Summary
| Title: | Crystal structure of human tryptophan hydroxylase 1 in complex with inhibitor LP778902 |
| Citation: | Specker, E.,Matthes, S.,Wesolowski, R.,Schutz, A.,Grohmann, M.,Alenina, N.,Pleimes, D.,Mallow, K.,Neuenschwander, M.,Gogolin, A.,Weise, M.,Pfeifer, J.,Ziebart, N.,Heinemann, U.,von Kries, J.P.,Nazare, M.,Bader, M. Structure-Based Design of Xanthine-Benzimidazole Derivatives as Novel and Potent Tryptophan Hydroxylase Inhibitors. J.Med.Chem., 65:11126-11149, 2022 PubMed: 35921615DOI: 10.1021/acs.jmedchem.2c00598 |
| Experimental method: | X-RAY DIFFRACTION (2.58925907124 Å) |
| Deposition date: | 2022-04-08 |
| Release date: | 2022-09-07 |
| Obsoletion date: | 2025-07-16 |
Timeline
Downloads
| File format | File name (file size) | ||
| PDBx/mmCIF | 7zik.cif.gz Display(282.58 KB) 7zik.cif | ||
| PDBx/mmJSON | no-atom | 7zik-noatom.json.gz Display (Header)(18.22 KB) 7zik-noatom.json | |
| PDBML | all | 7zik.xml.gz Display(369.11 KB) 7zik.xml | |
| PDB | pdb7zik.ent.gz Display(188.74 KB) pdb7zik.ent | ||
| Structure factors | r7ziksf.ent.gz Display(120.15 KB) r7ziksf.ent | ||
