Summary
Title: | CDK2/Cyclin A in complex with compound 73 |
Citation: | Coxon, C.R.,Anscombe, E.,Harnor, S.J.,Martin, M.P.,Carbain, B.,Golding, B.T.,Hardcastle, I.R.,Harlow, L.K.,Korolchuk, S.,Matheson, C.J.,Newell, D.R.,Noble, M.E.,Sivaprakasam, M.,Tudhope, S.J.,Turner, D.M.,Wang, L.Z.,Wedge, S.R.,Wong, C.,Griffin, R.J.,Endicott, J.A.,Cano, C. Cyclin-Dependent Kinase (CDK) Inhibitors: Structure-Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines. J. Med. Chem., 60:1746-1767, 2017 PubMed: 28005359DOI: 10.1021/acs.jmedchem.6b01254 |
Experimental method: | X-RAY DIFFRACTION (2.97 Å) |
Deposition date: | 2016-08-17 |
Release date: | 2017-01-11 |
Obsoletion date: | 2017-05-10 |
Timeline
Downloads
File format | File name (file size) | ||
PDBx/mmCIF | 5lqe.cif.gz Display(228.78 KB) 5lqe.cif | ||
PDBx/mmJSON | no-atom | 5lqe-noatom.json.gz Display (Header)(16.38 KB) 5lqe-noatom.json | |
PDBML | all | 5lqe.xml.gz Display(308.78 KB) 5lqe.xml | |
PDB | pdb5lqe.ent.gz Display(190.22 KB) pdb5lqe.ent | ||
Structure factors | r5lqesf.ent.gz Display(227.83 KB) r5lqesf.ent |