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5VP1

Discovery of Clinical Candidate N-{(1S)-1-[3-Fluoro-4-(trifluoromethoxy)phenyl]-2-methoxyethyl}-7-methoxy-2-oxo-2,3-dihydropyrido[2,3-b]pyrazine-4(1H)-carboxamide (TAK-915), A Highly Potent, Selective, and Brain-Penetrating Phosphodiesterase 2A Inhibitor for the Treatment of Cognitive Disorders

Resources
File formatFile name (file size)
PDBx/mmCIF5vp1.cif.gz Display(423.79 KB)
5vp1.cif
PDBx/mmJSONall5vp1.json.gz Display (Tree)(276.09 KB)
5vp1.json
no-atom5vp1-noatom.json.gz Display (Header)(20.29 KB)
5vp1-noatom.json
add only5vp1-plus.json.gz Display(1.38 KB)
5vp1-plus.json
PDBMLall5vp1.xml.gz Display(584.21 KB)
5vp1.xml
no-atom5vp1-noatom.xml.gz Display(48.20 KB)
5vp1-noatom.xml
ext-atom5vp1-extatom.xml.gz Display(192.20 KB)
5vp1-extatom.xml
pdb_nextgenallpdb_00005vp1_xyz-enrich.cif.gz Display(433.43 KB)
pdb_00005vp1_xyz-enrich.cif
no-atompdb_00005vp1_xyz-no-atom-enrich.xml.gz Display(55.60 KB)
pdb_00005vp1_xyz-no-atom-enrich.xml
ng-only5vp1-plus.json.gz Display(2.08 KB)
5vp1-plus.json
PDBpdb5vp1.ent.gz Display(349.11 KB)
pdb5vp1.ent
RDF5vp1.rdf.gz Visualize(130.69 KB)
5vp1.rdf
Structure factorsr5vp1sf.ent.gz Display(2.40 MB)
r5vp1sf.ent
Biological unit (mmCIF format)5vp1-assembly1.cif.gz Display(278.30 KB)
5vp1-assembly1.cif (A,C)

*author and software defined assembly, 2 molecule(s) (dimeric)

5vp1-assembly2.cif.gz Display(285.93 KB)
5vp1-assembly2.cif (B)

*author and software defined assembly, 2 molecule(s) (dimeric)

Biological unit (PDB format)5vp1.pdb1.gz Display(226.95 KB)
5vp1.pdb1 (A,C)

*author and software defined assembly, 2 molecule(s) (dimeric)

5vp1.pdb2.gz Display(233.95 KB)
5vp1.pdb2 (B)

*author and software defined assembly, 2 molecule(s) (dimeric)

Validation reportsPDF5vp1_validation.pdf.gz Display(1.43 MB)
5vp1_validation.pdf
PDF-full5vp1_full_validation.pdf.gz Display(1.44 MB)
5vp1_full_validation.pdf
mmCIF5vp1_validation.cif.gz Display(53.18 KB)
5vp1_validation.cif
XML5vp1_validation.xml.gz Display(38.01 KB)
5vp1_validation.xml
PNG5vp1_multipercentile_validation.png.gz Display(166.41 KB)
5vp1_multipercentile_validation.png
SVG5vp1_multipercentile_validation.svg.gz Display(943.00 B)
5vp1_multipercentile_validation.svg
EDMap2fo-fc (PDBx/mmCIF)5vp1_validation_2fo-fc_map_coef.cif.gz Display(878.80 KB)
5vp1_validation_2fo-fc_map_coef.cif
fo-fc (PDBx/mmCIF)5vp1_validation_fo-fc_map_coef.cif.gz Display(858.37 KB)
5vp1_validation_fo-fc_map_coef.cif
2fo-fc (MTZ)5vp1_validation_2fo-fc_map_coef.mtz Visualize(1.97 MB)
fo-fc (MTZ)5vp1_validation_fo-fc_map_coef.mtz Visualize(1.97 MB)

229183

PDB entries from 2024-12-18

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