9W3O
Crystal Structure of Human rhinovirus A2 3C Protease in Complex with a Broad-spectrum Inhibitor
This is a non-PDB format compatible entry.
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Active site: {"description":"For protease 3C activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU01222","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 477 |
| Chain | Residue | Details |
| A | HIS40 | electrostatic stabiliser, proton shuttle (general acid/base) |
| A | GLU71 | electrostatic stabiliser, modifies pKa |
| A | GLY145 | electrostatic stabiliser |
| A | CYS147 | electrostatic stabiliser |
| site_id | MCSA2 |
| Number of Residues | 4 |
| Details | M-CSA 477 |
| Chain | Residue | Details |
| B | HIS40 | electrostatic stabiliser, proton shuttle (general acid/base) |
| B | GLU71 | electrostatic stabiliser, modifies pKa |
| B | GLY145 | electrostatic stabiliser |
| B | CYS147 | electrostatic stabiliser |
