9UNL

Cryo-EM structure of the human prohibitin complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000122	biological_process	negative regulation of transcription by RNA polymerase II
A	0001649	biological_process	osteoblast differentiation
A	0001850	molecular_function	complement component C3a binding
A	0001851	molecular_function	complement component C3b binding
A	0002639	biological_process	positive regulation of immunoglobulin production
A	0003714	molecular_function	transcription corepressor activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0005769	cellular_component	early endosome
A	0005886	cellular_component	plasma membrane
A	0006355	biological_process	regulation of DNA-templated transcription
A	0007005	biological_process	mitochondrion organization
A	0007165	biological_process	signal transduction
A	0008285	biological_process	negative regulation of cell population proliferation
A	0009986	cellular_component	cell surface
A	0010628	biological_process	positive regulation of gene expression
A	0010944	biological_process	negative regulation of transcription by competitive promoter binding
A	0016020	cellular_component	membrane
A	0019899	molecular_function	enzyme binding
A	0030308	biological_process	negative regulation of cell growth
A	0031871	molecular_function	proteinase activated receptor binding
A	0032740	biological_process	positive regulation of interleukin-17 production
A	0035632	cellular_component	mitochondrial prohibitin complex
A	0039529	biological_process	RIG-I signaling pathway
A	0040029	biological_process	epigenetic regulation of gene expression
A	0042113	biological_process	B cell activation
A	0042177	biological_process	negative regulation of protein catabolic process
A	0042826	molecular_function	histone deacetylase binding
A	0042981	biological_process	regulation of apoptotic process
A	0043525	biological_process	positive regulation of neuron apoptotic process
A	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
A	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0045893	biological_process	positive regulation of DNA-templated transcription
A	0045917	biological_process	positive regulation of complement activation
A	0046718	biological_process	symbiont entry into host cell
A	0046982	molecular_function	protein heterodimerization activity
A	0048661	biological_process	positive regulation of smooth muscle cell proliferation
A	0050821	biological_process	protein stabilization
A	0050847	biological_process	progesterone receptor signaling pathway
A	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
A	0060766	biological_process	negative regulation of androgen receptor signaling pathway
A	0070062	cellular_component	extracellular exosome
A	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
A	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
A	0071354	biological_process	cellular response to interleukin-6
A	0071897	biological_process	DNA biosynthetic process
A	0072538	biological_process	T-helper 17 type immune response
A	0140374	biological_process	antiviral innate immune response
A	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
A	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
B	0000423	biological_process	mitophagy
B	0002639	biological_process	positive regulation of immunoglobulin production
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005741	cellular_component	mitochondrial outer membrane
B	0005743	cellular_component	mitochondrial inner membrane
B	0005886	cellular_component	plasma membrane
B	0006351	biological_process	DNA-templated transcription
B	0006357	biological_process	regulation of transcription by RNA polymerase II
B	0006606	biological_process	protein import into nucleus
B	0007005	biological_process	mitochondrion organization
B	0007062	biological_process	sister chromatid cohesion
B	0009986	cellular_component	cell surface
B	0016363	cellular_component	nuclear matrix
B	0016477	biological_process	cell migration
B	0030331	molecular_function	nuclear estrogen receptor binding
B	0030449	biological_process	regulation of complement activation
B	0032991	cellular_component	protein-containing complex
B	0033218	molecular_function	amide binding
B	0035632	cellular_component	mitochondrial prohibitin complex
B	0039529	biological_process	RIG-I signaling pathway
B	0042113	biological_process	B cell activation
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0043066	biological_process	negative regulation of apoptotic process
B	0043410	biological_process	positive regulation of MAPK cascade
B	0045892	biological_process	negative regulation of DNA-templated transcription
B	0046625	molecular_function	sphingolipid binding
B	0046982	molecular_function	protein heterodimerization activity
B	0050821	biological_process	protein stabilization
B	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
B	0071944	cellular_component	cell periphery
B	0098800	cellular_component	inner mitochondrial membrane protein complex
B	0140374	biological_process	antiviral innate immune response
B	1900208	biological_process	regulation of cardiolipin metabolic process
B	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
C	0000122	biological_process	negative regulation of transcription by RNA polymerase II
C	0001649	biological_process	osteoblast differentiation
C	0001850	molecular_function	complement component C3a binding
C	0001851	molecular_function	complement component C3b binding
C	0002639	biological_process	positive regulation of immunoglobulin production
C	0003714	molecular_function	transcription corepressor activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0005769	cellular_component	early endosome
C	0005886	cellular_component	plasma membrane
C	0006355	biological_process	regulation of DNA-templated transcription
C	0007005	biological_process	mitochondrion organization
C	0007165	biological_process	signal transduction
C	0008285	biological_process	negative regulation of cell population proliferation
C	0009986	cellular_component	cell surface
C	0010628	biological_process	positive regulation of gene expression
C	0010944	biological_process	negative regulation of transcription by competitive promoter binding
C	0016020	cellular_component	membrane
C	0019899	molecular_function	enzyme binding
C	0030308	biological_process	negative regulation of cell growth
C	0031871	molecular_function	proteinase activated receptor binding
C	0032740	biological_process	positive regulation of interleukin-17 production
C	0035632	cellular_component	mitochondrial prohibitin complex
C	0039529	biological_process	RIG-I signaling pathway
C	0040029	biological_process	epigenetic regulation of gene expression
C	0042113	biological_process	B cell activation
C	0042177	biological_process	negative regulation of protein catabolic process
C	0042826	molecular_function	histone deacetylase binding
C	0042981	biological_process	regulation of apoptotic process
C	0043525	biological_process	positive regulation of neuron apoptotic process
C	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
C	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
C	0045892	biological_process	negative regulation of DNA-templated transcription
C	0045893	biological_process	positive regulation of DNA-templated transcription
C	0045917	biological_process	positive regulation of complement activation
C	0046718	biological_process	symbiont entry into host cell
C	0046982	molecular_function	protein heterodimerization activity
C	0048661	biological_process	positive regulation of smooth muscle cell proliferation
C	0050821	biological_process	protein stabilization
C	0050847	biological_process	progesterone receptor signaling pathway
C	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
C	0060766	biological_process	negative regulation of androgen receptor signaling pathway
C	0070062	cellular_component	extracellular exosome
C	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
C	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
C	0071354	biological_process	cellular response to interleukin-6
C	0071897	biological_process	DNA biosynthetic process
C	0072538	biological_process	T-helper 17 type immune response
C	0140374	biological_process	antiviral innate immune response
C	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
C	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
D	0000423	biological_process	mitophagy
D	0002639	biological_process	positive regulation of immunoglobulin production
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005741	cellular_component	mitochondrial outer membrane
D	0005743	cellular_component	mitochondrial inner membrane
D	0005886	cellular_component	plasma membrane
D	0006351	biological_process	DNA-templated transcription
D	0006357	biological_process	regulation of transcription by RNA polymerase II
D	0006606	biological_process	protein import into nucleus
D	0007005	biological_process	mitochondrion organization
D	0007062	biological_process	sister chromatid cohesion
D	0009986	cellular_component	cell surface
D	0016363	cellular_component	nuclear matrix
D	0016477	biological_process	cell migration
D	0030331	molecular_function	nuclear estrogen receptor binding
D	0030449	biological_process	regulation of complement activation
D	0032991	cellular_component	protein-containing complex
D	0033218	molecular_function	amide binding
D	0035632	cellular_component	mitochondrial prohibitin complex
D	0039529	biological_process	RIG-I signaling pathway
D	0042113	biological_process	B cell activation
D	0042802	molecular_function	identical protein binding
D	0042803	molecular_function	protein homodimerization activity
D	0043066	biological_process	negative regulation of apoptotic process
D	0043410	biological_process	positive regulation of MAPK cascade
D	0045892	biological_process	negative regulation of DNA-templated transcription
D	0046625	molecular_function	sphingolipid binding
D	0046982	molecular_function	protein heterodimerization activity
D	0050821	biological_process	protein stabilization
D	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
D	0071944	cellular_component	cell periphery
D	0098800	cellular_component	inner mitochondrial membrane protein complex
D	0140374	biological_process	antiviral innate immune response
D	1900208	biological_process	regulation of cardiolipin metabolic process
D	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
E	0000122	biological_process	negative regulation of transcription by RNA polymerase II
E	0001649	biological_process	osteoblast differentiation
E	0001850	molecular_function	complement component C3a binding
E	0001851	molecular_function	complement component C3b binding
E	0002639	biological_process	positive regulation of immunoglobulin production
E	0003714	molecular_function	transcription corepressor activity
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0005743	cellular_component	mitochondrial inner membrane
E	0005769	cellular_component	early endosome
E	0005886	cellular_component	plasma membrane
E	0006355	biological_process	regulation of DNA-templated transcription
E	0007005	biological_process	mitochondrion organization
E	0007165	biological_process	signal transduction
E	0008285	biological_process	negative regulation of cell population proliferation
E	0009986	cellular_component	cell surface
E	0010628	biological_process	positive regulation of gene expression
E	0010944	biological_process	negative regulation of transcription by competitive promoter binding
E	0016020	cellular_component	membrane
E	0019899	molecular_function	enzyme binding
E	0030308	biological_process	negative regulation of cell growth
E	0031871	molecular_function	proteinase activated receptor binding
E	0032740	biological_process	positive regulation of interleukin-17 production
E	0035632	cellular_component	mitochondrial prohibitin complex
E	0039529	biological_process	RIG-I signaling pathway
E	0040029	biological_process	epigenetic regulation of gene expression
E	0042113	biological_process	B cell activation
E	0042177	biological_process	negative regulation of protein catabolic process
E	0042826	molecular_function	histone deacetylase binding
E	0042981	biological_process	regulation of apoptotic process
E	0043525	biological_process	positive regulation of neuron apoptotic process
E	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
E	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
E	0045892	biological_process	negative regulation of DNA-templated transcription
E	0045893	biological_process	positive regulation of DNA-templated transcription
E	0045917	biological_process	positive regulation of complement activation
E	0046718	biological_process	symbiont entry into host cell
E	0046982	molecular_function	protein heterodimerization activity
E	0048661	biological_process	positive regulation of smooth muscle cell proliferation
E	0050821	biological_process	protein stabilization
E	0050847	biological_process	progesterone receptor signaling pathway
E	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
E	0060766	biological_process	negative regulation of androgen receptor signaling pathway
E	0070062	cellular_component	extracellular exosome
E	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
E	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
E	0071354	biological_process	cellular response to interleukin-6
E	0071897	biological_process	DNA biosynthetic process
E	0072538	biological_process	T-helper 17 type immune response
E	0140374	biological_process	antiviral innate immune response
E	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
E	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
F	0000423	biological_process	mitophagy
F	0002639	biological_process	positive regulation of immunoglobulin production
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005737	cellular_component	cytoplasm
F	0005739	cellular_component	mitochondrion
F	0005741	cellular_component	mitochondrial outer membrane
F	0005743	cellular_component	mitochondrial inner membrane
F	0005886	cellular_component	plasma membrane
F	0006351	biological_process	DNA-templated transcription
F	0006357	biological_process	regulation of transcription by RNA polymerase II
F	0006606	biological_process	protein import into nucleus
F	0007005	biological_process	mitochondrion organization
F	0007062	biological_process	sister chromatid cohesion
F	0009986	cellular_component	cell surface
F	0016363	cellular_component	nuclear matrix
F	0016477	biological_process	cell migration
F	0030331	molecular_function	nuclear estrogen receptor binding
F	0030449	biological_process	regulation of complement activation
F	0032991	cellular_component	protein-containing complex
F	0033218	molecular_function	amide binding
F	0035632	cellular_component	mitochondrial prohibitin complex
F	0039529	biological_process	RIG-I signaling pathway
F	0042113	biological_process	B cell activation
F	0042802	molecular_function	identical protein binding
F	0042803	molecular_function	protein homodimerization activity
F	0043066	biological_process	negative regulation of apoptotic process
F	0043410	biological_process	positive regulation of MAPK cascade
F	0045892	biological_process	negative regulation of DNA-templated transcription
F	0046625	molecular_function	sphingolipid binding
F	0046982	molecular_function	protein heterodimerization activity
F	0050821	biological_process	protein stabilization
F	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
F	0071944	cellular_component	cell periphery
F	0098800	cellular_component	inner mitochondrial membrane protein complex
F	0140374	biological_process	antiviral innate immune response
F	1900208	biological_process	regulation of cardiolipin metabolic process
F	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
G	0000122	biological_process	negative regulation of transcription by RNA polymerase II
G	0001649	biological_process	osteoblast differentiation
G	0001850	molecular_function	complement component C3a binding
G	0001851	molecular_function	complement component C3b binding
G	0002639	biological_process	positive regulation of immunoglobulin production
G	0003714	molecular_function	transcription corepressor activity
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005737	cellular_component	cytoplasm
G	0005739	cellular_component	mitochondrion
G	0005743	cellular_component	mitochondrial inner membrane
G	0005769	cellular_component	early endosome
G	0005886	cellular_component	plasma membrane
G	0006355	biological_process	regulation of DNA-templated transcription
G	0007005	biological_process	mitochondrion organization
G	0007165	biological_process	signal transduction
G	0008285	biological_process	negative regulation of cell population proliferation
G	0009986	cellular_component	cell surface
G	0010628	biological_process	positive regulation of gene expression
G	0010944	biological_process	negative regulation of transcription by competitive promoter binding
G	0016020	cellular_component	membrane
G	0019899	molecular_function	enzyme binding
G	0030308	biological_process	negative regulation of cell growth
G	0031871	molecular_function	proteinase activated receptor binding
G	0032740	biological_process	positive regulation of interleukin-17 production
G	0035632	cellular_component	mitochondrial prohibitin complex
G	0039529	biological_process	RIG-I signaling pathway
G	0040029	biological_process	epigenetic regulation of gene expression
G	0042113	biological_process	B cell activation
G	0042177	biological_process	negative regulation of protein catabolic process
G	0042826	molecular_function	histone deacetylase binding
G	0042981	biological_process	regulation of apoptotic process
G	0043525	biological_process	positive regulation of neuron apoptotic process
G	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
G	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
G	0045892	biological_process	negative regulation of DNA-templated transcription
G	0045893	biological_process	positive regulation of DNA-templated transcription
G	0045917	biological_process	positive regulation of complement activation
G	0046718	biological_process	symbiont entry into host cell
G	0046982	molecular_function	protein heterodimerization activity
G	0048661	biological_process	positive regulation of smooth muscle cell proliferation
G	0050821	biological_process	protein stabilization
G	0050847	biological_process	progesterone receptor signaling pathway
G	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
G	0060766	biological_process	negative regulation of androgen receptor signaling pathway
G	0070062	cellular_component	extracellular exosome
G	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
G	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
G	0071354	biological_process	cellular response to interleukin-6
G	0071897	biological_process	DNA biosynthetic process
G	0072538	biological_process	T-helper 17 type immune response
G	0140374	biological_process	antiviral innate immune response
G	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
G	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
H	0000423	biological_process	mitophagy
H	0002639	biological_process	positive regulation of immunoglobulin production
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005737	cellular_component	cytoplasm
H	0005739	cellular_component	mitochondrion
H	0005741	cellular_component	mitochondrial outer membrane
H	0005743	cellular_component	mitochondrial inner membrane
H	0005886	cellular_component	plasma membrane
H	0006351	biological_process	DNA-templated transcription
H	0006357	biological_process	regulation of transcription by RNA polymerase II
H	0006606	biological_process	protein import into nucleus
H	0007005	biological_process	mitochondrion organization
H	0007062	biological_process	sister chromatid cohesion
H	0009986	cellular_component	cell surface
H	0016363	cellular_component	nuclear matrix
H	0016477	biological_process	cell migration
H	0030331	molecular_function	nuclear estrogen receptor binding
H	0030449	biological_process	regulation of complement activation
H	0032991	cellular_component	protein-containing complex
H	0033218	molecular_function	amide binding
H	0035632	cellular_component	mitochondrial prohibitin complex
H	0039529	biological_process	RIG-I signaling pathway
H	0042113	biological_process	B cell activation
H	0042802	molecular_function	identical protein binding
H	0042803	molecular_function	protein homodimerization activity
H	0043066	biological_process	negative regulation of apoptotic process
H	0043410	biological_process	positive regulation of MAPK cascade
H	0045892	biological_process	negative regulation of DNA-templated transcription
H	0046625	molecular_function	sphingolipid binding
H	0046982	molecular_function	protein heterodimerization activity
H	0050821	biological_process	protein stabilization
H	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
H	0071944	cellular_component	cell periphery
H	0098800	cellular_component	inner mitochondrial membrane protein complex
H	0140374	biological_process	antiviral innate immune response
H	1900208	biological_process	regulation of cardiolipin metabolic process
H	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
I	0000122	biological_process	negative regulation of transcription by RNA polymerase II
I	0001649	biological_process	osteoblast differentiation
I	0001850	molecular_function	complement component C3a binding
I	0001851	molecular_function	complement component C3b binding
I	0002639	biological_process	positive regulation of immunoglobulin production
I	0003714	molecular_function	transcription corepressor activity
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005737	cellular_component	cytoplasm
I	0005739	cellular_component	mitochondrion
I	0005743	cellular_component	mitochondrial inner membrane
I	0005769	cellular_component	early endosome
I	0005886	cellular_component	plasma membrane
I	0006355	biological_process	regulation of DNA-templated transcription
I	0007005	biological_process	mitochondrion organization
I	0007165	biological_process	signal transduction
I	0008285	biological_process	negative regulation of cell population proliferation
I	0009986	cellular_component	cell surface
I	0010628	biological_process	positive regulation of gene expression
I	0010944	biological_process	negative regulation of transcription by competitive promoter binding
I	0016020	cellular_component	membrane
I	0019899	molecular_function	enzyme binding
I	0030308	biological_process	negative regulation of cell growth
I	0031871	molecular_function	proteinase activated receptor binding
I	0032740	biological_process	positive regulation of interleukin-17 production
I	0035632	cellular_component	mitochondrial prohibitin complex
I	0039529	biological_process	RIG-I signaling pathway
I	0040029	biological_process	epigenetic regulation of gene expression
I	0042113	biological_process	B cell activation
I	0042177	biological_process	negative regulation of protein catabolic process
I	0042826	molecular_function	histone deacetylase binding
I	0042981	biological_process	regulation of apoptotic process
I	0043525	biological_process	positive regulation of neuron apoptotic process
I	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
I	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
I	0045892	biological_process	negative regulation of DNA-templated transcription
I	0045893	biological_process	positive regulation of DNA-templated transcription
I	0045917	biological_process	positive regulation of complement activation
I	0046718	biological_process	symbiont entry into host cell
I	0046982	molecular_function	protein heterodimerization activity
I	0048661	biological_process	positive regulation of smooth muscle cell proliferation
I	0050821	biological_process	protein stabilization
I	0050847	biological_process	progesterone receptor signaling pathway
I	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
I	0060766	biological_process	negative regulation of androgen receptor signaling pathway
I	0070062	cellular_component	extracellular exosome
I	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
I	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
I	0071354	biological_process	cellular response to interleukin-6
I	0071897	biological_process	DNA biosynthetic process
I	0072538	biological_process	T-helper 17 type immune response
I	0140374	biological_process	antiviral innate immune response
I	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
I	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
J	0000423	biological_process	mitophagy
J	0002639	biological_process	positive regulation of immunoglobulin production
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005737	cellular_component	cytoplasm
J	0005739	cellular_component	mitochondrion
J	0005741	cellular_component	mitochondrial outer membrane
J	0005743	cellular_component	mitochondrial inner membrane
J	0005886	cellular_component	plasma membrane
J	0006351	biological_process	DNA-templated transcription
J	0006357	biological_process	regulation of transcription by RNA polymerase II
J	0006606	biological_process	protein import into nucleus
J	0007005	biological_process	mitochondrion organization
J	0007062	biological_process	sister chromatid cohesion
J	0009986	cellular_component	cell surface
J	0016363	cellular_component	nuclear matrix
J	0016477	biological_process	cell migration
J	0030331	molecular_function	nuclear estrogen receptor binding
J	0030449	biological_process	regulation of complement activation
J	0032991	cellular_component	protein-containing complex
J	0033218	molecular_function	amide binding
J	0035632	cellular_component	mitochondrial prohibitin complex
J	0039529	biological_process	RIG-I signaling pathway
J	0042113	biological_process	B cell activation
J	0042802	molecular_function	identical protein binding
J	0042803	molecular_function	protein homodimerization activity
J	0043066	biological_process	negative regulation of apoptotic process
J	0043410	biological_process	positive regulation of MAPK cascade
J	0045892	biological_process	negative regulation of DNA-templated transcription
J	0046625	molecular_function	sphingolipid binding
J	0046982	molecular_function	protein heterodimerization activity
J	0050821	biological_process	protein stabilization
J	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
J	0071944	cellular_component	cell periphery
J	0098800	cellular_component	inner mitochondrial membrane protein complex
J	0140374	biological_process	antiviral innate immune response
J	1900208	biological_process	regulation of cardiolipin metabolic process
J	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
K	0000122	biological_process	negative regulation of transcription by RNA polymerase II
K	0001649	biological_process	osteoblast differentiation
K	0001850	molecular_function	complement component C3a binding
K	0001851	molecular_function	complement component C3b binding
K	0002639	biological_process	positive regulation of immunoglobulin production
K	0003714	molecular_function	transcription corepressor activity
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005737	cellular_component	cytoplasm
K	0005739	cellular_component	mitochondrion
K	0005743	cellular_component	mitochondrial inner membrane
K	0005769	cellular_component	early endosome
K	0005886	cellular_component	plasma membrane
K	0006355	biological_process	regulation of DNA-templated transcription
K	0007005	biological_process	mitochondrion organization
K	0007165	biological_process	signal transduction
K	0008285	biological_process	negative regulation of cell population proliferation
K	0009986	cellular_component	cell surface
K	0010628	biological_process	positive regulation of gene expression
K	0010944	biological_process	negative regulation of transcription by competitive promoter binding
K	0016020	cellular_component	membrane
K	0019899	molecular_function	enzyme binding
K	0030308	biological_process	negative regulation of cell growth
K	0031871	molecular_function	proteinase activated receptor binding
K	0032740	biological_process	positive regulation of interleukin-17 production
K	0035632	cellular_component	mitochondrial prohibitin complex
K	0039529	biological_process	RIG-I signaling pathway
K	0040029	biological_process	epigenetic regulation of gene expression
K	0042113	biological_process	B cell activation
K	0042177	biological_process	negative regulation of protein catabolic process
K	0042826	molecular_function	histone deacetylase binding
K	0042981	biological_process	regulation of apoptotic process
K	0043525	biological_process	positive regulation of neuron apoptotic process
K	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
K	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
K	0045892	biological_process	negative regulation of DNA-templated transcription
K	0045893	biological_process	positive regulation of DNA-templated transcription
K	0045917	biological_process	positive regulation of complement activation
K	0046718	biological_process	symbiont entry into host cell
K	0046982	molecular_function	protein heterodimerization activity
K	0048661	biological_process	positive regulation of smooth muscle cell proliferation
K	0050821	biological_process	protein stabilization
K	0050847	biological_process	progesterone receptor signaling pathway
K	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
K	0060766	biological_process	negative regulation of androgen receptor signaling pathway
K	0070062	cellular_component	extracellular exosome
K	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
K	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
K	0071354	biological_process	cellular response to interleukin-6
K	0071897	biological_process	DNA biosynthetic process
K	0072538	biological_process	T-helper 17 type immune response
K	0140374	biological_process	antiviral innate immune response
K	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
K	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
L	0000423	biological_process	mitophagy
L	0002639	biological_process	positive regulation of immunoglobulin production
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005737	cellular_component	cytoplasm
L	0005739	cellular_component	mitochondrion
L	0005741	cellular_component	mitochondrial outer membrane
L	0005743	cellular_component	mitochondrial inner membrane
L	0005886	cellular_component	plasma membrane
L	0006351	biological_process	DNA-templated transcription
L	0006357	biological_process	regulation of transcription by RNA polymerase II
L	0006606	biological_process	protein import into nucleus
L	0007005	biological_process	mitochondrion organization
L	0007062	biological_process	sister chromatid cohesion
L	0009986	cellular_component	cell surface
L	0016363	cellular_component	nuclear matrix
L	0016477	biological_process	cell migration
L	0030331	molecular_function	nuclear estrogen receptor binding
L	0030449	biological_process	regulation of complement activation
L	0032991	cellular_component	protein-containing complex
L	0033218	molecular_function	amide binding
L	0035632	cellular_component	mitochondrial prohibitin complex
L	0039529	biological_process	RIG-I signaling pathway
L	0042113	biological_process	B cell activation
L	0042802	molecular_function	identical protein binding
L	0042803	molecular_function	protein homodimerization activity
L	0043066	biological_process	negative regulation of apoptotic process
L	0043410	biological_process	positive regulation of MAPK cascade
L	0045892	biological_process	negative regulation of DNA-templated transcription
L	0046625	molecular_function	sphingolipid binding
L	0046982	molecular_function	protein heterodimerization activity
L	0050821	biological_process	protein stabilization
L	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
L	0071944	cellular_component	cell periphery
L	0098800	cellular_component	inner mitochondrial membrane protein complex
L	0140374	biological_process	antiviral innate immune response
L	1900208	biological_process	regulation of cardiolipin metabolic process
L	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
M	0000122	biological_process	negative regulation of transcription by RNA polymerase II
M	0001649	biological_process	osteoblast differentiation
M	0001850	molecular_function	complement component C3a binding
M	0001851	molecular_function	complement component C3b binding
M	0002639	biological_process	positive regulation of immunoglobulin production
M	0003714	molecular_function	transcription corepressor activity
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0005654	cellular_component	nucleoplasm
M	0005737	cellular_component	cytoplasm
M	0005739	cellular_component	mitochondrion
M	0005743	cellular_component	mitochondrial inner membrane
M	0005769	cellular_component	early endosome
M	0005886	cellular_component	plasma membrane
M	0006355	biological_process	regulation of DNA-templated transcription
M	0007005	biological_process	mitochondrion organization
M	0007165	biological_process	signal transduction
M	0008285	biological_process	negative regulation of cell population proliferation
M	0009986	cellular_component	cell surface
M	0010628	biological_process	positive regulation of gene expression
M	0010944	biological_process	negative regulation of transcription by competitive promoter binding
M	0016020	cellular_component	membrane
M	0019899	molecular_function	enzyme binding
M	0030308	biological_process	negative regulation of cell growth
M	0031871	molecular_function	proteinase activated receptor binding
M	0032740	biological_process	positive regulation of interleukin-17 production
M	0035632	cellular_component	mitochondrial prohibitin complex
M	0039529	biological_process	RIG-I signaling pathway
M	0040029	biological_process	epigenetic regulation of gene expression
M	0042113	biological_process	B cell activation
M	0042177	biological_process	negative regulation of protein catabolic process
M	0042826	molecular_function	histone deacetylase binding
M	0042981	biological_process	regulation of apoptotic process
M	0043525	biological_process	positive regulation of neuron apoptotic process
M	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
M	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
M	0045892	biological_process	negative regulation of DNA-templated transcription
M	0045893	biological_process	positive regulation of DNA-templated transcription
M	0045917	biological_process	positive regulation of complement activation
M	0046718	biological_process	symbiont entry into host cell
M	0046982	molecular_function	protein heterodimerization activity
M	0048661	biological_process	positive regulation of smooth muscle cell proliferation
M	0050821	biological_process	protein stabilization
M	0050847	biological_process	progesterone receptor signaling pathway
M	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
M	0060766	biological_process	negative regulation of androgen receptor signaling pathway
M	0070062	cellular_component	extracellular exosome
M	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
M	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
M	0071354	biological_process	cellular response to interleukin-6
M	0071897	biological_process	DNA biosynthetic process
M	0072538	biological_process	T-helper 17 type immune response
M	0140374	biological_process	antiviral innate immune response
M	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
M	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
N	0000423	biological_process	mitophagy
N	0002639	biological_process	positive regulation of immunoglobulin production
N	0005515	molecular_function	protein binding
N	0005634	cellular_component	nucleus
N	0005737	cellular_component	cytoplasm
N	0005739	cellular_component	mitochondrion
N	0005741	cellular_component	mitochondrial outer membrane
N	0005743	cellular_component	mitochondrial inner membrane
N	0005886	cellular_component	plasma membrane
N	0006351	biological_process	DNA-templated transcription
N	0006357	biological_process	regulation of transcription by RNA polymerase II
N	0006606	biological_process	protein import into nucleus
N	0007005	biological_process	mitochondrion organization
N	0007062	biological_process	sister chromatid cohesion
N	0009986	cellular_component	cell surface
N	0016363	cellular_component	nuclear matrix
N	0016477	biological_process	cell migration
N	0030331	molecular_function	nuclear estrogen receptor binding
N	0030449	biological_process	regulation of complement activation
N	0032991	cellular_component	protein-containing complex
N	0033218	molecular_function	amide binding
N	0035632	cellular_component	mitochondrial prohibitin complex
N	0039529	biological_process	RIG-I signaling pathway
N	0042113	biological_process	B cell activation
N	0042802	molecular_function	identical protein binding
N	0042803	molecular_function	protein homodimerization activity
N	0043066	biological_process	negative regulation of apoptotic process
N	0043410	biological_process	positive regulation of MAPK cascade
N	0045892	biological_process	negative regulation of DNA-templated transcription
N	0046625	molecular_function	sphingolipid binding
N	0046982	molecular_function	protein heterodimerization activity
N	0050821	biological_process	protein stabilization
N	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
N	0071944	cellular_component	cell periphery
N	0098800	cellular_component	inner mitochondrial membrane protein complex
N	0140374	biological_process	antiviral innate immune response
N	1900208	biological_process	regulation of cardiolipin metabolic process
N	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
O	0000122	biological_process	negative regulation of transcription by RNA polymerase II
O	0001649	biological_process	osteoblast differentiation
O	0001850	molecular_function	complement component C3a binding
O	0001851	molecular_function	complement component C3b binding
O	0002639	biological_process	positive regulation of immunoglobulin production
O	0003714	molecular_function	transcription corepressor activity
O	0005515	molecular_function	protein binding
O	0005634	cellular_component	nucleus
O	0005654	cellular_component	nucleoplasm
O	0005737	cellular_component	cytoplasm
O	0005739	cellular_component	mitochondrion
O	0005743	cellular_component	mitochondrial inner membrane
O	0005769	cellular_component	early endosome
O	0005886	cellular_component	plasma membrane
O	0006355	biological_process	regulation of DNA-templated transcription
O	0007005	biological_process	mitochondrion organization
O	0007165	biological_process	signal transduction
O	0008285	biological_process	negative regulation of cell population proliferation
O	0009986	cellular_component	cell surface
O	0010628	biological_process	positive regulation of gene expression
O	0010944	biological_process	negative regulation of transcription by competitive promoter binding
O	0016020	cellular_component	membrane
O	0019899	molecular_function	enzyme binding
O	0030308	biological_process	negative regulation of cell growth
O	0031871	molecular_function	proteinase activated receptor binding
O	0032740	biological_process	positive regulation of interleukin-17 production
O	0035632	cellular_component	mitochondrial prohibitin complex
O	0039529	biological_process	RIG-I signaling pathway
O	0040029	biological_process	epigenetic regulation of gene expression
O	0042113	biological_process	B cell activation
O	0042177	biological_process	negative regulation of protein catabolic process
O	0042826	molecular_function	histone deacetylase binding
O	0042981	biological_process	regulation of apoptotic process
O	0043525	biological_process	positive regulation of neuron apoptotic process
O	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
O	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
O	0045892	biological_process	negative regulation of DNA-templated transcription
O	0045893	biological_process	positive regulation of DNA-templated transcription
O	0045917	biological_process	positive regulation of complement activation
O	0046718	biological_process	symbiont entry into host cell
O	0046982	molecular_function	protein heterodimerization activity
O	0048661	biological_process	positive regulation of smooth muscle cell proliferation
O	0050821	biological_process	protein stabilization
O	0050847	biological_process	progesterone receptor signaling pathway
O	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
O	0060766	biological_process	negative regulation of androgen receptor signaling pathway
O	0070062	cellular_component	extracellular exosome
O	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
O	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
O	0071354	biological_process	cellular response to interleukin-6
O	0071897	biological_process	DNA biosynthetic process
O	0072538	biological_process	T-helper 17 type immune response
O	0140374	biological_process	antiviral innate immune response
O	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
O	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
P	0000423	biological_process	mitophagy
P	0002639	biological_process	positive regulation of immunoglobulin production
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005737	cellular_component	cytoplasm
P	0005739	cellular_component	mitochondrion
P	0005741	cellular_component	mitochondrial outer membrane
P	0005743	cellular_component	mitochondrial inner membrane
P	0005886	cellular_component	plasma membrane
P	0006351	biological_process	DNA-templated transcription
P	0006357	biological_process	regulation of transcription by RNA polymerase II
P	0006606	biological_process	protein import into nucleus
P	0007005	biological_process	mitochondrion organization
P	0007062	biological_process	sister chromatid cohesion
P	0009986	cellular_component	cell surface
P	0016363	cellular_component	nuclear matrix
P	0016477	biological_process	cell migration
P	0030331	molecular_function	nuclear estrogen receptor binding
P	0030449	biological_process	regulation of complement activation
P	0032991	cellular_component	protein-containing complex
P	0033218	molecular_function	amide binding
P	0035632	cellular_component	mitochondrial prohibitin complex
P	0039529	biological_process	RIG-I signaling pathway
P	0042113	biological_process	B cell activation
P	0042802	molecular_function	identical protein binding
P	0042803	molecular_function	protein homodimerization activity
P	0043066	biological_process	negative regulation of apoptotic process
P	0043410	biological_process	positive regulation of MAPK cascade
P	0045892	biological_process	negative regulation of DNA-templated transcription
P	0046625	molecular_function	sphingolipid binding
P	0046982	molecular_function	protein heterodimerization activity
P	0050821	biological_process	protein stabilization
P	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
P	0071944	cellular_component	cell periphery
P	0098800	cellular_component	inner mitochondrial membrane protein complex
P	0140374	biological_process	antiviral innate immune response
P	1900208	biological_process	regulation of cardiolipin metabolic process
P	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
Q	0000122	biological_process	negative regulation of transcription by RNA polymerase II
Q	0001649	biological_process	osteoblast differentiation
Q	0001850	molecular_function	complement component C3a binding
Q	0001851	molecular_function	complement component C3b binding
Q	0002639	biological_process	positive regulation of immunoglobulin production
Q	0003714	molecular_function	transcription corepressor activity
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005654	cellular_component	nucleoplasm
Q	0005737	cellular_component	cytoplasm
Q	0005739	cellular_component	mitochondrion
Q	0005743	cellular_component	mitochondrial inner membrane
Q	0005769	cellular_component	early endosome
Q	0005886	cellular_component	plasma membrane
Q	0006355	biological_process	regulation of DNA-templated transcription
Q	0007005	biological_process	mitochondrion organization
Q	0007165	biological_process	signal transduction
Q	0008285	biological_process	negative regulation of cell population proliferation
Q	0009986	cellular_component	cell surface
Q	0010628	biological_process	positive regulation of gene expression
Q	0010944	biological_process	negative regulation of transcription by competitive promoter binding
Q	0016020	cellular_component	membrane
Q	0019899	molecular_function	enzyme binding
Q	0030308	biological_process	negative regulation of cell growth
Q	0031871	molecular_function	proteinase activated receptor binding
Q	0032740	biological_process	positive regulation of interleukin-17 production
Q	0035632	cellular_component	mitochondrial prohibitin complex
Q	0039529	biological_process	RIG-I signaling pathway
Q	0040029	biological_process	epigenetic regulation of gene expression
Q	0042113	biological_process	B cell activation
Q	0042177	biological_process	negative regulation of protein catabolic process
Q	0042826	molecular_function	histone deacetylase binding
Q	0042981	biological_process	regulation of apoptotic process
Q	0043525	biological_process	positive regulation of neuron apoptotic process
Q	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
Q	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
Q	0045892	biological_process	negative regulation of DNA-templated transcription
Q	0045893	biological_process	positive regulation of DNA-templated transcription
Q	0045917	biological_process	positive regulation of complement activation
Q	0046718	biological_process	symbiont entry into host cell
Q	0046982	molecular_function	protein heterodimerization activity
Q	0048661	biological_process	positive regulation of smooth muscle cell proliferation
Q	0050821	biological_process	protein stabilization
Q	0050847	biological_process	progesterone receptor signaling pathway
Q	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
Q	0060766	biological_process	negative regulation of androgen receptor signaling pathway
Q	0070062	cellular_component	extracellular exosome
Q	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
Q	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
Q	0071354	biological_process	cellular response to interleukin-6
Q	0071897	biological_process	DNA biosynthetic process
Q	0072538	biological_process	T-helper 17 type immune response
Q	0140374	biological_process	antiviral innate immune response
Q	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
Q	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
R	0000423	biological_process	mitophagy
R	0002639	biological_process	positive regulation of immunoglobulin production
R	0005515	molecular_function	protein binding
R	0005634	cellular_component	nucleus
R	0005737	cellular_component	cytoplasm
R	0005739	cellular_component	mitochondrion
R	0005741	cellular_component	mitochondrial outer membrane
R	0005743	cellular_component	mitochondrial inner membrane
R	0005886	cellular_component	plasma membrane
R	0006351	biological_process	DNA-templated transcription
R	0006357	biological_process	regulation of transcription by RNA polymerase II
R	0006606	biological_process	protein import into nucleus
R	0007005	biological_process	mitochondrion organization
R	0007062	biological_process	sister chromatid cohesion
R	0009986	cellular_component	cell surface
R	0016363	cellular_component	nuclear matrix
R	0016477	biological_process	cell migration
R	0030331	molecular_function	nuclear estrogen receptor binding
R	0030449	biological_process	regulation of complement activation
R	0032991	cellular_component	protein-containing complex
R	0033218	molecular_function	amide binding
R	0035632	cellular_component	mitochondrial prohibitin complex
R	0039529	biological_process	RIG-I signaling pathway
R	0042113	biological_process	B cell activation
R	0042802	molecular_function	identical protein binding
R	0042803	molecular_function	protein homodimerization activity
R	0043066	biological_process	negative regulation of apoptotic process
R	0043410	biological_process	positive regulation of MAPK cascade
R	0045892	biological_process	negative regulation of DNA-templated transcription
R	0046625	molecular_function	sphingolipid binding
R	0046982	molecular_function	protein heterodimerization activity
R	0050821	biological_process	protein stabilization
R	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
R	0071944	cellular_component	cell periphery
R	0098800	cellular_component	inner mitochondrial membrane protein complex
R	0140374	biological_process	antiviral innate immune response
R	1900208	biological_process	regulation of cardiolipin metabolic process
R	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
S	0000122	biological_process	negative regulation of transcription by RNA polymerase II
S	0001649	biological_process	osteoblast differentiation
S	0001850	molecular_function	complement component C3a binding
S	0001851	molecular_function	complement component C3b binding
S	0002639	biological_process	positive regulation of immunoglobulin production
S	0003714	molecular_function	transcription corepressor activity
S	0005515	molecular_function	protein binding
S	0005634	cellular_component	nucleus
S	0005654	cellular_component	nucleoplasm
S	0005737	cellular_component	cytoplasm
S	0005739	cellular_component	mitochondrion
S	0005743	cellular_component	mitochondrial inner membrane
S	0005769	cellular_component	early endosome
S	0005886	cellular_component	plasma membrane
S	0006355	biological_process	regulation of DNA-templated transcription
S	0007005	biological_process	mitochondrion organization
S	0007165	biological_process	signal transduction
S	0008285	biological_process	negative regulation of cell population proliferation
S	0009986	cellular_component	cell surface
S	0010628	biological_process	positive regulation of gene expression
S	0010944	biological_process	negative regulation of transcription by competitive promoter binding
S	0016020	cellular_component	membrane
S	0019899	molecular_function	enzyme binding
S	0030308	biological_process	negative regulation of cell growth
S	0031871	molecular_function	proteinase activated receptor binding
S	0032740	biological_process	positive regulation of interleukin-17 production
S	0035632	cellular_component	mitochondrial prohibitin complex
S	0039529	biological_process	RIG-I signaling pathway
S	0040029	biological_process	epigenetic regulation of gene expression
S	0042113	biological_process	B cell activation
S	0042177	biological_process	negative regulation of protein catabolic process
S	0042826	molecular_function	histone deacetylase binding
S	0042981	biological_process	regulation of apoptotic process
S	0043525	biological_process	positive regulation of neuron apoptotic process
S	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
S	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
S	0045892	biological_process	negative regulation of DNA-templated transcription
S	0045893	biological_process	positive regulation of DNA-templated transcription
S	0045917	biological_process	positive regulation of complement activation
S	0046718	biological_process	symbiont entry into host cell
S	0046982	molecular_function	protein heterodimerization activity
S	0048661	biological_process	positive regulation of smooth muscle cell proliferation
S	0050821	biological_process	protein stabilization
S	0050847	biological_process	progesterone receptor signaling pathway
S	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
S	0060766	biological_process	negative regulation of androgen receptor signaling pathway
S	0070062	cellular_component	extracellular exosome
S	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
S	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
S	0071354	biological_process	cellular response to interleukin-6
S	0071897	biological_process	DNA biosynthetic process
S	0072538	biological_process	T-helper 17 type immune response
S	0140374	biological_process	antiviral innate immune response
S	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
S	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
T	0000423	biological_process	mitophagy
T	0002639	biological_process	positive regulation of immunoglobulin production
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005737	cellular_component	cytoplasm
T	0005739	cellular_component	mitochondrion
T	0005741	cellular_component	mitochondrial outer membrane
T	0005743	cellular_component	mitochondrial inner membrane
T	0005886	cellular_component	plasma membrane
T	0006351	biological_process	DNA-templated transcription
T	0006357	biological_process	regulation of transcription by RNA polymerase II
T	0006606	biological_process	protein import into nucleus
T	0007005	biological_process	mitochondrion organization
T	0007062	biological_process	sister chromatid cohesion
T	0009986	cellular_component	cell surface
T	0016363	cellular_component	nuclear matrix
T	0016477	biological_process	cell migration
T	0030331	molecular_function	nuclear estrogen receptor binding
T	0030449	biological_process	regulation of complement activation
T	0032991	cellular_component	protein-containing complex
T	0033218	molecular_function	amide binding
T	0035632	cellular_component	mitochondrial prohibitin complex
T	0039529	biological_process	RIG-I signaling pathway
T	0042113	biological_process	B cell activation
T	0042802	molecular_function	identical protein binding
T	0042803	molecular_function	protein homodimerization activity
T	0043066	biological_process	negative regulation of apoptotic process
T	0043410	biological_process	positive regulation of MAPK cascade
T	0045892	biological_process	negative regulation of DNA-templated transcription
T	0046625	molecular_function	sphingolipid binding
T	0046982	molecular_function	protein heterodimerization activity
T	0050821	biological_process	protein stabilization
T	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
T	0071944	cellular_component	cell periphery
T	0098800	cellular_component	inner mitochondrial membrane protein complex
T	0140374	biological_process	antiviral innate immune response
T	1900208	biological_process	regulation of cardiolipin metabolic process
T	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
U	0000122	biological_process	negative regulation of transcription by RNA polymerase II
U	0001649	biological_process	osteoblast differentiation
U	0001850	molecular_function	complement component C3a binding
U	0001851	molecular_function	complement component C3b binding
U	0002639	biological_process	positive regulation of immunoglobulin production
U	0003714	molecular_function	transcription corepressor activity
U	0005515	molecular_function	protein binding
U	0005634	cellular_component	nucleus
U	0005654	cellular_component	nucleoplasm
U	0005737	cellular_component	cytoplasm
U	0005739	cellular_component	mitochondrion
U	0005743	cellular_component	mitochondrial inner membrane
U	0005769	cellular_component	early endosome
U	0005886	cellular_component	plasma membrane
U	0006355	biological_process	regulation of DNA-templated transcription
U	0007005	biological_process	mitochondrion organization
U	0007165	biological_process	signal transduction
U	0008285	biological_process	negative regulation of cell population proliferation
U	0009986	cellular_component	cell surface
U	0010628	biological_process	positive regulation of gene expression
U	0010944	biological_process	negative regulation of transcription by competitive promoter binding
U	0016020	cellular_component	membrane
U	0019899	molecular_function	enzyme binding
U	0030308	biological_process	negative regulation of cell growth
U	0031871	molecular_function	proteinase activated receptor binding
U	0032740	biological_process	positive regulation of interleukin-17 production
U	0035632	cellular_component	mitochondrial prohibitin complex
U	0039529	biological_process	RIG-I signaling pathway
U	0040029	biological_process	epigenetic regulation of gene expression
U	0042113	biological_process	B cell activation
U	0042177	biological_process	negative regulation of protein catabolic process
U	0042826	molecular_function	histone deacetylase binding
U	0042981	biological_process	regulation of apoptotic process
U	0043525	biological_process	positive regulation of neuron apoptotic process
U	0044830	biological_process	host-mediated perturbation of viral RNA genome replication
U	0045745	biological_process	positive regulation of G protein-coupled receptor signaling pathway
U	0045892	biological_process	negative regulation of DNA-templated transcription
U	0045893	biological_process	positive regulation of DNA-templated transcription
U	0045917	biological_process	positive regulation of complement activation
U	0046718	biological_process	symbiont entry into host cell
U	0046982	molecular_function	protein heterodimerization activity
U	0048661	biological_process	positive regulation of smooth muscle cell proliferation
U	0050821	biological_process	protein stabilization
U	0050847	biological_process	progesterone receptor signaling pathway
U	0051897	biological_process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
U	0060766	biological_process	negative regulation of androgen receptor signaling pathway
U	0070062	cellular_component	extracellular exosome
U	0070373	biological_process	negative regulation of ERK1 and ERK2 cascade
U	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
U	0071354	biological_process	cellular response to interleukin-6
U	0071897	biological_process	DNA biosynthetic process
U	0072538	biological_process	T-helper 17 type immune response
U	0140374	biological_process	antiviral innate immune response
U	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
U	2000323	biological_process	negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
V	0000423	biological_process	mitophagy
V	0002639	biological_process	positive regulation of immunoglobulin production
V	0005515	molecular_function	protein binding
V	0005634	cellular_component	nucleus
V	0005737	cellular_component	cytoplasm
V	0005739	cellular_component	mitochondrion
V	0005741	cellular_component	mitochondrial outer membrane
V	0005743	cellular_component	mitochondrial inner membrane
V	0005886	cellular_component	plasma membrane
V	0006351	biological_process	DNA-templated transcription
V	0006357	biological_process	regulation of transcription by RNA polymerase II
V	0006606	biological_process	protein import into nucleus
V	0007005	biological_process	mitochondrion organization
V	0007062	biological_process	sister chromatid cohesion
V	0009986	cellular_component	cell surface
V	0016363	cellular_component	nuclear matrix
V	0016477	biological_process	cell migration
V	0030331	molecular_function	nuclear estrogen receptor binding
V	0030449	biological_process	regulation of complement activation
V	0032991	cellular_component	protein-containing complex
V	0033218	molecular_function	amide binding
V	0035632	cellular_component	mitochondrial prohibitin complex
V	0039529	biological_process	RIG-I signaling pathway
V	0042113	biological_process	B cell activation
V	0042802	molecular_function	identical protein binding
V	0042803	molecular_function	protein homodimerization activity
V	0043066	biological_process	negative regulation of apoptotic process
V	0043410	biological_process	positive regulation of MAPK cascade
V	0045892	biological_process	negative regulation of DNA-templated transcription
V	0046625	molecular_function	sphingolipid binding
V	0046982	molecular_function	protein heterodimerization activity
V	0050821	biological_process	protein stabilization
V	0070374	biological_process	positive regulation of ERK1 and ERK2 cascade
V	0071944	cellular_component	cell periphery
V	0098800	cellular_component	inner mitochondrial membrane protein complex
V	0140374	biological_process	antiviral innate immune response
V	1900208	biological_process	regulation of cardiolipin metabolic process
V	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	170
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	5
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	13
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P67778","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	11
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P67778","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	11
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	15
Details	Region: {"description":"LC3-interaction region","evidences":[{"source":"PubMed","id":"28017329","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	120
Details	Region: {"description":"Necessary for transcriptional repression","evidences":[{"source":"PubMed","id":"10359819","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	240
Details	Coiled coil: {"evidences":[{"source":"PubMed","id":"28017329","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6IQE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	5
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	38
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"O35129","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	5
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	11
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---