9UTP
Cryo-EM structure of the oxytocin receptor bound to nanobody Nb2B11
Functional Information from PROSITE/UniProt
| site_id | PS00237 |
| Number of Residues | 17 |
| Details | G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. ASTyLLLLMSLDRCLaI |
| Chain | Residue | Details |
| A | ALA125-ILE141 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 30 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"32832646","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35241813","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35851571","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6TPK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7QVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RYC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 25 |
| Details | Transmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"32832646","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35241813","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35851571","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6TPK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7QVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RYC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 40 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"32832646","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35241813","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35851571","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6TPK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7QVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RYC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 30 |
| Details | Transmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"32832646","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35241813","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35851571","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6TPK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7QVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RYC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=4","evidences":[{"source":"PubMed","id":"32832646","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35241813","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35851571","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6TPK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7QVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RYC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 23 |
| Details | Transmembrane: {"description":"Helical; Name=6","evidences":[{"source":"PubMed","id":"32832646","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35241813","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35851571","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6TPK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7QVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RYC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=7","evidences":[{"source":"PubMed","id":"32832646","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35241813","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"35851571","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6TPK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7QVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7RYC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"35241813","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7RYC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"32832646","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6TPK","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
