Summary
| Title: | Crystal structure of the oncogenic tyrosine phosphatase SHP2 complexed with a salicylic acid-based small molecule inhibitor |
| Citation: | Zhang, X.,He, Y.,Liu, S.,Yu, Z.,Jiang, Z.X.,Yang, Z.,Dong, Y.,Nabinger, S.C.,Wu, L.,Gunawan, A.M.,Wang, L.,Chan, R.J.,Zhang, Z.Y. Salicylic Acid Based Small Molecule Inhibitor for the Oncogenic Src Homology-2 Domain Containing Protein Tyrosine Phosphatase-2 (SHP2). J.Med.Chem., 53:2482-2493, 2010 PubMed: 20170098DOI: 10.1021/jm901645u |
| Experimental method: | X-RAY DIFFRACTION (2 Å) |
| Deposition date: | 2009-09-08 |
| Release date: | 2010-03-02 |
| Obsoletion date: | 2010-08-11 |
Timeline
Downloads
| File format | File name (file size) | ||
| PDBx/mmCIF | 3jrl.cif.gz Display(63.31 KB) 3jrl.cif | ||
| PDBx/mmJSON | no-atom | 3jrl-noatom.json.gz Display (Header)(8.91 KB) 3jrl-noatom.json | |
| PDBML | all | 3jrl.xml.gz Display(84.02 KB) 3jrl.xml | |
| PDB | pdb3jrl.ent.gz Display(49.85 KB) pdb3jrl.ent | ||
| Structure factors | r3jrlsf.ent.gz Display(244.32 KB) r3jrlsf.ent | ||
