9V7Y

Crystal structure of class II HMG-CoA reductase from Ruegeria pomeroyi(Silicibacter pomeroyi))

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004420	molecular_function	hydroxymethylglutaryl-CoA reductase (NADPH) activity
A	0140643	molecular_function	hydroxymethylglutaryl-CoA reductase (NADH) activity
B	0004420	molecular_function	hydroxymethylglutaryl-CoA reductase (NADPH) activity
B	0140643	molecular_function	hydroxymethylglutaryl-CoA reductase (NADH) activity
C	0004420	molecular_function	hydroxymethylglutaryl-CoA reductase (NADPH) activity
C	0140643	molecular_function	hydroxymethylglutaryl-CoA reductase (NADH) activity
D	0004420	molecular_function	hydroxymethylglutaryl-CoA reductase (NADPH) activity
D	0140643	molecular_function	hydroxymethylglutaryl-CoA reductase (NADH) activity
E	0004420	molecular_function	hydroxymethylglutaryl-CoA reductase (NADPH) activity
E	0140643	molecular_function	hydroxymethylglutaryl-CoA reductase (NADH) activity
F	0004420	molecular_function	hydroxymethylglutaryl-CoA reductase (NADPH) activity
F	0140643	molecular_function	hydroxymethylglutaryl-CoA reductase (NADH) activity

Functional Information from PROSITE/UniProt

site_id	PS00066
Number of Residues	15
Details	HMG_COA_REDUCTASE_1 Hydroxymethylglutaryl-coenzyme A reductases signature 1. HlIVdVRDaMGaNtV

Chain	Residue	Details
A	HIS185-VAL199

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site_id	PS00318
Number of Residues	8
Details	HMG_COA_REDUCTASE_2 Hydroxymethylglutaryl-coenzyme A reductases signature 2. LGlVGGAT

Chain	Residue	Details
A	LEU334-THR341

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site_id	PS01192
Number of Residues	14
Details	HMG_COA_REDUCTASE_3 Hydroxymethylglutaryl-coenzyme A reductases signature 3. ALaTegIqRGHMtL

Chain	Residue	Details
A	ALA380-LEU393

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