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4UWL

Discovery of (2S)-8-((3R)-3-Methylmorpholin-4-yl)-1-(3-methyl-2-oxo- butyl)-2-(trifluoromethyl)-3,4-dihydro-2H-pyrimido(1,2-a)pyrimidin-6- one: a Novel Potent and Selective Inhibitor of Vps34 for the Treatment of Solid Tumors

Resources
File formatFile name (file size)
PDBx/mmCIF4uwl.cif.gz Display(123.95 KB)
4uwl.cif
PDBx/mmJSONall4uwl.json.gz Display (Tree)(84.89 KB)
4uwl.json
no-atom4uwl-noatom.json.gz Display (Header)(15.82 KB)
4uwl-noatom.json
add only4uwl-plus.json.gz Display(963.00 B)
4uwl-plus.json
PDBMLall4uwl.xml.gz Display(167.38 KB)
4uwl.xml
no-atom4uwl-noatom.xml.gz Display(32.26 KB)
4uwl-noatom.xml
ext-atom4uwl-extatom.xml.gz Display(101.48 KB)
4uwl-extatom.xml
pdb_nextgenallpdb_00004uwl_xyz-enrich.cif.gz Display(138.16 KB)
pdb_00004uwl_xyz-enrich.cif
no-atompdb_00004uwl_xyz-no-atom-enrich.xml.gz Display(45.87 KB)
pdb_00004uwl_xyz-no-atom-enrich.xml
ng-only4uwl-plus.json.gz Display(4.49 KB)
4uwl-plus.json
PDBpdb4uwl.ent.gz Display(95.31 KB)
pdb4uwl.ent
RDF4uwl.rdf.gz Visualize(100.29 KB)
4uwl.rdf
Structure factorsr4uwlsf.ent.gz Display(185.68 KB)
r4uwlsf.ent
Biological unit (mmCIF format)4uwl-assembly1.cif.gz Display(115.13 KB)
4uwl-assembly1.cif (A)

*author and software defined assembly, 1 molecule(s) (monomeric)

Biological unit (PDB format)4uwl.pdb1.gz Display(90.55 KB)
4uwl.pdb1 (A)

*author and software defined assembly, 1 molecule(s) (monomeric)

Validation reportsPDF4uwl_validation.pdf.gz Display(840.76 KB)
4uwl_validation.pdf
PDF-full4uwl_full_validation.pdf.gz Display(843.72 KB)
4uwl_full_validation.pdf
mmCIF4uwl_validation.cif.gz Display(28.64 KB)
4uwl_validation.cif
XML4uwl_validation.xml.gz Display(20.56 KB)
4uwl_validation.xml
PNG4uwl_multipercentile_validation.png.gz Display(170.88 KB)
4uwl_multipercentile_validation.png
SVG4uwl_multipercentile_validation.svg.gz Display(976.00 B)
4uwl_multipercentile_validation.svg
EDMap2fo-fc (PDBx/mmCIF)4uwl_validation_2fo-fc_map_coef.cif.gz Display(206.70 KB)
4uwl_validation_2fo-fc_map_coef.cif
fo-fc (PDBx/mmCIF)4uwl_validation_fo-fc_map_coef.cif.gz Display(182.67 KB)
4uwl_validation_fo-fc_map_coef.cif
2fo-fc (MTZ)4uwl_validation_2fo-fc_map_coef.mtz Visualize(504.95 KB)
fo-fc (MTZ)4uwl_validation_fo-fc_map_coef.mtz Visualize(504.95 KB)

227111

PDB entries from 2024-11-06

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