Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7G5U

Crystal Structure of rat Autotaxin in complex with [(3aS,6aS)-5-[4-(2,2,2-trifluoroethoxy)quinoline-2-carbonyl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-2-yl]-(1H-benzotriazol-5-yl)methanone, i.e. SMILES N1(C[C@@H]2[C@@H](C1)CN(C2)C(=O)c1nc2c(c(c1)OCC(F)(F)F)cccc2)C(=O)c1ccc2c(c1)N=NN2 with IC50=0.0117937 microM

Resources

File format		File name (file size)
PDBx/mmCIF		7g5u.cif.gz Display(194.09 KB) 7g5u.cif
PDBx/mmJSON	all	7g5u.json.gz Display (Tree)(128.97 KB) 7g5u.json
	no-atom	7g5u-noatom.json.gz Display (Header)(25.98 KB) 7g5u-noatom.json
	add only	7g5u-plus.json.gz Display(1.90 KB) 7g5u-plus.json
PDBML	all	7g5u.xml.gz Display(259.13 KB) 7g5u.xml
	no-atom	7g5u-noatom.xml.gz Display(51.07 KB) 7g5u-noatom.xml
	ext-atom	7g5u-extatom.xml.gz Display(157.12 KB) 7g5u-extatom.xml
pdb_nextgen	all	pdb_00007g5u_xyz-enrich.cif.gz Display(212.67 KB) pdb_00007g5u_xyz-enrich.cif
	no-atom	pdb_00007g5u_xyz-no-atom-enrich.xml.gz Display(61.22 KB) pdb_00007g5u_xyz-no-atom-enrich.xml
	ng-only	7g5u-plus.json.gz Display(4.71 KB) 7g5u-plus.json
PDB		pdb7g5u.ent.gz Display(147.49 KB) pdb7g5u.ent
RDF		7g5u.rdf.gz Visualize(145.05 KB) 7g5u.rdf
Structure factors		r7g5usf.ent.gz Display(6.85 MB) r7g5usf.ent
Biological unit (mmCIF format)		7g5u-assembly1.cif.gz Display(180.09 KB) 7g5u-assembly1.cif (A) *author and software defined assembly, 1 molecule(s) (monomeric)
Biological unit (PDB format)		7g5u.pdb1.gz Display(140.79 KB) 7g5u.pdb1 (A) *author and software defined assembly, 1 molecule(s) (monomeric)
Validation reports	PDF	7g5u_validation.pdf.gz Display(1.12 MB) 7g5u_validation.pdf
	PDF-full	7g5u_full_validation.pdf.gz Display(1.13 MB) 7g5u_full_validation.pdf
	mmCIF	7g5u_validation.cif.gz Display(52.81 KB) 7g5u_validation.cif
	XML	7g5u_validation.xml.gz Display(38.19 KB) 7g5u_validation.xml
	PNG	7g5u_multipercentile_validation.png.gz Display(174.12 KB) 7g5u_multipercentile_validation.png
	SVG	7g5u_multipercentile_validation.svg.gz Display(976.00 B) 7g5u_multipercentile_validation.svg
EDMap	2fo-fc (PDBx/mmCIF)	7g5u_validation_2fo-fc_map_coef.cif.gz Display(828.40 KB) 7g5u_validation_2fo-fc_map_coef.cif
	fo-fc (PDBx/mmCIF)	7g5u_validation_fo-fc_map_coef.cif.gz Display(830.00 KB) 7g5u_validation_fo-fc_map_coef.cif
	2fo-fc (MTZ)	7g5u_validation_2fo-fc_map_coef.mtz Visualize(1.33 MB)
	fo-fc (MTZ)	7g5u_validation_fo-fc_map_coef.mtz Visualize(1.33 MB)

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)