Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7G5M

Crystal Structure of rat Autotaxin in complex with rac-(E)-1-[rac-(3aR,8aS)-2-(1,4,6,7-tetrahydrotriazolo[4,5-c]pyridine-5-carbonyl)-1,3,3a,4,5,7,8,8a-octahydropyrrolo[3,4-d]azepin-6-yl]-3-[4-(trifluoromethoxy)phenyl]prop-2-en-1-one, i.e. SMILES C1C[C@@H]2[C@H](CCN1C(=O)/C=C/c1ccc(cc1)OC(F)(F)F)CN(C2)C(=O)N1CCC2=C(C1)N=NN2 with IC50=0.0280543 microM

Resources

File format		File name (file size)
PDBx/mmCIF		7g5m.cif.gz Display(193.38 KB) 7g5m.cif
PDBx/mmJSON	all	7g5m.json.gz Display (Tree)(128.30 KB) 7g5m.json
	no-atom	7g5m-noatom.json.gz Display (Header)(25.78 KB) 7g5m-noatom.json
	add only	7g5m-plus.json.gz Display(1.95 KB) 7g5m-plus.json
PDBML	all	7g5m.xml.gz Display(258.69 KB) 7g5m.xml
	no-atom	7g5m-noatom.xml.gz Display(50.71 KB) 7g5m-noatom.xml
	ext-atom	7g5m-extatom.xml.gz Display(156.69 KB) 7g5m-extatom.xml
pdb_nextgen	all	pdb_00007g5m_xyz-enrich.cif.gz Display(211.97 KB) pdb_00007g5m_xyz-enrich.cif
	no-atom	pdb_00007g5m_xyz-no-atom-enrich.xml.gz Display(60.89 KB) pdb_00007g5m_xyz-no-atom-enrich.xml
	ng-only	7g5m-plus.json.gz Display(4.71 KB) 7g5m-plus.json
PDB		pdb7g5m.ent.gz Display(147.16 KB) pdb7g5m.ent
RDF		7g5m.rdf.gz Visualize(145.28 KB) 7g5m.rdf
Structure factors		r7g5msf.ent.gz Display(8.76 MB) r7g5msf.ent
Biological unit (mmCIF format)		7g5m-assembly1.cif.gz Display(179.12 KB) 7g5m-assembly1.cif (A) *author and software defined assembly, 1 molecule(s) (monomeric)
Biological unit (PDB format)		7g5m.pdb1.gz Display(140.32 KB) 7g5m.pdb1 (A) *author and software defined assembly, 1 molecule(s) (monomeric)
Validation reports	PDF	7g5m_validation.pdf.gz Display(1.05 MB) 7g5m_validation.pdf
	PDF-full	7g5m_full_validation.pdf.gz Display(1.06 MB) 7g5m_full_validation.pdf
	mmCIF	7g5m_validation.cif.gz Display(53.41 KB) 7g5m_validation.cif
	XML	7g5m_validation.xml.gz Display(38.79 KB) 7g5m_validation.xml
	PNG	7g5m_multipercentile_validation.png.gz Display(168.27 KB) 7g5m_multipercentile_validation.png
	SVG	7g5m_multipercentile_validation.svg.gz Display(974.00 B) 7g5m_multipercentile_validation.svg
EDMap	2fo-fc (PDBx/mmCIF)	7g5m_validation_2fo-fc_map_coef.cif.gz Display(910.75 KB) 7g5m_validation_2fo-fc_map_coef.cif
	fo-fc (PDBx/mmCIF)	7g5m_validation_fo-fc_map_coef.cif.gz Display(909.66 KB) 7g5m_validation_fo-fc_map_coef.cif
	2fo-fc (MTZ)	7g5m_validation_2fo-fc_map_coef.mtz Visualize(1.47 MB)
	fo-fc (MTZ)	7g5m_validation_fo-fc_map_coef.mtz Visualize(1.47 MB)

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)