9ZY0

Cryo-EM structure of the monomeric HIV-2 Vif-human APOBEC3H-CBFbeta complex

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0000122	biological_process	negative regulation of transcription by RNA polymerase II
B	0000209	biological_process	protein polyubiquitination
B	0003677	molecular_function	DNA binding
B	0003713	molecular_function	transcription coactivator activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0006355	biological_process	regulation of DNA-templated transcription
B	0006357	biological_process	regulation of transcription by RNA polymerase II
B	0006366	biological_process	transcription by RNA polymerase II
B	0016020	cellular_component	membrane
B	0016513	cellular_component	core-binding factor complex
B	0043371	biological_process	negative regulation of CD4-positive, alpha-beta T cell differentiation
B	0043378	biological_process	positive regulation of CD8-positive, alpha-beta T cell differentiation
B	0043565	molecular_function	sequence-specific DNA binding
B	0045893	biological_process	positive regulation of DNA-templated transcription
C	0004126	molecular_function	cytidine deaminase activity
C	0005737	cellular_component	cytoplasm
C	0010526	biological_process	transposable element silencing
C	0044355	biological_process	clearance of foreign intracellular DNA
C	0045071	biological_process	negative regulation of viral genome replication
C	0051607	biological_process	defense response to virus

Functional Information from PROSITE/UniProt

site_id	PS00903
Number of Residues	39
Details	CYT_DCMP_DEAMINASES_1 Cytidine and deoxycytidylate deaminases zinc-binding region signature. HAEicFIneiksmgldetqcyqvtcyltws..........PCss......CaweL

Chain	Residue	Details
C	HIS54-LEU92

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