Summary
| Title: | Crystal structure of thrombin in complex with a novel glucose-conjugated potent inhibitor |
| Citation: | Belviso, B.D.,Caliandro, R.,de Candia, M.,Zaetta, G.,Lopopolo, G.,Incampo, F.,Colucci, M.,Altomare, C.D. How a beta-d-Glucoside Side Chain Enhances Binding Affinity to Thrombin of Inhibitors Bearing 2-Chlorothiophene as P1 Moiety: Crystallography, Fragment Deconstruction Study, and Evaluation of Antithrombotic Properties. J.Med.Chem., 57:8563-8575, 2014 PubMed: 25268757DOI: 10.1021/jm5010754 |
| Experimental method: | X-RAY DIFFRACTION (1.94 Å) |
| Deposition date: | 2013-10-07 |
| Release date: | 2013-10-30 |
| Obsoletion date: | 2017-12-13 |
Timeline
Downloads
| File format | File name (file size) | ||
| PDBx/mmCIF | 4n3l.cif.gz Display(71.16 KB) 4n3l.cif | ||
| PDBx/mmJSON | no-atom | 4n3l-noatom.json.gz Display (Header)(11.03 KB) 4n3l-noatom.json | |
| PDBML | all | 4n3l.xml.gz Display(95.28 KB) 4n3l.xml | |
| PDB | pdb4n3l.ent.gz Display(56.51 KB) pdb4n3l.ent | ||
| Structure factors | r4n3lsf.ent.gz Display(422.00 KB) r4n3lsf.ent | ||
