9ZAW
HMG-CoA synthase 1 (HMGCS1) bound to inhibitor compound CNP7
This is a non-PDB format compatible entry.
Functional Information from PROSITE/UniProt
| site_id | PS01226 |
| Number of Residues | 16 |
| Details | HMG_COA_SYNTHASE Hydroxymethylglutaryl-coenzyme A synthase active site. NtDIEGIDttNACYgG |
| Chain | Residue | Details |
| A | ASN117-GLY132 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU10116","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Acyl-thioester intermediate"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P54868","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20346956","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2P8U","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
