Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

9ZNI

Cryo-EM structure of the Methanosarcina acetivorans 70S ribosome in complex with SriC and SriD

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
Aa	0002181	biological_process	cytoplasmic translation
Aa	0003735	molecular_function	structural constituent of ribosome
Aa	0006412	biological_process	translation
Aa	0022625	cellular_component	cytosolic large ribosomal subunit
AA	0002181	biological_process	cytoplasmic translation
AA	0003723	molecular_function	RNA binding
AA	0003735	molecular_function	structural constituent of ribosome
AA	0006412	biological_process	translation
AA	0019843	molecular_function	rRNA binding
AA	0022625	cellular_component	cytosolic large ribosomal subunit
Ab	0006412	biological_process	translation
AB	0003723	molecular_function	RNA binding
AB	0003735	molecular_function	structural constituent of ribosome
AB	0006412	biological_process	translation
AB	0019843	molecular_function	rRNA binding
AB	0022625	cellular_component	cytosolic large ribosomal subunit
Ac	0006412	biological_process	translation
Ac	0008270	molecular_function	zinc ion binding
Ac	0070180	molecular_function	large ribosomal subunit rRNA binding
AC	0003723	molecular_function	RNA binding
AC	0003735	molecular_function	structural constituent of ribosome
AC	0006412	biological_process	translation
AC	0019843	molecular_function	rRNA binding
AC	0022625	cellular_component	cytosolic large ribosomal subunit
Ad	0006412	biological_process	translation
Ad	0008270	molecular_function	zinc ion binding
Ad	0070180	molecular_function	large ribosomal subunit rRNA binding
AD	0000049	molecular_function	tRNA binding
AD	0003723	molecular_function	RNA binding
AD	0003735	molecular_function	structural constituent of ribosome
AD	0006412	biological_process	translation
AD	0019843	molecular_function	rRNA binding
AD	0022625	cellular_component	cytosolic large ribosomal subunit
AE	0002181	biological_process	cytoplasmic translation
AE	0003735	molecular_function	structural constituent of ribosome
AE	0006412	biological_process	translation
AE	0019843	molecular_function	rRNA binding
AE	0022625	cellular_component	cytosolic large ribosomal subunit
AF	0001682	biological_process	tRNA 5'-leader removal
AF	0004526	molecular_function	ribonuclease P activity
AF	0005737	cellular_component	cytoplasm
AF	0006412	biological_process	translation
AG	0003729	molecular_function	mRNA binding
AG	0003735	molecular_function	structural constituent of ribosome
AG	0005840	cellular_component	ribosome
AG	0006412	biological_process	translation
AG	0017148	biological_process	negative regulation of translation
AG	0022625	cellular_component	cytosolic large ribosomal subunit
AH	0003735	molecular_function	structural constituent of ribosome
AH	0006412	biological_process	translation
AH	0019843	molecular_function	rRNA binding
AH	0022625	cellular_component	cytosolic large ribosomal subunit
AH	0070180	molecular_function	large ribosomal subunit rRNA binding
AI	0003735	molecular_function	structural constituent of ribosome
AI	0006412	biological_process	translation
AI	0019843	molecular_function	rRNA binding
AI	0022625	cellular_component	cytosolic large ribosomal subunit
AJ	0002181	biological_process	cytoplasmic translation
AJ	0003735	molecular_function	structural constituent of ribosome
AJ	0006412	biological_process	translation
AJ	0022625	cellular_component	cytosolic large ribosomal subunit
AK	0003735	molecular_function	structural constituent of ribosome
AK	0006412	biological_process	translation
AK	0022625	cellular_component	cytosolic large ribosomal subunit
AL	0000027	biological_process	ribosomal large subunit assembly
AL	0003735	molecular_function	structural constituent of ribosome
AL	0006412	biological_process	translation
AL	0008097	molecular_function	5S rRNA binding
AL	0019843	molecular_function	rRNA binding
AL	0022625	cellular_component	cytosolic large ribosomal subunit
AM	0002181	biological_process	cytoplasmic translation
AM	0003735	molecular_function	structural constituent of ribosome
AM	0006412	biological_process	translation
AM	0022625	cellular_component	cytosolic large ribosomal subunit
AN	0006412	biological_process	translation
AN	0070180	molecular_function	large ribosomal subunit rRNA binding
AO	0006412	biological_process	translation
AO	0070180	molecular_function	large ribosomal subunit rRNA binding
AP	0003735	molecular_function	structural constituent of ribosome
AP	0006412	biological_process	translation
AP	0022625	cellular_component	cytosolic large ribosomal subunit
AQ	0002181	biological_process	cytoplasmic translation
AQ	0003735	molecular_function	structural constituent of ribosome
AQ	0006412	biological_process	translation
AQ	0019843	molecular_function	rRNA binding
AQ	0022625	cellular_component	cytosolic large ribosomal subunit
AR	0006412	biological_process	translation
AR	0019843	molecular_function	rRNA binding
AS	0002181	biological_process	cytoplasmic translation
AS	0003735	molecular_function	structural constituent of ribosome
AS	0006412	biological_process	translation
AS	0019843	molecular_function	rRNA binding
AS	0022625	cellular_component	cytosolic large ribosomal subunit
AT	0006412	biological_process	translation
AT	0008270	molecular_function	zinc ion binding
AT	0019843	molecular_function	rRNA binding
AU	0006412	biological_process	translation
AV	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AV	0003723	molecular_function	RNA binding
AV	0003735	molecular_function	structural constituent of ribosome
AV	0006412	biological_process	translation
AV	0022625	cellular_component	cytosolic large ribosomal subunit
AW	0003723	molecular_function	RNA binding
AW	0003735	molecular_function	structural constituent of ribosome
AW	0006412	biological_process	translation
AW	0022625	cellular_component	cytosolic large ribosomal subunit
AX	0002181	biological_process	cytoplasmic translation
AX	0003735	molecular_function	structural constituent of ribosome
AX	0006412	biological_process	translation
AX	0022625	cellular_component	cytosolic large ribosomal subunit
AY	0006412	biological_process	translation
AY	0022625	cellular_component	cytosolic large ribosomal subunit
AZ	0006412	biological_process	translation
AZ	0008270	molecular_function	zinc ion binding
BA	0003735	molecular_function	structural constituent of ribosome
BA	0005829	cellular_component	cytosol
BA	0006412	biological_process	translation
BB	0000028	biological_process	ribosomal small subunit assembly
BB	0003735	molecular_function	structural constituent of ribosome
BB	0006412	biological_process	translation
BB	0022627	cellular_component	cytosolic small ribosomal subunit
BC	0003735	molecular_function	structural constituent of ribosome
BC	0006412	biological_process	translation
BC	0019843	molecular_function	rRNA binding
BC	0022627	cellular_component	cytosolic small ribosomal subunit
BD	0003735	molecular_function	structural constituent of ribosome
BD	0006412	biological_process	translation
BD	0015935	cellular_component	small ribosomal subunit
BD	0019843	molecular_function	rRNA binding
BD	0042274	biological_process	ribosomal small subunit biogenesis
BD	0043226	cellular_component	organelle
BE	0003723	molecular_function	RNA binding
BE	0003735	molecular_function	structural constituent of ribosome
BE	0006412	biological_process	translation
BE	0022627	cellular_component	cytosolic small ribosomal subunit
BF	0003735	molecular_function	structural constituent of ribosome
BF	0006412	biological_process	translation
BF	0019843	molecular_function	rRNA binding
BF	0022627	cellular_component	cytosolic small ribosomal subunit
BG	0006412	biological_process	translation
BH	0003729	molecular_function	mRNA binding
BH	0003735	molecular_function	structural constituent of ribosome
BH	0005840	cellular_component	ribosome
BH	0006412	biological_process	translation
BH	0019843	molecular_function	rRNA binding
BH	0022627	cellular_component	cytosolic small ribosomal subunit
BI	0003735	molecular_function	structural constituent of ribosome
BI	0006412	biological_process	translation
BI	0019843	molecular_function	rRNA binding
BI	0022627	cellular_component	cytosolic small ribosomal subunit
BJ	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BJ	0003723	molecular_function	RNA binding
BJ	0003735	molecular_function	structural constituent of ribosome
BJ	0006412	biological_process	translation
BJ	0022627	cellular_component	cytosolic small ribosomal subunit
BK	0002181	biological_process	cytoplasmic translation
BK	0003735	molecular_function	structural constituent of ribosome
BK	0006412	biological_process	translation
BK	0022627	cellular_component	cytosolic small ribosomal subunit
BL	0000049	molecular_function	tRNA binding
BL	0003735	molecular_function	structural constituent of ribosome
BL	0006412	biological_process	translation
BL	0022627	cellular_component	cytosolic small ribosomal subunit
BM	0003735	molecular_function	structural constituent of ribosome
BM	0006412	biological_process	translation
BM	0019843	molecular_function	rRNA binding
BM	0022627	cellular_component	cytosolic small ribosomal subunit
BN	0003735	molecular_function	structural constituent of ribosome
BN	0005840	cellular_component	ribosome
BN	0006412	biological_process	translation
BN	0019843	molecular_function	rRNA binding
BN	0022627	cellular_component	cytosolic small ribosomal subunit
BO	0003735	molecular_function	structural constituent of ribosome
BO	0005829	cellular_component	cytosol
BO	0006412	biological_process	translation
BO	0015935	cellular_component	small ribosomal subunit
BO	0019843	molecular_function	rRNA binding
BP	0002181	biological_process	cytoplasmic translation
BP	0003735	molecular_function	structural constituent of ribosome
BP	0006412	biological_process	translation
BP	0008270	molecular_function	zinc ion binding
BP	0019843	molecular_function	rRNA binding
BP	0022627	cellular_component	cytosolic small ribosomal subunit
BQ	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BQ	0003735	molecular_function	structural constituent of ribosome
BQ	0006412	biological_process	translation
BQ	0022627	cellular_component	cytosolic small ribosomal subunit
BR	0003735	molecular_function	structural constituent of ribosome
BR	0006412	biological_process	translation
BR	0019843	molecular_function	rRNA binding
BR	0022627	cellular_component	cytosolic small ribosomal subunit
BS	0003735	molecular_function	structural constituent of ribosome
BS	0005829	cellular_component	cytosol
BS	0006412	biological_process	translation
BS	0015935	cellular_component	small ribosomal subunit
BT	0003735	molecular_function	structural constituent of ribosome
BT	0006412	biological_process	translation
BT	0019843	molecular_function	rRNA binding
BT	0022627	cellular_component	cytosolic small ribosomal subunit
BU	0000028	biological_process	ribosomal small subunit assembly
BU	0003723	molecular_function	RNA binding
BU	0003735	molecular_function	structural constituent of ribosome
BU	0006412	biological_process	translation
BU	0022627	cellular_component	cytosolic small ribosomal subunit
BW	0002181	biological_process	cytoplasmic translation
BW	0003735	molecular_function	structural constituent of ribosome
BW	0006412	biological_process	translation
BW	0015935	cellular_component	small ribosomal subunit
BX	0003735	molecular_function	structural constituent of ribosome
BX	0006364	biological_process	rRNA processing
BX	0006412	biological_process	translation
BX	0008270	molecular_function	zinc ion binding
BX	0022627	cellular_component	cytosolic small ribosomal subunit
BY	0000028	biological_process	ribosomal small subunit assembly
BY	0003735	molecular_function	structural constituent of ribosome
BY	0006412	biological_process	translation
BY	0022627	cellular_component	cytosolic small ribosomal subunit
BY	0030490	biological_process	maturation of SSU-rRNA

Functional Information from PROSITE/UniProt

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AVVVrqkqefrrp.DGlhvsFedNamVI

Chain	Residue	Details
AH	ALA71-ILE97

site_id	PS00051
Number of Residues	17
Details	RIBOSOMAL_L39E Ribosomal protein L39e signature. KTnrkVvsHprrRHWRR

Chain	Residue	Details
Aa	LYS29-ARG45

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GalIVTTSsGVMsqyeAR

Chain	Residue	Details
BI	GLY100-ARG117

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. IrAFarA.GIrIgrieDvTPvPHD

Chain	Residue	Details
BM	ILE94-IAS116

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KqPNSAiR

Chain	Residue	Details
BN	LYS58-ARG65

site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDiVtIaEcRPIS

Chain	Residue	Details
BR	GLY83-SER95

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. NGKgfvsvdLqpemVGhrFGEFapT

Chain	Residue	Details
BT	ASN89-THR113

site_id	PS00358
Number of Residues	17
Details	RIBOSOMAL_L5 Ribosomal protein L5 signature. LrnITGQevVrCfAKrT

Chain	Residue	Details
AD	LEU29-THR45

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGiiGQanAvrtAvARGI

Chain	Residue	Details
BJ	GLY69-ILE87

site_id	PS00361
Number of Residues	16
Details	RIBOSOMAL_S10 Ribosomal protein S10 signature. AertGVnisGPVpLPT

Chain	Residue	Details
BL	ALA27-THR42

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. LrkHLsvnKkDvhNkrsLnlTeskirrLvkY

Chain	Residue	Details
BQ	LEU98-TYR128

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FkngtlvDtaAiTiGKGtqGpvkR

Chain	Residue	Details
AB	PHE193-ARG216

site_id	PS00475
Number of Residues	31
Details	RIBOSOMAL_L15 Ribosomal protein L15 signature. KVLGaGlLdhp..VtIaaltFSdsAfekIteaG

Chain	Residue	Details
AM	LYS73-GLY103
AI	LYS103-GLY133

site_id	PS00527
Number of Residues	22
Details	RIBOSOMAL_S14 Ribosomal protein S14 signature. R.Cgrkqglvrkyd.IYLCRhCFR

Chain	Residue	Details
BP	ARG17-ARG38

site_id	PS00528
Number of Residues	15
Details	RIBOSOMAL_S4E Ribosomal protein S4e signature. HqKRLSvPksWkVgK

Chain	Residue	Details
BE	HIS3-LYS17

site_id	PS00529
Number of Residues	23
Details	RIBOSOMAL_S24E Ribosomal protein S24e signature. YGmqESkGYAkVYADearmkqvE

Chain	Residue	Details
BW	TYR59-GLU81

site_id	PS00578
Number of Residues	12
Details	RIBOSOMAL_S6E Ribosomal protein S6e signature. ITGGcDgsGfVM

Chain	Residue	Details
BG	ILE52-MET63

site_id	PS00579
Number of Residues	15
Details	RIBOSOMAL_L29 Ribosomal protein L29 signature. NPGRIGeIRRTIARI

Chain	Residue	Details
AU	ASN43-ILE57

site_id	PS00580
Number of Residues	21
Details	RIBOSOMAL_L32E Ribosomal protein L32e signature. FkRtcshKfkRLddn..WRRprG

Chain	Residue	Details
AY	PHE22-GLY42

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GRrvkFrAtvIVGNrn.GyVGlGqakdv.QVgp.AI

Chain	Residue	Details
BF	GLY65-ILE97

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LErRLqtqVLRlglArTviqARqFI

Chain	Residue	Details
BD	LEU109-ILE133

site_id	PS00634
Number of Residues	33
Details	RIBOSOMAL_L30 Ribosomal protein L30 signature. TMkmLrLhKvnHcVfvpenphykgMVqkVkdYV

Chain	Residue	Details
AV	THR20-VAL52

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHerGlkVRGQ

Chain	Residue	Details
BO	ARG131-GLN144

site_id	PS00700
Number of Residues	22
Details	RIBOSOMAL_L6_2 Ribosomal protein L6 signature 2. QktkIkrFdpRiFqDGIYIvqK

Chain	Residue	Details
AE	GLN154-LYS175

site_id	PS00712
Number of Residues	16
Details	RIBOSOMAL_S17E Ribosomal protein S17e signature. IeSKiIRNrVAGYvTR

Chain	Residue	Details
BS	ILE41-ARG56

site_id	PS00783
Number of Residues	24
Details	RIBOSOMAL_L13 Ribosomal protein L13 signature. IRGMLPykrarGRdamsrLkVYvG

Chain	Residue	Details
AG	ILE80-GLY103

site_id	PS00939
Number of Residues	27
Details	RIBOSOMAL_L1E Ribosomal protein L1e signature. NtkeRryAIrSAIaATTdptlvslRGH

Chain	Residue	Details
AC	ASN106-HIS132

site_id	PS00962
Number of Residues	12
Details	RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. IdEYLAAGVHIG

Chain	Residue	Details
BB	ILE40-GLY51

site_id	PS00963
Number of Residues	25
Details	RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PdvIIVtDpagDaqvLkEassiGVP

Chain	Residue	Details
BB	PRO143-PRO167

site_id	PS00993
Number of Residues	21
Details	RIBOSOMAL_L30E_2 Ribosomal protein L30e signature 2. ELGPvcGKpftiaaMaIlDvG

Chain	Residue	Details
AW	GLU70-GLY90

site_id	PS01073
Number of Residues	18
Details	RIBOSOMAL_L24E Ribosomal protein L24e signature. FcGkmLePGtGklYvKkD

Chain	Residue	Details
AT	PHE8-ASP25

site_id	PS01077
Number of Residues	20
Details	RIBOSOMAL_L37E Ribosomal protein L37e signature. GTsSmGkRqkrt.HakCrRCG

Chain	Residue	Details
AZ	GLY4-GLY23

site_id	PS01082
Number of Residues	18
Details	RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. SeekkAPYifIkNQkeLG

Chain	Residue	Details
AF	SER68-GLY85

site_id	PS01106
Number of Residues	18
Details	RIBOSOMAL_L18E Ribosomal protein L18e signature. KrLeaPSrnYAaVNIsKI

Chain	Residue	Details
AM	LYS41-ILE58

site_id	PS01108
Number of Residues	18
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. GDtVkVMrGdfKGte.GkV

Chain	Residue	Details
AS	GLY50-VAL67

site_id	PS01144
Number of Residues	15
Details	RIBOSOMAL_L31E Ribosomal protein L31e signature. VKLDksINeHlWeKG

Chain	Residue	Details
AX	VAL49-GLY63

site_id	PS01168
Number of Residues	33
Details	RIBOSOMAL_S27E Ribosomal protein S27e signature. KCndCeneqiiFGsAsrkitCvvCGrtLaePtG

Chain	Residue	Details
BX	LYS16-GLY48

site_id	PS01171
Number of Residues	26
Details	RIBOSOMAL_L21E Ribosomal protein L21e signature. GQmVhididpsvqk.GmpNpkFqGsTG

Chain	Residue	Details
AP	GLY37-GLY62

site_id	PS01191
Number of Residues	13
Details	RIBOSOMAL_S3AE Ribosomal protein S3Ae signature. LvGRNvEtTVgEL

Chain	Residue	Details
BA	LEU43-LEU55

site_id	PS01193
Number of Residues	20
Details	RIBOSOMAL_S8E Ribosomal protein S8e signature. RkaTGGkvita.RgKrKfEMG

Chain	Residue	Details
BK	ARG9-GLY28

site_id	PS01194
Number of Residues	24
Details	RIBOSOMAL_L15E Ribosomal protein L15e signature. DRARsLGYkAkqGIVVVRvNVrRG

Chain	Residue	Details
AJ	ASP48-GLY71

site_id	PS01257
Number of Residues	22
Details	RIBOSOMAL_L10E Ribosomal protein L10e signature. ADRvssGMRrAFGKNvGtaARV

Chain	Residue	Details
AK	ALA106-VAL127

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI2
Number of Residues	233
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	60
Details	Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	12
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	30
Details	Zinc finger: {"description":"C4-type","evidences":[{"source":"HAMAP-Rule","id":"MF_00773","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00773","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	18
Details	Zinc finger: {"description":"C4-type","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	4
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	63
Details	Domain: {"description":"S4 RNA-binding","evidences":[{"source":"HAMAP-Rule","id":"MF_00485","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI15
Number of Residues	63
Details	Domain: {"description":"S5 DRBM","evidences":[{"source":"HAMAP-Rule","id":"MF_01307","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI16
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01364","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI18
Number of Residues	22
Details	Zinc finger: {"description":"C4-type","evidences":[{"source":"HAMAP-Rule","id":"MF_00371","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI19
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00371","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)