9X2A
Cryo-EM structure of PsoA in cofactor bound state (PsoA-PKS-II)
This is a non-PDB format compatible entry.
Functional Information from PROSITE/UniProt
| site_id | PS00061 |
| Number of Residues | 29 |
| Details | ADH_SHORT Short-chain dehydrogenases/reductases family signature. LaafhppidgSdgYVASKWASeVFLeKVQ |
| Chain | Residue | Details |
| A | LEU3832-GLN3860 |
| site_id | PS00211 |
| Number of Residues | 15 |
| Details | ABC_TRANSPORTER_1 ABC transporters family signature. LSLGQSRLYFLSQYM |
| Chain | Residue | Details |
| A | LEU2591-MET2605 |
| site_id | PS00455 |
| Number of Residues | 12 |
| Details | AMP_BINDING Putative AMP-binding domain signature. ILYTSGSTGsPK |
| Chain | Residue | Details |
| A | ILE3198-LYS3209 |
| site_id | PS00606 |
| Number of Residues | 17 |
| Details | KS3_1 Ketosynthase family 3 (KS3) active site signature. GPSisVDtACSSSlaAV |
| Chain | Residue | Details |
| A | GLY173-VAL189 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 872 |
| Details | Domain: {"description":"Ketosynthase family 3 (KS3)","evidences":[{"source":"PROSITE-ProRule","id":"PRU01348","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 614 |
| Details | Domain: {"description":"PKS/mFAS DH","evidences":[{"source":"PROSITE-ProRule","id":"PRU01363","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 644 |
| Details | Region: {"description":"Malonyl-CoA:ACP transacylase (MAT) domain","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 356 |
| Details | Region: {"description":"Dehydratase (DH) domain","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 272 |
| Details | Region: {"description":"N-terminal hotdog fold","evidences":[{"source":"PROSITE-ProRule","id":"PRU01363","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 312 |
| Details | Region: {"description":"C-terminal hotdog fold","evidences":[{"source":"PROSITE-ProRule","id":"PRU01363","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 348 |
| Details | Region: {"description":"Ketoreductase (KR) domain","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 6 |
| Details | Active site: {"description":"For beta-ketoacyl synthase activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU01348","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor; for dehydratase activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU01363","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor; for dehydratase activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU01363","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
