9YO4
Crystal structure of integrin a4b1 headpiece in complex with MR128 (Mn)
This is a non-PDB format compatible entry.
Functional Information from PROSITE/UniProt
| site_id | PS00022 |
| Number of Residues | 12 |
| Details | EGF_1 EGF-like domain signature 1. CrCneGrvGRhC |
| Chain | Residue | Details |
| B | CYS469-CYS480 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 238 |
| Details | Domain: {"description":"VWFA","evidences":[{"source":"PubMed","id":"22451694","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"33962943","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Region: {"description":"CX3CL1-binding","evidences":[{"source":"PubMed","id":"23125415","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 19 |
| Details | Region: {"description":"CX3CL1-binding","evidences":[{"source":"PubMed","id":"24789099","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 10 |
| Details | Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"in MIDAS binding site","evidences":[{"source":"PubMed","id":"22451694","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33962943","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3VI3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3VI4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NXD","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Binding site: {"description":"in MIDAS binding site","evidences":[{"source":"PubMed","id":"22451694","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3VI4","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | Binding site: {"description":"in ADMIDAS binding site","evidences":[{"source":"PubMed","id":"22451694","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33962943","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3VI3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NXD","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Binding site: {"description":"in LIMBS binding site","evidences":[{"source":"PubMed","id":"22451694","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3VI3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3VI4","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 3 |
| Details | Binding site: {"description":"in LIMBS binding site","evidences":[{"source":"PubMed","id":"22451694","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33962943","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3VI3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3VI4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NXD","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 3 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"22451694","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33962943","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3VI3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3VI4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NWL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NXD","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"33962943","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NWL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NXD","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33962943","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NXD","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
