Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7G2Y

Crystal Structure of rat Autotaxin in complex with 2-[(R)-2-[1-[3-[2-[(5-methyltetrazol-2-yl)methyl]-4-(trifluoromethyl)phenyl]propanoyl]piperidin-4-yl]ethylsulfinyl]-1,3-thiazole-5-sulfonamide, i.e. SMILES C1(=NC=C(S(=O)(=O)N)S1)[S@](=O)CC[C@H]1CCN(C(=O)CCc2ccc(C(F)(F)F)cc2CN2N=NC(=N2)C)CC1 with IC50=0.00230987 microM

Resources

File format		File name (file size)
PDBx/mmCIF		7g2y.cif.gz Display(202.17 KB) 7g2y.cif
PDBx/mmJSON	all	7g2y.json.gz Display (Tree)(137.32 KB) 7g2y.json
	no-atom	7g2y-noatom.json.gz Display (Header)(28.92 KB) 7g2y-noatom.json
	add only	7g2y-plus.json.gz Display(1.94 KB) 7g2y-plus.json
PDBML	all	7g2y.xml.gz Display(270.83 KB) 7g2y.xml
	no-atom	7g2y-noatom.xml.gz Display(54.33 KB) 7g2y-noatom.xml
	ext-atom	7g2y-extatom.xml.gz Display(163.62 KB) 7g2y-extatom.xml
pdb_nextgen	all	pdb_00007g2y_xyz-enrich.cif.gz Display(221.66 KB) pdb_00007g2y_xyz-enrich.cif
	no-atom	pdb_00007g2y_xyz-no-atom-enrich.xml.gz Display(64.39 KB) pdb_00007g2y_xyz-no-atom-enrich.xml
	ng-only	7g2y-plus.json.gz Display(4.71 KB) 7g2y-plus.json
PDB		pdb7g2y.ent.gz Display(153.93 KB) pdb7g2y.ent
RDF		7g2y.rdf.gz Visualize(150.59 KB) 7g2y.rdf
Structure factors		r7g2ysf.ent.gz Display(14.90 MB) r7g2ysf.ent
Biological unit (mmCIF format)		7g2y-assembly1.cif.gz Display(187.15 KB) 7g2y-assembly1.cif (A) *author and software defined assembly, 1 molecule(s) (monomeric)
Biological unit (PDB format)		7g2y.pdb1.gz Display(146.58 KB) 7g2y.pdb1 (A) *author and software defined assembly, 1 molecule(s) (monomeric)
Validation reports	PDF	7g2y_validation.pdf.gz Display(1.10 MB) 7g2y_validation.pdf
	PDF-full	7g2y_full_validation.pdf.gz Display(1.10 MB) 7g2y_full_validation.pdf
	mmCIF	7g2y_validation.cif.gz Display(58.51 KB) 7g2y_validation.cif
	XML	7g2y_validation.xml.gz Display(40.71 KB) 7g2y_validation.xml
	PNG	7g2y_multipercentile_validation.png.gz Display(163.87 KB) 7g2y_multipercentile_validation.png
	SVG	7g2y_multipercentile_validation.svg.gz Display(959.00 B) 7g2y_multipercentile_validation.svg
EDMap	2fo-fc (PDBx/mmCIF)	7g2y_validation_2fo-fc_map_coef.cif.gz Display(1.46 MB) 7g2y_validation_2fo-fc_map_coef.cif
	fo-fc (PDBx/mmCIF)	7g2y_validation_fo-fc_map_coef.cif.gz Display(1.46 MB) 7g2y_validation_fo-fc_map_coef.cif
	2fo-fc (MTZ)	7g2y_validation_2fo-fc_map_coef.mtz Visualize(2.42 MB)
	fo-fc (MTZ)	7g2y_validation_fo-fc_map_coef.mtz Visualize(2.42 MB)

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)