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4K8S

Hydroxyethylamine-based inhibitors of BACE1: P1-P3 macrocyclization can improve potency, selectivity, and cell activity

Resources
File formatFile name (file size)
PDBx/mmCIF4k8s.cif.gz Display(227.37 KB)
4k8s.cif
PDBx/mmJSONall4k8s.json.gz Display (Tree)(141.65 KB)
4k8s.json
no-atom4k8s-noatom.json.gz Display (Header)(16.78 KB)
4k8s-noatom.json
add only4k8s-plus.json.gz Display(1.34 KB)
4k8s-plus.json
PDBMLall4k8s.xml.gz Display(313.21 KB)
4k8s.xml
no-atom4k8s-noatom.xml.gz Display(45.72 KB)
4k8s-noatom.xml
ext-atom4k8s-extatom.xml.gz Display(200.11 KB)
4k8s-extatom.xml
pdb_nextgenallpdb_00004k8s_xyz-enrich.cif.gz Display(258.51 KB)
pdb_00004k8s_xyz-enrich.cif
no-atompdb_00004k8s_xyz-no-atom-enrich.xml.gz Display(84.08 KB)
pdb_00004k8s_xyz-no-atom-enrich.xml
ng-only4k8s-plus.json.gz Display(7.75 KB)
4k8s-plus.json
PDBpdb4k8s.ent.gz Display(184.25 KB)
pdb4k8s.ent
RDF4k8s.rdf.gz Visualize(134.16 KB)
4k8s.rdf
Structure factorsr4k8ssf.ent.gz Display(912.88 KB)
r4k8ssf.ent
Biological unit (mmCIF format)4k8s-assembly1.cif.gz Display(77.28 KB)
4k8s-assembly1.cif (A)

*author and software defined assembly, 1 molecule(s) (monomeric)

4k8s-assembly2.cif.gz Display(76.42 KB)
4k8s-assembly2.cif (B)

*author and software defined assembly, 1 molecule(s) (monomeric)

4k8s-assembly3.cif.gz Display(77.87 KB)
4k8s-assembly3.cif (C)

*author and software defined assembly, 1 molecule(s) (monomeric)

Biological unit (PDB format)4k8s.pdb1.gz Display(62.80 KB)
4k8s.pdb1 (A)

*author and software defined assembly, 1 molecule(s) (monomeric)

4k8s.pdb2.gz Display(62.27 KB)
4k8s.pdb2 (B)

*author and software defined assembly, 1 molecule(s) (monomeric)

4k8s.pdb3.gz Display(63.02 KB)
4k8s.pdb3 (C)

*author and software defined assembly, 1 molecule(s) (monomeric)

Validation reportsPDF4k8s_validation.pdf.gz Display(1.34 MB)
4k8s_validation.pdf
PDF-full4k8s_full_validation.pdf.gz Display(1.36 MB)
4k8s_full_validation.pdf
mmCIF4k8s_validation.cif.gz Display(54.08 KB)
4k8s_validation.cif
XML4k8s_validation.xml.gz Display(39.66 KB)
4k8s_validation.xml
PNG4k8s_multipercentile_validation.png.gz Display(167.88 KB)
4k8s_multipercentile_validation.png
SVG4k8s_multipercentile_validation.svg.gz Display(981.00 B)
4k8s_multipercentile_validation.svg
EDMap2fo-fc (PDBx/mmCIF)4k8s_validation_2fo-fc_map_coef.cif.gz Display(943.79 KB)
4k8s_validation_2fo-fc_map_coef.cif
fo-fc (PDBx/mmCIF)4k8s_validation_fo-fc_map_coef.cif.gz Display(940.65 KB)
4k8s_validation_fo-fc_map_coef.cif
2fo-fc (MTZ)4k8s_validation_2fo-fc_map_coef.mtz Visualize(1.46 MB)
fo-fc (MTZ)4k8s_validation_fo-fc_map_coef.mtz Visualize(1.46 MB)

226707

PDB entries from 2024-10-30

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