pdb7g6o.ent.gz Display(146.24 KB) pdb7g6o.ent
RDF		7g6o.rdf.gz Visualize(145.11 KB) 7g6o.rdf
Structure factors		r7g6osf.ent.gz Display(8.41 MB) r7g6osf.ent
Biological unit (mmCIF format)		7g6o-assembly1.cif.gz Display(177.88 KB) 7g6o-assembly1.cif (A) *author and software defined assembly, 1 molecule(s) (monomeric)
Biological unit (PDB format)		7g6o.pdb1.gz Display(139.43 KB) 7g6o.pdb1 (A) *author and software defined assembly, 1 molecule(s) (monomeric)
Validation reports	PDF	7g6o_validation.pdf.gz Display(1.11 MB) 7g6o_validation.pdf
	PDF-full	7g6o_full_validation.pdf.gz Display(1.12 MB) 7g6o_full_validation.pdf
	mmCIF	7g6o_validation.cif.gz Display(52.96 KB) 7g6o_validation.cif
	XML	7g6o_validation.xml.gz Display(38.72 KB) 7g6o_validation.xml
	PNG	7g6o_multipercentile_validation.png.gz Display(171.38 KB) 7g6o_multipercentile_validation.png
	SVG	7g6o_multipercentile_validation.svg.gz Display(978.00 B) 7g6o_multipercentile_validation.svg
EDMap	2fo-fc (PDBx/mmCIF)	7g6o_validation_2fo-fc_map_coef.cif.gz Display(695.90 KB) 7g6o_validation_2fo-fc_map_coef.cif
	fo-fc (PDBx/mmCIF)	7g6o_validation_fo-fc_map_coef.cif.gz Display(693.78 KB) 7g6o_validation_fo-fc_map_coef.cif
	2fo-fc (MTZ)	7g6o_validation_2fo-fc_map_coef.mtz Visualize(1.12 MB)
	fo-fc (MTZ)	7g6o_validation_fo-fc_map_coef.mtz Visualize(1.12 MB)

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)