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5VP0

Discovery of Clinical Candidate N-{(1S)-1-[3-Fluoro-4-(trifluoromethoxy)phenyl]-2-methoxyethyl}-7-methoxy-2-oxo-2,3-dihydropyrido[2,3-b]pyrazine-4(1H)-carboxamide (TAK-915), A Highly Potent, Selective, and Brain-Penetrating Phosphodiesterase 2A Inhibitor for the Treatment of Cognitive Disorders

Resources
File formatFile name (file size)
PDBx/mmCIF5vp0.cif.gz Display(421.41 KB)
5vp0.cif
PDBx/mmJSONall5vp0.json.gz Display (Tree)(276.23 KB)
5vp0.json
no-atom5vp0-noatom.json.gz Display (Header)(19.50 KB)
5vp0-noatom.json
add only5vp0-plus.json.gz Display(1.37 KB)
5vp0-plus.json
PDBMLall5vp0.xml.gz Display(579.29 KB)
5vp0.xml
no-atom5vp0-noatom.xml.gz Display(44.95 KB)
5vp0-noatom.xml
ext-atom5vp0-extatom.xml.gz Display(187.78 KB)
5vp0-extatom.xml
pdb_nextgenallpdb_00005vp0_xyz-enrich.cif.gz Display(430.48 KB)
pdb_00005vp0_xyz-enrich.cif
no-atompdb_00005vp0_xyz-no-atom-enrich.xml.gz Display(52.27 KB)
pdb_00005vp0_xyz-no-atom-enrich.xml
ng-only5vp0-plus.json.gz Display(2.08 KB)
5vp0-plus.json
PDBpdb5vp0.ent.gz Display(345.20 KB)
pdb5vp0.ent
RDF5vp0.rdf.gz Visualize(125.35 KB)
5vp0.rdf
Structure factorsr5vp0sf.ent.gz Display(1.47 MB)
r5vp0sf.ent
Biological unit (mmCIF format)5vp0-assembly1.cif.gz Display(275.73 KB)
5vp0-assembly1.cif (A,C)

*author and software defined assembly, 2 molecule(s) (dimeric)

5vp0-assembly2.cif.gz Display(286.88 KB)
5vp0-assembly2.cif (B)

*author and software defined assembly, 2 molecule(s) (dimeric)

Biological unit (PDB format)5vp0.pdb1.gz Display(224.53 KB)
5vp0.pdb1 (A,C)

*author and software defined assembly, 2 molecule(s) (dimeric)

5vp0.pdb2.gz Display(233.80 KB)
5vp0.pdb2 (B)

*author and software defined assembly, 2 molecule(s) (dimeric)

Validation reportsPDF5vp0_validation.pdf.gz Display(1.31 MB)
5vp0_validation.pdf
PDF-full5vp0_full_validation.pdf.gz Display(1.31 MB)
5vp0_full_validation.pdf
mmCIF5vp0_validation.cif.gz Display(49.52 KB)
5vp0_validation.cif
XML5vp0_validation.xml.gz Display(36.00 KB)
5vp0_validation.xml
PNG5vp0_multipercentile_validation.png.gz Display(161.92 KB)
5vp0_multipercentile_validation.png
SVG5vp0_multipercentile_validation.svg.gz Display(949.00 B)
5vp0_multipercentile_validation.svg
EDMap2fo-fc (PDBx/mmCIF)5vp0_validation_2fo-fc_map_coef.cif.gz Display(539.05 KB)
5vp0_validation_2fo-fc_map_coef.cif
fo-fc (PDBx/mmCIF)5vp0_validation_fo-fc_map_coef.cif.gz Display(501.21 KB)
5vp0_validation_fo-fc_map_coef.cif
2fo-fc (MTZ)5vp0_validation_2fo-fc_map_coef.mtz Visualize(1.22 MB)
fo-fc (MTZ)5vp0_validation_fo-fc_map_coef.mtz Visualize(1.22 MB)

229183

PDB entries from 2024-12-18

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