Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5VP1

Discovery of Clinical Candidate N-{(1S)-1-[3-Fluoro-4-(trifluoromethoxy)phenyl]-2-methoxyethyl}-7-methoxy-2-oxo-2,3-dihydropyrido[2,3-b]pyrazine-4(1H)-carboxamide (TAK-915), A Highly Potent, Selective, and Brain-Penetrating Phosphodiesterase 2A Inhibitor for the Treatment of Cognitive Disorders

Resources

File format		File name (file size)
PDBx/mmCIF		5vp1.cif.gz Display(423.79 KB) 5vp1.cif
PDBx/mmJSON	all	5vp1.json.gz Display (Tree)(276.09 KB) 5vp1.json
	no-atom	5vp1-noatom.json.gz Display (Header)(20.29 KB) 5vp1-noatom.json
	add only	5vp1-plus.json.gz Display(1.38 KB) 5vp1-plus.json
PDBML	all	5vp1.xml.gz Display(584.21 KB) 5vp1.xml
	no-atom	5vp1-noatom.xml.gz Display(48.20 KB) 5vp1-noatom.xml
	ext-atom	5vp1-extatom.xml.gz Display(192.20 KB) 5vp1-extatom.xml
PDB		pdb5vp1.ent.gz Display(349.11 KB) pdb5vp1.ent
RDF		5vp1.rdf.gz Visualize(130.69 KB) 5vp1.rdf
Structure factors		r5vp1sf.ent.gz Display(2.40 MB) r5vp1sf.ent
Biological unit (mmCIF format)		5vp1-assembly1.cif.gz Display(278.30 KB) 5vp1-assembly1.cif (A,C) *author and software defined assembly, 2 molecule(s) (dimeric)
Biological unit (mmCIF format)		5vp1-assembly2.cif.gz Display(285.93 KB) 5vp1-assembly2.cif (B) *author and software defined assembly, 2 molecule(s) (dimeric)
Biological unit (PDB format)		5vp1.pdb1.gz Display(226.95 KB) 5vp1.pdb1 (A,C) *author and software defined assembly, 2 molecule(s) (dimeric)
Biological unit (PDB format)		5vp1.pdb2.gz Display(233.95 KB) 5vp1.pdb2 (B) *author and software defined assembly, 2 molecule(s) (dimeric)
Validation reports	PDF	5vp1_validation.pdf.gz Display(1.43 MB) 5vp1_validation.pdf
	PDF-full	5vp1_full_validation.pdf.gz Display(1.44 MB) 5vp1_full_validation.pdf
	mmCIF	5vp1_validation.cif.gz Display(53.18 KB) 5vp1_validation.cif
	XML	5vp1_validation.xml.gz Display(38.01 KB) 5vp1_validation.xml
	PNG	5vp1_multipercentile_validation.png.gz Display(166.41 KB) 5vp1_multipercentile_validation.png
	SVG	5vp1_multipercentile_validation.svg.gz Display(943.00 B) 5vp1_multipercentile_validation.svg
EDMap	2fo-fc (PDBx/mmCIF)	5vp1_validation_2fo-fc_map_coef.cif.gz Display(878.80 KB) 5vp1_validation_2fo-fc_map_coef.cif
	fo-fc (PDBx/mmCIF)	5vp1_validation_fo-fc_map_coef.cif.gz Display(858.37 KB) 5vp1_validation_fo-fc_map_coef.cif
	2fo-fc (MTZ)	5vp1_validation_2fo-fc_map_coef.mtz Visualize(1.97 MB)
	fo-fc (MTZ)	5vp1_validation_fo-fc_map_coef.mtz Visualize(1.97 MB)

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)