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9UZP

Cryo-EM Structure of the Vaccinia Virus Entry/Fusion Complex (EFC) Including the F9 Subunit

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0003677molecular_functionDNA binding
A0004386molecular_functionhelicase activity
A0005524molecular_functionATP binding
A0006353biological_processDNA-templated transcription termination
A0016787molecular_functionhydrolase activity
A0019031cellular_componentviral envelope
A0039663biological_processmembrane fusion involved in viral entry into host cell
A0046718biological_processsymbiont entry into host cell
A0055036cellular_componentvirion membrane
B0019031cellular_componentviral envelope
B0019064biological_processfusion of virus membrane with host plasma membrane
B0039663biological_processmembrane fusion involved in viral entry into host cell
B0046718biological_processsymbiont entry into host cell
B0055036cellular_componentvirion membrane
c0005515molecular_functionprotein binding
c0019031cellular_componentviral envelope
c0039663biological_processmembrane fusion involved in viral entry into host cell
c0046718biological_processsymbiont entry into host cell
c0055036cellular_componentvirion membrane
C0005515molecular_functionprotein binding
C0019031cellular_componentviral envelope
C0039663biological_processmembrane fusion involved in viral entry into host cell
C0046718biological_processsymbiont entry into host cell
C0055036cellular_componentvirion membrane
d0005515molecular_functionprotein binding
d0019031cellular_componentviral envelope
d0019064biological_processfusion of virus membrane with host plasma membrane
d0039663biological_processmembrane fusion involved in viral entry into host cell
d0044167cellular_componenthost cell endoplasmic reticulum membrane
d0046718biological_processsymbiont entry into host cell
d0055036cellular_componentvirion membrane
D0005515molecular_functionprotein binding
D0019031cellular_componentviral envelope
D0019064biological_processfusion of virus membrane with host plasma membrane
D0039663biological_processmembrane fusion involved in viral entry into host cell
D0044167cellular_componenthost cell endoplasmic reticulum membrane
D0046718biological_processsymbiont entry into host cell
D0055036cellular_componentvirion membrane
e0019031cellular_componentviral envelope
e0019064biological_processfusion of virus membrane with host plasma membrane
e0039663biological_processmembrane fusion involved in viral entry into host cell
e0046718biological_processsymbiont entry into host cell
e0055036cellular_componentvirion membrane
E0019031cellular_componentviral envelope
E0019064biological_processfusion of virus membrane with host plasma membrane
E0039663biological_processmembrane fusion involved in viral entry into host cell
E0046718biological_processsymbiont entry into host cell
E0055036cellular_componentvirion membrane
f0019031cellular_componentviral envelope
f0019064biological_processfusion of virus membrane with host plasma membrane
f0039663biological_processmembrane fusion involved in viral entry into host cell
f0046718biological_processsymbiont entry into host cell
f0055036cellular_componentvirion membrane
F0019031cellular_componentviral envelope
F0019064biological_processfusion of virus membrane with host plasma membrane
F0039663biological_processmembrane fusion involved in viral entry into host cell
F0046718biological_processsymbiont entry into host cell
F0055036cellular_componentvirion membrane
G0019031cellular_componentviral envelope
G0055036cellular_componentvirion membrane
I0019031cellular_componentviral envelope
I0019064biological_processfusion of virus membrane with host plasma membrane
I0039663biological_processmembrane fusion involved in viral entry into host cell
I0046718biological_processsymbiont entry into host cell
I0055036cellular_componentvirion membrane
j0019031cellular_componentviral envelope
j0039663biological_processmembrane fusion involved in viral entry into host cell
j0046718biological_processsymbiont entry into host cell
j0055036cellular_componentvirion membrane
J0019031cellular_componentviral envelope
J0039663biological_processmembrane fusion involved in viral entry into host cell
J0046718biological_processsymbiont entry into host cell
J0055036cellular_componentvirion membrane
k0019031cellular_componentviral envelope
k0046718biological_processsymbiont entry into host cell
k0055036cellular_componentvirion membrane
K0019031cellular_componentviral envelope
K0046718biological_processsymbiont entry into host cell
K0055036cellular_componentvirion membrane
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues40
DetailsTransmembrane: {"description":"Helical; Signal-anchor for type II membrane protein","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues1070
DetailsTopological domain: {"description":"Virion surface","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues120
DetailsTransmembrane: {"description":"Helical; Signal-anchor for type III membrane protein","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues40
DetailsTransmembrane: {"description":"Helical; Signal-anchor","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI5
Number of Residues110
DetailsTopological domain: {"description":"Virion surface","evidences":[{"evidenceCode":"ECO:0000305"}]}
ChainResidueDetails

site_idSWS_FT_FI6
Number of Residues40
DetailsTransmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

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PDB entries from 2026-03-25

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