9Y17
WT human DNA polymerase beta, Binary complex templating dT
Functional Information from PROSITE/UniProt
| site_id | PS00522 |
| Number of Residues | 20 |
| Details | DNA_POLYMERASE_X DNA polymerase family X signature. GSFrRGaesSgDMDVLLthP |
| Chain | Residue | Details |
| A | GLY179-PRO198 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 9 |
| Details | Region: {"description":"DNA-binding"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile; Schiff-base intermediate with DNA; for 5'-dRP lyase activity","evidences":[{"source":"PubMed","id":"9572863","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12517346","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8841120","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9287163","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1BPX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BPZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MQ3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ZQO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ZQQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"8841119","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8ICW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8ICX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8ICY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"8841119","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8ICX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"9287163","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1BPY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q8K409","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Omega-N-methylarginine; by PRMT6","evidences":[{"source":"PubMed","id":"16600869","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"19713937","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21362556","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
