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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

9VLV

Crystal structure of bovine Adenosine Deaminase in complex with EHNA

Functional Information from PROSITE/UniProt
site_idPS00485
Number of Residues7
DetailsA_DEAMINASE Adenosine and AMP deaminase signature. SLNTDDP
ChainResidueDetails
ASER291-PRO297
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsActive site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"P03958","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues4
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"12554940","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14709046","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15139750","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15213224","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15239652","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15695814","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16033254","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16060665","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18549808","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1KRM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1NDV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1NDW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1NDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1NDZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1O5R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QXL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1VFL","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues1
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"12554940","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14709046","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15139750","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15239652","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16033254","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16060665","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18549808","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1NDW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1NDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1NDZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1O5R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QXL","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues1
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"14709046","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16060665","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1NDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1WXY","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues1
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"12554940","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14709046","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15139750","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15239652","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16033254","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18549808","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1NDW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1NDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1NDZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1O5R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QXL","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues2
DetailsSite: {"description":"Important for interaction with adenosine receptors and increasing their affinity for agonists","evidences":[{"source":"UniProtKB","id":"P00813","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI7
Number of Residues1
DetailsSite: {"description":"Important for catalytic activity","evidences":[{"source":"UniProtKB","id":"P03958","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails
site_idSWS_FT_FI8
Number of Residues2
DetailsModified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P00813","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

257629

PDB entries from 2026-08-05

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