9ZJQ

Human KLK3 following acylation by CDD-3290

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002803	biological_process	positive regulation of antibacterial peptide production
A	0003073	biological_process	regulation of systemic arterial blood pressure
A	0004175	molecular_function	endopeptidase activity
A	0004252	molecular_function	serine-type endopeptidase activity
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005634	cellular_component	nucleus
A	0006508	biological_process	proteolysis
A	0008236	molecular_function	serine-type peptidase activity
A	0016525	biological_process	negative regulation of angiogenesis
A	0016811	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
A	0030141	cellular_component	secretory granule
A	0031638	biological_process	zymogen activation
A	0032991	cellular_component	protein-containing complex
A	0070062	cellular_component	extracellular exosome

Functional Information from PROSITE/UniProt

site_id	PS00134
Number of Residues	6
Details	TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC

Chain	Residue	Details
A	LEU61-CYS66

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site_id	PS00135
Number of Residues	12
Details	TRYPSIN_SER Serine proteases, trypsin family, serine active site. STcsGDSGGPLV

Chain	Residue	Details
A	SER207-VAL218

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	233
Details	Domain: {"description":"Peptidase S1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00274","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	3
Details	Active site: {"description":"Charge relay system","evidences":[{"source":"PubMed","id":"18187150","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine"}

Chain

Residue

Details

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