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6EEA

Bioreductive 4-hydroxy-3-nitro-5-ureido-benzenesulfonamides selectively target the tumor-associated carbonic anhydrase isoforms IX and XII and show hypoxia-enhanced cytotoxicity against human cancer cell lines.

Resources
File formatFile name (file size)
PDBx/mmCIF6eea.cif.gz Display(119.99 KB)
6eea.cif
PDBx/mmJSONall6eea.json.gz Display (Tree)(85.41 KB)
6eea.json
no-atom6eea-noatom.json.gz Display (Header)(15.33 KB)
6eea-noatom.json
add only6eea-plus.json.gz Display(1.91 KB)
6eea-plus.json
PDBMLall6eea.xml.gz Display(161.65 KB)
6eea.xml
no-atom6eea-noatom.xml.gz Display(25.75 KB)
6eea-noatom.xml
ext-atom6eea-extatom.xml.gz Display(48.19 KB)
6eea-extatom.xml
pdb_nextgenallpdb_00006eea_xyz-enrich.cif.gz Display(126.73 KB)
pdb_00006eea_xyz-enrich.cif
no-atompdb_00006eea_xyz-no-atom-enrich.xml.gz Display(32.88 KB)
pdb_00006eea_xyz-no-atom-enrich.xml
ng-only6eea-plus.json.gz Display(1.99 KB)
6eea-plus.json
PDBpdb6eea.ent.gz Display(90.06 KB)
pdb6eea.ent
RDF6eea.rdf.gz Visualize(72.59 KB)
6eea.rdf
Structure factorsr6eeasf.ent.gz Display(762.75 KB)
r6eeasf.ent
Biological unit (mmCIF format)6eea-assembly1.cif.gz Display(108.16 KB)
6eea-assembly1.cif (A)

*author and software defined assembly, 1 molecule(s) (monomeric)

Biological unit (PDB format)6eea.pdb1.gz Display(85.20 KB)
6eea.pdb1 (A)

*author and software defined assembly, 1 molecule(s) (monomeric)

Validation reportsPDF6eea_validation.pdf.gz Display(946.40 KB)
6eea_validation.pdf
PDF-full6eea_full_validation.pdf.gz Display(952.12 KB)
6eea_full_validation.pdf
mmCIF6eea_validation.cif.gz Display(16.50 KB)
6eea_validation.cif
XML6eea_validation.xml.gz Display(12.82 KB)
6eea_validation.xml
PNG6eea_multipercentile_validation.png.gz Display(167.11 KB)
6eea_multipercentile_validation.png
SVG6eea_multipercentile_validation.svg.gz Display(957.00 B)
6eea_multipercentile_validation.svg
EDMap2fo-fc (PDBx/mmCIF)6eea_validation_2fo-fc_map_coef.cif.gz Display(303.27 KB)
6eea_validation_2fo-fc_map_coef.cif
fo-fc (PDBx/mmCIF)6eea_validation_fo-fc_map_coef.cif.gz Display(283.18 KB)
6eea_validation_fo-fc_map_coef.cif
2fo-fc (MTZ)6eea_validation_2fo-fc_map_coef.mtz Visualize(737.36 KB)
fo-fc (MTZ)6eea_validation_fo-fc_map_coef.mtz Visualize(737.36 KB)

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PDB entries from 2025-06-18

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