Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

9VMX

Human PIEZO1-E756del-MDFIC

Functional Information from PROSITE/UniProt

site_id	PS00022
Number of Residues	12
Details	EGF_1 EGF-like domain signature 1. CcCcgDemGDdC

Chain	Residue	Details
C	CYS202-CYS213

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YQCVAAH

Chain	Residue	Details
A	TYR1680-HIS1686

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	60
Details	Transmembrane: {"description":"Helical; Name=13"}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	3
Details	Topological domain: {"description":"Extracellular"}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	60
Details	Transmembrane: {"description":"Helical; Name=14"}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	27
Details	Topological domain: {"description":"Cytoplasmic"}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	48
Details	Transmembrane: {"description":"Helical; Name=16"}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	33
Details	Transmembrane: {"description":"Helical; Name=17","evidences":[{"source":"UniProtKB","id":"E2JF22","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	30
Details	Topological domain: {"description":"Extracellular","evidences":[{"source":"UniProtKB","id":"E2JF22","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	39
Details	Transmembrane: {"description":"Helical; Name=18","evidences":[{"source":"UniProtKB","id":"E2JF22","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	672
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"UniProtKB","id":"E2JF22","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	42
Details	Transmembrane: {"description":"Helical; Name=19","evidences":[{"source":"UniProtKB","id":"E2JF22","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	81
Details	Transmembrane: {"description":"Helical; Name=20","evidences":[{"source":"UniProtKB","id":"E2JF22","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	45
Details	Transmembrane: {"description":"Helical; Name=21","evidences":[{"source":"UniProtKB","id":"E2JF22","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	45
Details	Transmembrane: {"description":"Helical; Name=22","evidences":[{"source":"UniProtKB","id":"E2JF22","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	45
Details	Transmembrane: {"description":"Helical; Name=23","evidences":[{"source":"UniProtKB","id":"E2JF22","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI15
Number of Residues	63
Details	Transmembrane: {"description":"Helical; Name=24","evidences":[{"source":"UniProtKB","id":"E2JF22","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI16
Number of Residues	78
Details	Transmembrane: {"description":"Helical; Name=25","evidences":[{"source":"UniProtKB","id":"E2JF22","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI17
Number of Residues	54
Details	Transmembrane: {"description":"Helical; Name=26","evidences":[{"source":"UniProtKB","id":"E2JF22","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI18
Number of Residues	48
Details	Transmembrane: {"description":"Helical; Name=28","evidences":[{"source":"UniProtKB","id":"E2JF22","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI19
Number of Residues	129
Details	Transmembrane: {"description":"Helical; Name=29","evidences":[{"source":"UniProtKB","id":"E2JF22","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI20
Number of Residues	45
Details	Transmembrane: {"description":"Helical; Name=30","evidences":[{"source":"UniProtKB","id":"E2JF22","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI21
Number of Residues	54
Details	Transmembrane: {"description":"Helical; Name=31","evidences":[{"source":"UniProtKB","id":"E2JF22","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI22
Number of Residues	63
Details	Transmembrane: {"description":"Helical; Name=32","evidences":[{"source":"UniProtKB","id":"E2JF22","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI23
Number of Residues	57
Details	Transmembrane: {"description":"Helical; Name=33","evidences":[{"source":"UniProtKB","id":"E2JF22","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI24
Number of Residues	48
Details	Transmembrane: {"description":"Helical; Name=34","evidences":[{"source":"UniProtKB","id":"E2JF22","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI25
Number of Residues	45
Details	Transmembrane: {"description":"Helical; Name=36","evidences":[{"source":"UniProtKB","id":"E2JF22","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI26
Number of Residues	60
Details	Transmembrane: {"description":"Helical; Name=37","evidences":[{"source":"UniProtKB","id":"E2JF22","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI27
Number of Residues	60
Details	Transmembrane: {"description":"Helical; Name=38","evidences":[{"source":"UniProtKB","id":"E2JF22","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI28
Number of Residues	87
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI29
Number of Residues	3
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI30
Number of Residues	3
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)