Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5VP0

Discovery of Clinical Candidate N-{(1S)-1-[3-Fluoro-4-(trifluoromethoxy)phenyl]-2-methoxyethyl}-7-methoxy-2-oxo-2,3-dihydropyrido[2,3-b]pyrazine-4(1H)-carboxamide (TAK-915), A Highly Potent, Selective, and Brain-Penetrating Phosphodiesterase 2A Inhibitor for the Treatment of Cognitive Disorders

Resources

File format		File name (file size)
PDBx/mmCIF		5vp0.cif.gz Display(421.41 KB) 5vp0.cif
PDBx/mmJSON	all	5vp0.json.gz Display (Tree)(276.23 KB) 5vp0.json
	no-atom	5vp0-noatom.json.gz Display (Header)(19.50 KB) 5vp0-noatom.json
	add only	5vp0-plus.json.gz Display(1.46 KB) 5vp0-plus.json
PDBML	all	5vp0.xml.gz Display(579.29 KB) 5vp0.xml
	no-atom	5vp0-noatom.xml.gz Display(44.95 KB) 5vp0-noatom.xml
	ext-atom	5vp0-extatom.xml.gz Display(187.78 KB) 5vp0-extatom.xml
pdb_nextgen	all	pdb_00005vp0_xyz-enrich.cif.gz Display(446.06 KB) pdb_00005vp0_xyz-enrich.cif
	no-atom	pdb_00005vp0_xyz-no-atom-enrich.xml.gz Display(66.36 KB) pdb_00005vp0_xyz-no-atom-enrich.xml
	ng-only	5vp0-plus.json.gz Display(3.79 KB) 5vp0-plus.json
PDB		pdb5vp0.ent.gz Display(345.20 KB) pdb5vp0.ent
RDF		5vp0.rdf.gz Visualize(125.35 KB) 5vp0.rdf
Structure factors		r5vp0sf.ent.gz Display(1.47 MB) r5vp0sf.ent
Biological unit (mmCIF format)		5vp0-assembly1.cif.gz Display(275.73 KB) 5vp0-assembly1.cif (A,C) *author and software defined assembly, 2 molecule(s) (dimeric)
Biological unit (mmCIF format)		5vp0-assembly2.cif.gz Display(286.88 KB) 5vp0-assembly2.cif (B) *author and software defined assembly, 2 molecule(s) (dimeric)
Biological unit (PDB format)		5vp0.pdb1.gz Display(224.53 KB) 5vp0.pdb1 (A,C) *author and software defined assembly, 2 molecule(s) (dimeric)
Biological unit (PDB format)		5vp0.pdb2.gz Display(233.80 KB) 5vp0.pdb2 (B) *author and software defined assembly, 2 molecule(s) (dimeric)
Validation reports	PDF	5vp0_validation.pdf.gz Display(1.31 MB) 5vp0_validation.pdf
	PDF-full	5vp0_full_validation.pdf.gz Display(1.31 MB) 5vp0_full_validation.pdf
	mmCIF	5vp0_validation.cif.gz Display(49.52 KB) 5vp0_validation.cif
	XML	5vp0_validation.xml.gz Display(36.00 KB) 5vp0_validation.xml
	PNG	5vp0_multipercentile_validation.png.gz Display(161.92 KB) 5vp0_multipercentile_validation.png
	SVG	5vp0_multipercentile_validation.svg.gz Display(949.00 B) 5vp0_multipercentile_validation.svg
EDMap	2fo-fc (PDBx/mmCIF)	5vp0_validation_2fo-fc_map_coef.cif.gz Display(539.05 KB) 5vp0_validation_2fo-fc_map_coef.cif
	fo-fc (PDBx/mmCIF)	5vp0_validation_fo-fc_map_coef.cif.gz Display(501.21 KB) 5vp0_validation_fo-fc_map_coef.cif
	2fo-fc (MTZ)	5vp0_validation_2fo-fc_map_coef.mtz Visualize(1.22 MB)
	fo-fc (MTZ)	5vp0_validation_fo-fc_map_coef.mtz Visualize(1.22 MB)

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)