Summary
| Title: | Human GAR transformylase in complex with GAR substrate and AGF302 inhibitor |
| Citation: | Tong, N.,Wong-Roushar, J.,Wallace-Povirk, A.,Shah, Y.,Nyman, M.C.,Katinas, J.M.,Schneider, M.,O'Connor, C.,Bao, X.,Kim, S.,Li, J.,Hou, Z.,Matherly, L.H.,Dann 3rd, C.E.,Gangjee, A. Multitargeted 6-Substituted Thieno[2,3- d ]pyrimidines as Folate Receptor-Selective Anticancer Agents that Inhibit Cytosolic and Mitochondrial One-Carbon Metabolism. Acs Pharmacol Transl Sci, 6:748-770, 2023 PubMed: 37200803DOI: 10.1021/acsptsci.3c00020 |
| Experimental method: | X-RAY DIFFRACTION (2.48 Å) |
| Deposition date: | 2022-12-05 |
| Release date: | 2023-05-10 |
| Obsoletion date: | 2025-04-02 |
Timeline
Downloads
| File format | File name (file size) | ||
| PDBx/mmCIF | 8fdz.cif.gz Display(57.68 KB) 8fdz.cif | ||
| PDBx/mmJSON | no-atom | 8fdz-noatom.json.gz Display (Header)(14.51 KB) 8fdz-noatom.json | |
| PDBML | all | 8fdz.xml.gz Display(73.47 KB) 8fdz.xml | |
| PDB | pdb8fdz.ent.gz Display(38.96 KB) pdb8fdz.ent | ||
| Structure factors | r8fdzsf.ent.gz Display(453.56 KB) r8fdzsf.ent | ||
