9Z8F
Destabilized open state sheep connexin-46 in DMPC nanodiscs at neutral pH
Functional Information from PROSITE/UniProt
| site_id | PS00018 |
| Number of Residues | 13 |
| Details | EF_HAND_1 EF-hand calcium-binding domain. DSDGEGAVTavEL |
| Chain | Residue | Details |
| A | ASP370-LEU382 |
| site_id | PS00407 |
| Number of Residues | 14 |
| Details | CONNEXINS_1 Connexins signature 1. CNTqQPGCenVCYD |
| Chain | Residue | Details |
| A | CYS54-ASP67 |
| site_id | PS00408 |
| Number of Residues | 17 |
| Details | CONNEXINS_2 Connexins signature 2. Cdrw.PCpntVDCFISRP |
| Chain | Residue | Details |
| A | CYS178-PRO194 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 156 |
| Details | Intramembrane: {"evidences":[{"source":"PubMed","id":"30542154","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 36 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"30542154","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 960 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"30542154","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 684 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"30542154","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
