Summary
| Title: | Structure of 4-(4-tert-Butylbenzyl)-1-(7H-pyrrolo(2,3-d)pyrimidin-4- yl)piperidin-4-amine bound to PKB |
| Citation: | Mchardy, T.,Caldwell, J.J.,Cheung, K.M.,Hunter, L.J.,Taylor, K.,Rowlands, M.,Ruddle, R.,Henley, A.,De Haven Brandon, A.,Valenti, M.,Davies, T.G.,Fazal, L.,Seavers, L.,Raynaud, F.I.,Eccles, S.A.,Aherne, G.W.,Garrett, M.D.,Collins, I. Discovery of 4-Amino-1-(7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)Piperidine-4-Carboxamides as Selective, Orally Active Inhibitors of Protein Kinase B (Akt). J.Med.Chem., 2010 PubMed: 20151677DOI: 10.1021/JM901788J |
| Experimental method: | X-RAY DIFFRACTION (2.72 Å) |
| Deposition date: | 2010-01-22 |
| Release date: | 2010-02-23 |
| Obsoletion date: | 2010-06-16 |
Timeline
Downloads
| File format | File name (file size) | ||
| PDBx/mmCIF | 2x37.cif.gz Display(78.71 KB) 2x37.cif | ||
| PDBx/mmJSON | no-atom | 2x37-noatom.json.gz Display (Header)(11.50 KB) 2x37-noatom.json | |
| PDBML | all | 2x37.xml.gz Display(104.25 KB) 2x37.xml | |
| PDB | pdb2x37.ent.gz Display(63.40 KB) pdb2x37.ent | ||
| Structure factors | r2x37sf.ent.gz Display(186.45 KB) r2x37sf.ent | ||
