Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7G2M

Crystal Structure of rat Autotaxin in complex with 5-fluoro-6-[2-[3-[2-[(5-methyltetrazol-2-yl)methyl]-4-(trifluoromethyl)phenyl]propanoyl]-1,3,4,6-tetrahydropyrrolo[3,4-c]pyrrole-5-carbonyl]pyridine-3-sulfonamide, i.e. SMILES C12=C(CN(C1)C(=O)CCc1ccc(cc1CN1N=NC(=N1)C)C(F)(F)F)CN(C2)C(=O)c1ncc(cc1F)S(=O)(=O)N with IC50=0.0018642 microM

Resources

File format		File name (file size)
PDBx/mmCIF		7g2m.cif.gz Display(188.29 KB) 7g2m.cif
PDBx/mmJSON	all	7g2m.json.gz Display (Tree)(124.84 KB) 7g2m.json
	no-atom	7g2m-noatom.json.gz Display (Header)(25.24 KB) 7g2m-noatom.json
	add only	7g2m-plus.json.gz Display(1.94 KB) 7g2m-plus.json
PDBML	all	7g2m.xml.gz Display(251.89 KB) 7g2m.xml
	no-atom	7g2m-noatom.xml.gz Display(49.61 KB) 7g2m-noatom.xml
	ext-atom	7g2m-extatom.xml.gz Display(151.83 KB) 7g2m-extatom.xml
pdb_nextgen	all	pdb_00007g2m_xyz-enrich.cif.gz Display(206.57 KB) pdb_00007g2m_xyz-enrich.cif
	no-atom	pdb_00007g2m_xyz-no-atom-enrich.xml.gz Display(59.08 KB) pdb_00007g2m_xyz-no-atom-enrich.xml
	ng-only	7g2m-plus.json.gz Display(4.71 KB) 7g2m-plus.json
PDB		pdb7g2m.ent.gz Display(143.02 KB) pdb7g2m.ent
RDF		7g2m.rdf.gz Visualize(142.72 KB) 7g2m.rdf
Structure factors		r7g2msf.ent.gz Display(4.35 MB) r7g2msf.ent
Biological unit (mmCIF format)		7g2m-assembly1.cif.gz Display(174.27 KB) 7g2m-assembly1.cif (A) *author and software defined assembly, 1 molecule(s) (monomeric)
Biological unit (PDB format)		7g2m.pdb1.gz Display(136.36 KB) 7g2m.pdb1 (A) *author and software defined assembly, 1 molecule(s) (monomeric)
Validation reports	PDF	7g2m_validation.pdf.gz Display(1.08 MB) 7g2m_validation.pdf
	PDF-full	7g2m_full_validation.pdf.gz Display(1.08 MB) 7g2m_full_validation.pdf
	mmCIF	7g2m_validation.cif.gz Display(49.12 KB) 7g2m_validation.cif
	XML	7g2m_validation.xml.gz Display(35.91 KB) 7g2m_validation.xml
	PNG	7g2m_multipercentile_validation.png.gz Display(165.07 KB) 7g2m_multipercentile_validation.png
	SVG	7g2m_multipercentile_validation.svg.gz Display(949.00 B) 7g2m_multipercentile_validation.svg
EDMap	2fo-fc (PDBx/mmCIF)	7g2m_validation_2fo-fc_map_coef.cif.gz Display(516.67 KB) 7g2m_validation_2fo-fc_map_coef.cif
	fo-fc (PDBx/mmCIF)	7g2m_validation_fo-fc_map_coef.cif.gz Display(515.79 KB) 7g2m_validation_fo-fc_map_coef.cif
	2fo-fc (MTZ)	7g2m_validation_2fo-fc_map_coef.mtz Visualize(846.01 KB)
	fo-fc (MTZ)	7g2m_validation_fo-fc_map_coef.mtz Visualize(846.01 KB)

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)