Summary
| Title: | B-Raf Kinase V600E Oncogenic Mutant in Complex with PLX3203 |
| Citation: | Tsai, J.,Lee, J.T.,Wang, W.,Zhang, J.,Cho, H.,Mamo, S.,Bremer, R.,Gillette, S.,Kong, J.,Haass, N.K.,Sproesser, K.,Li, L.,Smalley, K.S.,Fong, D.,Zhu, Y.L.,Marimuthu, A.,Nguyen, H.,Lam, B.,Liu, J.,Cheung, I.,Rice, J.,Suzuki, Y.,Luu, C.,Settachatgul, C.,Shellooe, R.,Cantwell, J.,Kim, S.H.,Schlessinger, J.,Zhang, K.Y.,West, B.L.,Powell, B.,Habets, G.,Zhang, C.,Ibrahim, P.N.,Hirth, P.,Artis, D.R.,Herlyn, M.,Bollag, G. Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity Proc.Natl.Acad.Sci.Usa, 105:3041-3046, 2008 PubMed: 18287029DOI: 10.1073/pnas.0711741105 |
| Experimental method: | X-RAY DIFFRACTION (2.65 Å) |
| Deposition date: | 2008-01-29 |
| Release date: | 2008-02-26 |
| Obsoletion date: | 2012-08-08 |
Timeline
Downloads
| File format | File name (file size) | ||
| PDBx/mmCIF | 3c4d.cif.gz Display(110.83 KB) 3c4d.cif | ||
| PDBML | all | 3c4d.xml.gz Display(149.31 KB) 3c4d.xml | |
| PDB | pdb3c4d.ent.gz Display(90.91 KB) pdb3c4d.ent | ||
