Summary
| Title: | Crystal structure of C-RAF (Raf-1) |
| Citation: | Hatzivassiliou, G.,Song, K.,Yen, I.,Brandhuber, B.J.,Anderson, D.J.,Alvarado, R.,Ludlam, M.J.,Stokoe, D.,Gloor, S.L.,Vigers, G.,Morales, T.,Aliagas, I.,Liu, B.,Sideris, S.,Hoeflich, K.P.,Jaiswal, B.S.,Seshagiri, S.,Koeppen, H.,Belvin, M.,Friedman, L.S.,Malek, S. RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth. Nature, 464:431-435, 2010 PubMed: 20130576DOI: 10.1038/nature08833 |
| Experimental method: | X-RAY DIFFRACTION (4 Å) |
| Deposition date: | 2010-01-07 |
| Release date: | 2010-02-02 |
| Obsoletion date: | 2010-09-15 |
Timeline
Downloads
| File format | File name (file size) | ||
| PDBx/mmCIF | 3lb7.cif.gz Display(98.99 KB) 3lb7.cif | ||
| PDBx/mmJSON | no-atom | 3lb7-noatom.json.gz Display (Header)(9.95 KB) 3lb7-noatom.json | |
| PDBML | all | 3lb7.xml.gz Display(134.95 KB) 3lb7.xml | |
| PDB | pdb3lb7.ent.gz Display(78.99 KB) pdb3lb7.ent | ||
| Structure factors | r3lb7sf.ent.gz Display(139.47 KB) r3lb7sf.ent | ||
