9Y7V

Structure of Mycobacterium tuberculosis pyruvate dehydrogenase complex E2p core subunit DlaT bound to coenzyme A in a hexamer state

Functional Information from GO Data

Chain	GOid	namespace	contents
D	0004148	molecular_function	dihydrolipoyl dehydrogenase (NADH) activity
D	0004149	molecular_function	dihydrolipoyllysine-residue succinyltransferase activity
D	0004591	molecular_function	oxoglutarate dehydrogenase (succinyl-transferring) activity
D	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
D	0005515	molecular_function	protein binding
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0006099	biological_process	tricarboxylic acid cycle
D	0015036	molecular_function	disulfide oxidoreductase activity
D	0031405	molecular_function	lipoic acid binding
D	0045254	cellular_component	pyruvate dehydrogenase complex
D	0045454	biological_process	cell redox homeostasis
D	1990748	biological_process	cellular detoxification
E	0004148	molecular_function	dihydrolipoyl dehydrogenase (NADH) activity
E	0004149	molecular_function	dihydrolipoyllysine-residue succinyltransferase activity
E	0004591	molecular_function	oxoglutarate dehydrogenase (succinyl-transferring) activity
E	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
E	0005515	molecular_function	protein binding
E	0005829	cellular_component	cytosol
E	0005886	cellular_component	plasma membrane
E	0006099	biological_process	tricarboxylic acid cycle
E	0015036	molecular_function	disulfide oxidoreductase activity
E	0031405	molecular_function	lipoic acid binding
E	0045254	cellular_component	pyruvate dehydrogenase complex
E	0045454	biological_process	cell redox homeostasis
E	1990748	biological_process	cellular detoxification
F	0004148	molecular_function	dihydrolipoyl dehydrogenase (NADH) activity
F	0004149	molecular_function	dihydrolipoyllysine-residue succinyltransferase activity
F	0004591	molecular_function	oxoglutarate dehydrogenase (succinyl-transferring) activity
F	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
F	0005515	molecular_function	protein binding
F	0005829	cellular_component	cytosol
F	0005886	cellular_component	plasma membrane
F	0006099	biological_process	tricarboxylic acid cycle
F	0015036	molecular_function	disulfide oxidoreductase activity
F	0031405	molecular_function	lipoic acid binding
F	0045254	cellular_component	pyruvate dehydrogenase complex
F	0045454	biological_process	cell redox homeostasis
F	1990748	biological_process	cellular detoxification

Functional Information from PROSITE/UniProt

site_id	PS00189
Number of Residues	30
Details	LIPOYL 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. GdtVeldEPLveVSTdKVDteIpspaaGvL

Chain	Residue	Details
D	GLY27-LEU56
D	GLY146-LEU175

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Active site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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