9YA1

Cryo-EM structure of intraconoidal microtubule 2 (ICMT2) from Toxoplasma gondii (8-nm repeat)

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0005200	molecular_function	structural constituent of cytoskeleton
1	0005856	cellular_component	cytoskeleton
1	0007010	biological_process	cytoskeleton organization
2	0005200	molecular_function	structural constituent of cytoskeleton
2	0005856	cellular_component	cytoskeleton
2	0007010	biological_process	cytoskeleton organization
a	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
a	0005634	cellular_component	nucleus
a	0030178	biological_process	negative regulation of Wnt signaling pathway
a	0031397	biological_process	negative regulation of protein ubiquitination
a	0098869	biological_process	cellular oxidant detoxification
A	0005856	cellular_component	cytoskeleton
A	0008017	molecular_function	microtubule binding
A0	0003924	molecular_function	GTPase activity
A0	0005856	cellular_component	cytoskeleton
A0	0007010	biological_process	cytoskeleton organization
A1	0005525	molecular_function	GTP binding
A1	0005856	cellular_component	cytoskeleton
A1	0007010	biological_process	cytoskeleton organization
A2	0003924	molecular_function	GTPase activity
A2	0005856	cellular_component	cytoskeleton
A2	0007010	biological_process	cytoskeleton organization
A3	0005525	molecular_function	GTP binding
A3	0005856	cellular_component	cytoskeleton
A3	0007010	biological_process	cytoskeleton organization
A4	0003924	molecular_function	GTPase activity
A4	0005856	cellular_component	cytoskeleton
A4	0007010	biological_process	cytoskeleton organization
A5	0005525	molecular_function	GTP binding
A5	0005856	cellular_component	cytoskeleton
A5	0007010	biological_process	cytoskeleton organization
A6	0003924	molecular_function	GTPase activity
A6	0005856	cellular_component	cytoskeleton
A6	0007010	biological_process	cytoskeleton organization
A7	0005525	molecular_function	GTP binding
A7	0005856	cellular_component	cytoskeleton
A7	0007010	biological_process	cytoskeleton organization
A8	0003924	molecular_function	GTPase activity
A8	0005856	cellular_component	cytoskeleton
A8	0007010	biological_process	cytoskeleton organization
A9	0005525	molecular_function	GTP binding
A9	0005856	cellular_component	cytoskeleton
A9	0007010	biological_process	cytoskeleton organization
b	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
b	0005634	cellular_component	nucleus
b	0030178	biological_process	negative regulation of Wnt signaling pathway
b	0031397	biological_process	negative regulation of protein ubiquitination
b	0098869	biological_process	cellular oxidant detoxification
B	0005856	cellular_component	cytoskeleton
B	0008017	molecular_function	microtubule binding
B0	0003924	molecular_function	GTPase activity
B0	0005856	cellular_component	cytoskeleton
B0	0007010	biological_process	cytoskeleton organization
B1	0005525	molecular_function	GTP binding
B1	0005856	cellular_component	cytoskeleton
B1	0007010	biological_process	cytoskeleton organization
B2	0003924	molecular_function	GTPase activity
B2	0005856	cellular_component	cytoskeleton
B2	0007010	biological_process	cytoskeleton organization
B3	0005525	molecular_function	GTP binding
B3	0005856	cellular_component	cytoskeleton
B3	0007010	biological_process	cytoskeleton organization
B4	0003924	molecular_function	GTPase activity
B4	0005856	cellular_component	cytoskeleton
B4	0007010	biological_process	cytoskeleton organization
B5	0005525	molecular_function	GTP binding
B5	0005856	cellular_component	cytoskeleton
B5	0007010	biological_process	cytoskeleton organization
B6	0003924	molecular_function	GTPase activity
B6	0005856	cellular_component	cytoskeleton
B6	0007010	biological_process	cytoskeleton organization
B7	0005525	molecular_function	GTP binding
B7	0005856	cellular_component	cytoskeleton
B7	0007010	biological_process	cytoskeleton organization
B8	0003924	molecular_function	GTPase activity
B8	0005856	cellular_component	cytoskeleton
B8	0007010	biological_process	cytoskeleton organization
B9	0005525	molecular_function	GTP binding
B9	0005856	cellular_component	cytoskeleton
B9	0007010	biological_process	cytoskeleton organization
c	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
c	0005634	cellular_component	nucleus
c	0030178	biological_process	negative regulation of Wnt signaling pathway
c	0031397	biological_process	negative regulation of protein ubiquitination
c	0098869	biological_process	cellular oxidant detoxification
C	0005856	cellular_component	cytoskeleton
C	0008017	molecular_function	microtubule binding
C0	0003924	molecular_function	GTPase activity
C0	0005856	cellular_component	cytoskeleton
C0	0007010	biological_process	cytoskeleton organization
C1	0005525	molecular_function	GTP binding
C1	0005856	cellular_component	cytoskeleton
C1	0007010	biological_process	cytoskeleton organization
C2	0003924	molecular_function	GTPase activity
C2	0005856	cellular_component	cytoskeleton
C2	0007010	biological_process	cytoskeleton organization
C3	0005525	molecular_function	GTP binding
C3	0005856	cellular_component	cytoskeleton
C3	0007010	biological_process	cytoskeleton organization
C4	0003924	molecular_function	GTPase activity
C4	0005856	cellular_component	cytoskeleton
C4	0007010	biological_process	cytoskeleton organization
C5	0005525	molecular_function	GTP binding
C5	0005856	cellular_component	cytoskeleton
C5	0007010	biological_process	cytoskeleton organization
C6	0003924	molecular_function	GTPase activity
C6	0005856	cellular_component	cytoskeleton
C6	0007010	biological_process	cytoskeleton organization
C7	0005525	molecular_function	GTP binding
C7	0005856	cellular_component	cytoskeleton
C7	0007010	biological_process	cytoskeleton organization
C8	0003924	molecular_function	GTPase activity
C8	0005856	cellular_component	cytoskeleton
C8	0007010	biological_process	cytoskeleton organization
C9	0005525	molecular_function	GTP binding
C9	0005856	cellular_component	cytoskeleton
C9	0007010	biological_process	cytoskeleton organization
d	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
d	0005634	cellular_component	nucleus
d	0030178	biological_process	negative regulation of Wnt signaling pathway
d	0031397	biological_process	negative regulation of protein ubiquitination
d	0098869	biological_process	cellular oxidant detoxification
D	0005856	cellular_component	cytoskeleton
D	0008017	molecular_function	microtubule binding
D0	0003924	molecular_function	GTPase activity
D0	0005856	cellular_component	cytoskeleton
D0	0007010	biological_process	cytoskeleton organization
D1	0005525	molecular_function	GTP binding
D1	0005856	cellular_component	cytoskeleton
D1	0007010	biological_process	cytoskeleton organization
D2	0003924	molecular_function	GTPase activity
D2	0005856	cellular_component	cytoskeleton
D2	0007010	biological_process	cytoskeleton organization
D3	0005525	molecular_function	GTP binding
D3	0005856	cellular_component	cytoskeleton
D3	0007010	biological_process	cytoskeleton organization
D4	0003924	molecular_function	GTPase activity
D4	0005856	cellular_component	cytoskeleton
D4	0007010	biological_process	cytoskeleton organization
D5	0005525	molecular_function	GTP binding
D5	0005856	cellular_component	cytoskeleton
D5	0007010	biological_process	cytoskeleton organization
D6	0003924	molecular_function	GTPase activity
D6	0005856	cellular_component	cytoskeleton
D6	0007010	biological_process	cytoskeleton organization
D7	0005525	molecular_function	GTP binding
D7	0005856	cellular_component	cytoskeleton
D7	0007010	biological_process	cytoskeleton organization
D8	0003924	molecular_function	GTPase activity
D8	0005856	cellular_component	cytoskeleton
D8	0007010	biological_process	cytoskeleton organization
D9	0005525	molecular_function	GTP binding
D9	0005856	cellular_component	cytoskeleton
D9	0007010	biological_process	cytoskeleton organization
e	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
e	0005634	cellular_component	nucleus
e	0030178	biological_process	negative regulation of Wnt signaling pathway
e	0031397	biological_process	negative regulation of protein ubiquitination
e	0098869	biological_process	cellular oxidant detoxification
E	0005856	cellular_component	cytoskeleton
E	0008017	molecular_function	microtubule binding
E0	0003924	molecular_function	GTPase activity
E0	0005856	cellular_component	cytoskeleton
E0	0007010	biological_process	cytoskeleton organization
E1	0005525	molecular_function	GTP binding
E1	0005856	cellular_component	cytoskeleton
E1	0007010	biological_process	cytoskeleton organization
E2	0003924	molecular_function	GTPase activity
E2	0005856	cellular_component	cytoskeleton
E2	0007010	biological_process	cytoskeleton organization
E3	0005525	molecular_function	GTP binding
E3	0005856	cellular_component	cytoskeleton
E3	0007010	biological_process	cytoskeleton organization
E4	0003924	molecular_function	GTPase activity
E4	0005856	cellular_component	cytoskeleton
E4	0007010	biological_process	cytoskeleton organization
E5	0005525	molecular_function	GTP binding
E5	0005856	cellular_component	cytoskeleton
E5	0007010	biological_process	cytoskeleton organization
E6	0003924	molecular_function	GTPase activity
E6	0005856	cellular_component	cytoskeleton
E6	0007010	biological_process	cytoskeleton organization
E7	0005525	molecular_function	GTP binding
E7	0005856	cellular_component	cytoskeleton
E7	0007010	biological_process	cytoskeleton organization
E8	0003924	molecular_function	GTPase activity
E8	0005856	cellular_component	cytoskeleton
E8	0007010	biological_process	cytoskeleton organization
E9	0005525	molecular_function	GTP binding
E9	0005856	cellular_component	cytoskeleton
E9	0007010	biological_process	cytoskeleton organization
f	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
f	0005634	cellular_component	nucleus
f	0030178	biological_process	negative regulation of Wnt signaling pathway
f	0031397	biological_process	negative regulation of protein ubiquitination
f	0098869	biological_process	cellular oxidant detoxification
F	0005856	cellular_component	cytoskeleton
F	0008017	molecular_function	microtubule binding
F0	0003924	molecular_function	GTPase activity
F0	0005856	cellular_component	cytoskeleton
F0	0007010	biological_process	cytoskeleton organization
F1	0005525	molecular_function	GTP binding
F1	0005856	cellular_component	cytoskeleton
F1	0007010	biological_process	cytoskeleton organization
g	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
g	0005634	cellular_component	nucleus
g	0030178	biological_process	negative regulation of Wnt signaling pathway
g	0031397	biological_process	negative regulation of protein ubiquitination
g	0098869	biological_process	cellular oxidant detoxification
G	0005856	cellular_component	cytoskeleton
G	0008017	molecular_function	microtubule binding
h	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
h	0005634	cellular_component	nucleus
h	0030178	biological_process	negative regulation of Wnt signaling pathway
h	0031397	biological_process	negative regulation of protein ubiquitination
h	0098869	biological_process	cellular oxidant detoxification
H	0005856	cellular_component	cytoskeleton
H	0008017	molecular_function	microtubule binding
i	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
i	0005634	cellular_component	nucleus
i	0030178	biological_process	negative regulation of Wnt signaling pathway
i	0031397	biological_process	negative regulation of protein ubiquitination
i	0098869	biological_process	cellular oxidant detoxification
I	0005856	cellular_component	cytoskeleton
I	0008017	molecular_function	microtubule binding
j	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
j	0005634	cellular_component	nucleus
j	0030178	biological_process	negative regulation of Wnt signaling pathway
j	0031397	biological_process	negative regulation of protein ubiquitination
j	0098869	biological_process	cellular oxidant detoxification
J	0005856	cellular_component	cytoskeleton
J	0008017	molecular_function	microtubule binding
k	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
k	0005634	cellular_component	nucleus
k	0030178	biological_process	negative regulation of Wnt signaling pathway
k	0031397	biological_process	negative regulation of protein ubiquitination
k	0098869	biological_process	cellular oxidant detoxification
K	0005856	cellular_component	cytoskeleton
K	0008017	molecular_function	microtubule binding
l	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
l	0005634	cellular_component	nucleus
l	0030178	biological_process	negative regulation of Wnt signaling pathway
l	0031397	biological_process	negative regulation of protein ubiquitination
l	0098869	biological_process	cellular oxidant detoxification
m	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
m	0005634	cellular_component	nucleus
m	0030178	biological_process	negative regulation of Wnt signaling pathway
m	0031397	biological_process	negative regulation of protein ubiquitination
m	0098869	biological_process	cellular oxidant detoxification
n	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
n	0005634	cellular_component	nucleus
n	0030178	biological_process	negative regulation of Wnt signaling pathway
n	0031397	biological_process	negative regulation of protein ubiquitination
n	0098869	biological_process	cellular oxidant detoxification
o	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
o	0005634	cellular_component	nucleus
o	0030178	biological_process	negative regulation of Wnt signaling pathway
o	0031397	biological_process	negative regulation of protein ubiquitination
o	0098869	biological_process	cellular oxidant detoxification
p	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
p	0005634	cellular_component	nucleus
p	0030178	biological_process	negative regulation of Wnt signaling pathway
p	0031397	biological_process	negative regulation of protein ubiquitination
p	0098869	biological_process	cellular oxidant detoxification
q	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
q	0005634	cellular_component	nucleus
q	0030178	biological_process	negative regulation of Wnt signaling pathway
q	0031397	biological_process	negative regulation of protein ubiquitination
q	0098869	biological_process	cellular oxidant detoxification
r	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
r	0005634	cellular_component	nucleus
r	0030178	biological_process	negative regulation of Wnt signaling pathway
r	0031397	biological_process	negative regulation of protein ubiquitination
r	0098869	biological_process	cellular oxidant detoxification
s	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
s	0005634	cellular_component	nucleus
s	0030178	biological_process	negative regulation of Wnt signaling pathway
s	0031397	biological_process	negative regulation of protein ubiquitination
s	0098869	biological_process	cellular oxidant detoxification
t	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
t	0005634	cellular_component	nucleus
t	0030178	biological_process	negative regulation of Wnt signaling pathway
t	0031397	biological_process	negative regulation of protein ubiquitination
t	0098869	biological_process	cellular oxidant detoxification
u	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
u	0005634	cellular_component	nucleus
u	0030178	biological_process	negative regulation of Wnt signaling pathway
u	0031397	biological_process	negative regulation of protein ubiquitination
u	0098869	biological_process	cellular oxidant detoxification
v	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
v	0005634	cellular_component	nucleus
v	0030178	biological_process	negative regulation of Wnt signaling pathway
v	0031397	biological_process	negative regulation of protein ubiquitination
v	0098869	biological_process	cellular oxidant detoxification
w	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
w	0005634	cellular_component	nucleus
w	0030178	biological_process	negative regulation of Wnt signaling pathway
w	0031397	biological_process	negative regulation of protein ubiquitination
w	0098869	biological_process	cellular oxidant detoxification
x	0004791	molecular_function	thioredoxin-disulfide reductase (NADPH) activity
x	0005634	cellular_component	nucleus
x	0030178	biological_process	negative regulation of Wnt signaling pathway
x	0031397	biological_process	negative regulation of protein ubiquitination
x	0098869	biological_process	cellular oxidant detoxification

Functional Information from PROSITE/UniProt

site_id	PS00227
Number of Residues	7
Details	TUBULIN Tubulin subunits alpha, beta, and gamma signature. GGGTGSG

Chain	Residue	Details
C2	GLY142-GLY148
C1	GLY140-GLY146

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site_id	PS00228
Number of Residues	4
Details	TUBULIN_B_AUTOREG Tubulin-beta mRNA autoregulation signal. MREI

Chain	Residue	Details
C1	MET1-ILE4

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	26
Details	Active site: {"evidences":[{"source":"UniProtKB","id":"P68363","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	182
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P68363","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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