Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7G5Q

Crystal Structure of rat Autotaxin in complex with (3S)-3-[[2-[2-methoxy-6-[[methyl-[(4-methyl-1,3-thiazol-2-yl)methyl]amino]methyl]phenoxy]acetyl]amino]-N-methyl-3-[3-(trifluoromethyl)phenyl]propanamide, i.e. SMILES c1cc(cc(c1)C(F)(F)F)[C@H](CC(=O)NC)NC(=O)COc1c(cccc1CN(CC1=NC(=CS1)C)C)OC with IC50=0.814833 microM

Resources

File format		File name (file size)
PDBx/mmCIF		7g5q.cif.gz Display(206.74 KB) 7g5q.cif
PDBx/mmJSON	all	7g5q.json.gz Display (Tree)(141.37 KB) 7g5q.json
	no-atom	7g5q-noatom.json.gz Display (Header)(29.89 KB) 7g5q-noatom.json
	add only	7g5q-plus.json.gz Display(1.90 KB) 7g5q-plus.json
PDBML	all	7g5q.xml.gz Display(277.68 KB) 7g5q.xml
	no-atom	7g5q-noatom.xml.gz Display(55.64 KB) 7g5q-noatom.xml
	ext-atom	7g5q-extatom.xml.gz Display(167.48 KB) 7g5q-extatom.xml
pdb_nextgen	all	pdb_00007g5q_xyz-enrich.cif.gz Display(226.68 KB) pdb_00007g5q_xyz-enrich.cif
	no-atom	pdb_00007g5q_xyz-no-atom-enrich.xml.gz Display(65.58 KB) pdb_00007g5q_xyz-no-atom-enrich.xml
	ng-only	7g5q-plus.json.gz Display(4.71 KB) 7g5q-plus.json
PDB		pdb7g5q.ent.gz Display(157.35 KB) pdb7g5q.ent
RDF		7g5q.rdf.gz Visualize(153.41 KB) 7g5q.rdf
Structure factors		r7g5qsf.ent.gz Display(14.74 MB) r7g5qsf.ent
Biological unit (mmCIF format)		7g5q-assembly1.cif.gz Display(192.04 KB) 7g5q-assembly1.cif (A) *author and software defined assembly, 1 molecule(s) (monomeric)
Biological unit (PDB format)		7g5q.pdb1.gz Display(149.98 KB) 7g5q.pdb1 (A) *author and software defined assembly, 1 molecule(s) (monomeric)
Validation reports	PDF	7g5q_validation.pdf.gz Display(1.08 MB) 7g5q_validation.pdf
	PDF-full	7g5q_full_validation.pdf.gz Display(1.09 MB) 7g5q_full_validation.pdf
	mmCIF	7g5q_validation.cif.gz Display(63.48 KB) 7g5q_validation.cif
	XML	7g5q_validation.xml.gz Display(43.71 KB) 7g5q_validation.xml
	PNG	7g5q_multipercentile_validation.png.gz Display(165.62 KB) 7g5q_multipercentile_validation.png
	SVG	7g5q_multipercentile_validation.svg.gz Display(946.00 B) 7g5q_multipercentile_validation.svg
EDMap	2fo-fc (PDBx/mmCIF)	7g5q_validation_2fo-fc_map_coef.cif.gz Display(1.60 MB) 7g5q_validation_2fo-fc_map_coef.cif
	fo-fc (PDBx/mmCIF)	7g5q_validation_fo-fc_map_coef.cif.gz Display(1.60 MB) 7g5q_validation_fo-fc_map_coef.cif
	2fo-fc (MTZ)	7g5q_validation_2fo-fc_map_coef.mtz Visualize(2.61 MB)
	fo-fc (MTZ)	7g5q_validation_fo-fc_map_coef.mtz Visualize(2.61 MB)

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)