Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

9VKW

Cryo-EM structure of the NuA3 complex bound to Ace-coenzyme A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000781	cellular_component	chromosome, telomeric region
A	0000785	cellular_component	chromatin
A	0003682	molecular_function	chromatin binding
A	0003712	molecular_function	transcription coregulator activity
A	0004402	molecular_function	histone acetyltransferase activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0006351	biological_process	DNA-templated transcription
A	0006357	biological_process	regulation of transcription by RNA polymerase II
A	0008270	molecular_function	zinc ion binding
A	0030466	biological_process	silent mating-type cassette heterochromatin formation
A	0031507	biological_process	heterochromatin formation
A	0031509	biological_process	subtelomeric heterochromatin formation
A	0033100	cellular_component	NuA3 histone acetyltransferase complex
A	0061733	molecular_function	protein-lysine-acetyltransferase activity
A	0070775	cellular_component	H3 histone acetyltransferase complex
A	1990467	cellular_component	NuA3a histone acetyltransferase complex
A	1990468	cellular_component	NuA3b histone acetyltransferase complex
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0006338	biological_process	chromatin remodeling
B	0006351	biological_process	DNA-templated transcription
B	0006357	biological_process	regulation of transcription by RNA polymerase II
B	0008270	molecular_function	zinc ion binding
B	0033100	cellular_component	NuA3 histone acetyltransferase complex
B	0140003	molecular_function	histone H3K36me3 reader activity
B	0140566	molecular_function	histone reader activity
B	1990467	cellular_component	NuA3a histone acetyltransferase complex
B	1990468	cellular_component	NuA3b histone acetyltransferase complex
C	0000785	cellular_component	chromatin
C	0004402	molecular_function	histone acetyltransferase activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0006325	biological_process	chromatin organization
C	0006338	biological_process	chromatin remodeling
C	0006351	biological_process	DNA-templated transcription
C	0008270	molecular_function	zinc ion binding
C	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
C	0033100	cellular_component	NuA3 histone acetyltransferase complex
C	0140002	molecular_function	histone H3K4me3 reader activity
C	1990467	cellular_component	NuA3a histone acetyltransferase complex
D	0000123	cellular_component	histone acetyltransferase complex
D	0004402	molecular_function	histone acetyltransferase activity
D	0005634	cellular_component	nucleus
D	0006281	biological_process	DNA repair
D	0006338	biological_process	chromatin remodeling
D	0006351	biological_process	DNA-templated transcription
D	0033100	cellular_component	NuA3 histone acetyltransferase complex
D	0035267	cellular_component	NuA4 histone acetyltransferase complex
D	1990467	cellular_component	NuA3a histone acetyltransferase complex
D	1990468	cellular_component	NuA3b histone acetyltransferase complex
E	0000785	cellular_component	chromatin
E	0003677	molecular_function	DNA binding
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005669	cellular_component	transcription factor TFIID complex
E	0005674	cellular_component	transcription factor TFIIF complex
E	0006281	biological_process	DNA repair
E	0006338	biological_process	chromatin remodeling
E	0006351	biological_process	DNA-templated transcription
E	0006355	biological_process	regulation of DNA-templated transcription
E	0006357	biological_process	regulation of transcription by RNA polymerase II
E	0006366	biological_process	transcription by RNA polymerase II
E	0006367	biological_process	transcription initiation at RNA polymerase II promoter
E	0010468	biological_process	regulation of gene expression
E	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
E	0016514	cellular_component	SWI/SNF complex
E	0016592	cellular_component	mediator complex
E	0031011	cellular_component	Ino80 complex
E	0032991	cellular_component	protein-containing complex
E	0033100	cellular_component	NuA3 histone acetyltransferase complex
E	0042393	molecular_function	histone binding
E	0045944	biological_process	positive regulation of transcription by RNA polymerase II
E	0051123	biological_process	RNA polymerase II preinitiation complex assembly
E	1990467	cellular_component	NuA3a histone acetyltransferase complex
E	1990468	cellular_component	NuA3b histone acetyltransferase complex

Functional Information from PROSITE/UniProt

site_id	PS01359
Number of Residues	45
Details	ZF_PHD_1 Zinc finger PHD-type signature. CavClgtdsdnlnti..................................VfCdg..Cdia.VHqeCygiifipegk...................................WlCrrC

Chain	Residue	Details
B	CYS266-CYS310

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	25
Details	Zinc finger: {"description":"C2HC MYST-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU01063","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"UniProtKB","id":"Q9H7Z6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9H7Z6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine; by autocatalysis","evidences":[{"source":"UniProtKB","id":"Q9H7Z6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	50
Details	Zinc finger: {"description":"PHD-type 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00146","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	33
Details	Zinc finger: {"description":"C2HC pre-PHD-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU01146","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	65
Details	Zinc finger: {"description":"PHD-type 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01146","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"22106047","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)