9VUK

Cryo-EM structure of the human measles virus RNA-dependent RNA polymerase complex

Functional Information from GO Data

Chain	GOid	namespace	contents
L	0000166	molecular_function	nucleotide binding
L	0001172	biological_process	RNA-templated transcription
L	0003824	molecular_function	catalytic activity
L	0003924	molecular_function	GTPase activity
L	0003968	molecular_function	RNA-directed RNA polymerase activity
L	0005524	molecular_function	ATP binding
L	0006370	biological_process	7-methylguanosine mRNA capping
L	0006397	biological_process	mRNA processing
L	0008168	molecular_function	methyltransferase activity
L	0016740	molecular_function	transferase activity
L	0016779	molecular_function	nucleotidyltransferase activity
L	0016787	molecular_function	hydrolase activity
L	0030430	cellular_component	host cell cytoplasm
L	0034062	molecular_function	5'-3' RNA polymerase activity
L	0046872	molecular_function	metal ion binding
L	0062105	molecular_function	RNA 2'-O-methyltransferase activity
L	0106005	biological_process	RNA 5'-cap (guanine-N7)-methylation

Functional Information from PROSITE/UniProt

site_id	PS01037
Number of Residues	18
Details	SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN

Chain	Residue	Details
A	PRO24-ASN41

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	46
Details	Region: {"description":"Interaction with the L polymerase","evidences":[{"source":"UniProtKB","id":"Q9WMB4","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	184
Details	Domain: {"description":"RdRp catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU00539","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q997F0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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