Summary
Title: | Structure of Aldehyde Reductase Holoenzyme in Complex with the Potent Aldose Reductase Inhibitor Fidarestat: Implications for Inhibitor Binding and Selectivity |
Citation: | El-Kabbani, O.,Carbone, V.,Darmanin, C.,Oka, M.,Mitschler, A.,Podjarny, A.,Schulze-Briese, C.,Chung, R.P. Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity. J.Med.Chem., 48:5536-5542, 2005 PubMed: 16107153DOI: 10.1021/jm050412o |
Experimental method: | X-RAY DIFFRACTION (1.85 Å) |
Deposition date: | 2005-08-11 |
Release date: | 2005-10-04 |
Obsoletion date: | 2009-05-05 |
Timeline
Downloads
ファイル形式 | ファイル名 (ファイルサイズ) | ||
PDBx/mmCIF | 2ao0.cif.gz 画面表示(84.80 KB) 2ao0.cif | ||
PDBx/mmJSON | ヘッダのみ | 2ao0-noatom.json.gz 画面表示 (Header)(11.46 KB) 2ao0-noatom.json | |
PDBML | 全ての情報 | 2ao0.xml.gz 画面表示(114.26 KB) 2ao0.xml | |
PDB | pdb2ao0.ent.gz 画面表示(69.03 KB) pdb2ao0.ent | ||
構造因子 | r2ao0sf.ent.gz 画面表示(257.86 KB) r2ao0sf.ent |