Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

9XAJ

Cryo-EM structure of the pre-40S ribosome (Enp1-Rrp12 Mut) from Chaetomium thermophilum, state Rrp12-A1*

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0005634	cellular_component	nucleus
1	0005730	cellular_component	nucleolus
1	0005737	cellular_component	cytoplasm
1	0006364	biological_process	rRNA processing
1	0016435	molecular_function	rRNA (guanine) methyltransferase activity
1	0070476	biological_process	rRNA (guanine-N7)-methylation
2	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
2	0000479	biological_process	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
2	0003924	molecular_function	GTPase activity
2	0005525	molecular_function	GTP binding
2	0005730	cellular_component	nucleolus
2	0030688	cellular_component	preribosome, small subunit precursor
2	0034511	molecular_function	U3 snoRNA binding
3	0005634	cellular_component	nucleus
3	0005730	cellular_component	nucleolus
3	0005737	cellular_component	cytoplasm
4	0005730	cellular_component	nucleolus
4	0005737	cellular_component	cytoplasm
4	0006364	biological_process	rRNA processing
4	0030515	molecular_function	snoRNA binding
4	0030688	cellular_component	preribosome, small subunit precursor
5	0000056	biological_process	ribosomal small subunit export from nucleus
5	0005634	cellular_component	nucleus
5	0005829	cellular_component	cytosol
5	0030688	cellular_component	preribosome, small subunit precursor
5	0042274	biological_process	ribosomal small subunit biogenesis
6	0004674	molecular_function	protein serine/threonine kinase activity
6	0005737	cellular_component	cytoplasm
6	0016887	molecular_function	ATP hydrolysis activity
6	0106310	molecular_function	protein serine kinase activity
7	0005634	cellular_component	nucleus
8	0005730	cellular_component	nucleolus
8	0032040	cellular_component	small-subunit processome
b	0005737	cellular_component	cytoplasm
E	0003735	molecular_function	structural constituent of ribosome
E	0005737	cellular_component	cytoplasm
E	0006412	biological_process	translation
E	0022627	cellular_component	cytosolic small ribosomal subunit
f	0000028	biological_process	ribosomal small subunit assembly
f	0003735	molecular_function	structural constituent of ribosome
f	0022627	cellular_component	cytosolic small ribosomal subunit
f	0030490	biological_process	maturation of SSU-rRNA
H	0002181	biological_process	cytoplasmic translation
H	0003723	molecular_function	RNA binding
H	0003735	molecular_function	structural constituent of ribosome
H	0006412	biological_process	translation
H	0019843	molecular_function	rRNA binding
H	0022627	cellular_component	cytosolic small ribosomal subunit
i	0005737	cellular_component	cytoplasm
i	0031386	molecular_function	protein tag activity
K	0006364	biological_process	rRNA processing
K	0022627	cellular_component	cytosolic small ribosomal subunit
K	0030686	cellular_component	90S preribosome
K	0032040	cellular_component	small-subunit processome
K	0042274	biological_process	ribosomal small subunit biogenesis
M	0003735	molecular_function	structural constituent of ribosome
M	0015935	cellular_component	small ribosomal subunit
M	0019843	molecular_function	rRNA binding
M	0022627	cellular_component	cytosolic small ribosomal subunit
M	0042274	biological_process	ribosomal small subunit biogenesis
M	0043226	cellular_component	organelle
O	0003735	molecular_function	structural constituent of ribosome
O	0022627	cellular_component	cytosolic small ribosomal subunit
P	0015935	cellular_component	small ribosomal subunit
P	0022626	cellular_component	cytosolic ribosome
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005730	cellular_component	nucleolus
Q	0022627	cellular_component	cytosolic small ribosomal subunit
Q	0070181	molecular_function	small ribosomal subunit rRNA binding
S	0000028	biological_process	ribosomal small subunit assembly
S	0003735	molecular_function	structural constituent of ribosome
S	0022627	cellular_component	cytosolic small ribosomal subunit
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0015935	cellular_component	small ribosomal subunit
W	0000028	biological_process	ribosomal small subunit assembly
W	0003723	molecular_function	RNA binding
W	0003735	molecular_function	structural constituent of ribosome
W	0022627	cellular_component	cytosolic small ribosomal subunit
Z	0022627	cellular_component	cytosolic small ribosomal subunit

Functional Information from PROSITE/UniProt

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. ErLtnsLMmhgrnnGKKlmavrIVahA

Chain	Residue	Details
I	GLU78-ALA104

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GyvILTTSaGIMdheeAR

Chain	Residue	Details
Z	GLY100-ARG117

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. LrALarS.GMkIgrieDvTPtPSD

Chain	Residue	Details
R	LEU115-ASP137

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KqPNSAiR

Chain	Residue	Details
a	LYS62-ARG69

site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDmVvVgQcRPLS

Chain	Residue	Details
O	GLY125-SER137

site_id	PS00109
Number of Residues	13
Details	PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. LVHgDLSEYNILY

Chain	Residue	Details
6	LEU277-TYR289

site_id	PS00299
Number of Residues	26
Details	UBIQUITIN_1 Ubiquitin domain signature. KskIqDkegIPpdqQrLIFaGkqleD

Chain	Residue	Details
i	LYS27-ASP52

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. SGKefnqveIkpemVGhyLGEFsiT

Chain	Residue	Details
S	SER106-THR130

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGhtSQvyAvrqAiAKSI

Chain	Residue	Details
T	GLY71-ILE89

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. VrkHLernRkDkdSkfrLilIesrihrLarY

Chain	Residue	Details
Q	VAL98-TYR128

site_id	PS00528
Number of Residues	15
Details	RIBOSOMAL_S4E Ribosomal protein S4e signature. HqKRLSaPshWlLdK

Chain	Residue	Details
H	HIS8-LYS22

site_id	PS00529
Number of Residues	23
Details	RIBOSOMAL_S24E Ribosomal protein S24e signature. YGggKTtGFAlIYDSpealkkfE

Chain	Residue	Details
b	TYR67-GLU89

site_id	PS00578
Number of Residues	12
Details	RIBOSOMAL_S6E Ribosomal protein S6e signature. ITGGnDkqGfPM

Chain	Residue	Details
J	ILE52-MET63

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LErRLqtlVYKlglAkSihhARvLI

Chain	Residue	Details
M	LEU103-ILE127

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHywGlrVRGQ

Chain	Residue	Details
V	ARG123-GLN136

site_id	PS00948
Number of Residues	14
Details	RIBOSOMAL_S7E Ribosomal protein S7e signature. RLtRELEKKFSdRH

Chain	Residue	Details
K	ARG82-HIS95

site_id	PS00961
Number of Residues	9
Details	RIBOSOMAL_S28E Ribosomal protein S28e signature. ESEREARrL

Chain	Residue	Details
f	GLU59-LEU67

site_id	PS01189
Number of Residues	19
Details	RIBOSOMAL_S12E Ribosomal protein S12e signature. ALKgvLklSlmhDGLarGL

Chain	Residue	Details
P	ALA29-LEU47

site_id	PS01191
Number of Residues	13
Details	RIBOSOMAL_S3AE Ribosomal protein S3Ae signature. LkGRIfEvCLaDL

Chain	Residue	Details
E	LEU61-LEU73

site_id	PS01245
Number of Residues	12
Details	RIO1 RIO1/ZK632.3/MJ0444 family signature. LVHGDLSEYNiL

Chain	Residue	Details
6	LEU277-LEU288

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI17
Number of Residues	52
Details	Domain: {"description":"KH","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)