9UMT

TRiC_HDAC1_close_state

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002199	cellular_component	zona pellucida receptor complex
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005832	cellular_component	chaperonin-containing T-complex
A	0005874	cellular_component	microtubule
A	0006457	biological_process	protein folding
A	0031625	molecular_function	ubiquitin protein ligase binding
A	0032212	biological_process	positive regulation of telomere maintenance via telomerase
A	0035578	cellular_component	azurophil granule lumen
A	0044183	molecular_function	protein folding chaperone
A	0044297	cellular_component	cell body
A	0050821	biological_process	protein stabilization
A	0051082	molecular_function	obsolete unfolded protein binding
A	0051131	biological_process	chaperone-mediated protein complex assembly
A	0070062	cellular_component	extracellular exosome
A	0090666	biological_process	scaRNA localization to Cajal body
A	1904871	biological_process	positive regulation of protein localization to Cajal body
A	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
B	0002199	cellular_component	zona pellucida receptor complex
B	0003723	molecular_function	RNA binding
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005813	cellular_component	centrosome
B	0005829	cellular_component	cytosol
B	0005832	cellular_component	chaperonin-containing T-complex
B	0005874	cellular_component	microtubule
B	0006457	biological_process	protein folding
B	0016887	molecular_function	ATP hydrolysis activity
B	0032212	biological_process	positive regulation of telomere maintenance via telomerase
B	0042470	cellular_component	melanosome
B	0044183	molecular_function	protein folding chaperone
B	0044297	cellular_component	cell body
B	0050821	biological_process	protein stabilization
B	0051082	molecular_function	obsolete unfolded protein binding
B	0070062	cellular_component	extracellular exosome
B	0090666	biological_process	scaRNA localization to Cajal body
B	1904871	biological_process	positive regulation of protein localization to Cajal body
B	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
C	0002199	cellular_component	zona pellucida receptor complex
C	0003723	molecular_function	RNA binding
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005832	cellular_component	chaperonin-containing T-complex
C	0005856	cellular_component	cytoskeleton
C	0005874	cellular_component	microtubule
C	0006457	biological_process	protein folding
C	0032212	biological_process	positive regulation of telomere maintenance via telomerase
C	0044183	molecular_function	protein folding chaperone
C	0044297	cellular_component	cell body
C	0050821	biological_process	protein stabilization
C	0051082	molecular_function	obsolete unfolded protein binding
C	0070062	cellular_component	extracellular exosome
C	1904871	biological_process	positive regulation of protein localization to Cajal body
C	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
D	0005737	cellular_component	cytoplasm
D	0005832	cellular_component	chaperonin-containing T-complex
D	0032212	biological_process	positive regulation of telomere maintenance via telomerase
D	0044183	molecular_function	protein folding chaperone
D	0050821	biological_process	protein stabilization
E	0002199	cellular_component	zona pellucida receptor complex
E	0005515	molecular_function	protein binding
E	0005576	cellular_component	extracellular region
E	0005737	cellular_component	cytoplasm
E	0005813	cellular_component	centrosome
E	0005829	cellular_component	cytosol
E	0005832	cellular_component	chaperonin-containing T-complex
E	0005874	cellular_component	microtubule
E	0006457	biological_process	protein folding
E	0032212	biological_process	positive regulation of telomere maintenance via telomerase
E	0034774	cellular_component	secretory granule lumen
E	0035578	cellular_component	azurophil granule lumen
E	0044183	molecular_function	protein folding chaperone
E	0044297	cellular_component	cell body
E	0045296	molecular_function	cadherin binding
E	0050821	biological_process	protein stabilization
E	0070062	cellular_component	extracellular exosome
E	1904813	cellular_component	ficolin-1-rich granule lumen
E	1904871	biological_process	positive regulation of protein localization to Cajal body
E	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
F	0000242	cellular_component	pericentriolar material
F	0000792	cellular_component	heterochromatin
F	0001669	cellular_component	acrosomal vesicle
F	0002199	cellular_component	zona pellucida receptor complex
F	0003723	molecular_function	RNA binding
F	0005515	molecular_function	protein binding
F	0005794	cellular_component	Golgi apparatus
F	0005813	cellular_component	centrosome
F	0005815	cellular_component	microtubule organizing center
F	0005829	cellular_component	cytosol
F	0005832	cellular_component	chaperonin-containing T-complex
F	0005874	cellular_component	microtubule
F	0006457	biological_process	protein folding
F	0007021	biological_process	tubulin complex assembly
F	0031625	molecular_function	ubiquitin protein ligase binding
F	0032212	biological_process	positive regulation of telomere maintenance via telomerase
F	0044183	molecular_function	protein folding chaperone
F	0044297	cellular_component	cell body
F	0050821	biological_process	protein stabilization
F	0051082	molecular_function	obsolete unfolded protein binding
F	0070062	cellular_component	extracellular exosome
F	0090666	biological_process	scaRNA localization to Cajal body
F	1904851	biological_process	positive regulation of establishment of protein localization to telomere
F	1904871	biological_process	positive regulation of protein localization to Cajal body
F	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
G	0003730	molecular_function	mRNA 3'-UTR binding
G	0005515	molecular_function	protein binding
G	0005737	cellular_component	cytoplasm
G	0005813	cellular_component	centrosome
G	0005829	cellular_component	cytosol
G	0005832	cellular_component	chaperonin-containing T-complex
G	0005874	cellular_component	microtubule
G	0006457	biological_process	protein folding
G	0009615	biological_process	response to virus
G	0016887	molecular_function	ATP hydrolysis activity
G	0031681	molecular_function	G-protein beta-subunit binding
G	0032212	biological_process	positive regulation of telomere maintenance via telomerase
G	0044183	molecular_function	protein folding chaperone
G	0044297	cellular_component	cell body
G	0048027	molecular_function	mRNA 5'-UTR binding
G	0048487	molecular_function	beta-tubulin binding
G	0050821	biological_process	protein stabilization
G	0070062	cellular_component	extracellular exosome
G	1904871	biological_process	positive regulation of protein localization to Cajal body
G	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
H	0003723	molecular_function	RNA binding
H	0005515	molecular_function	protein binding
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0005832	cellular_component	chaperonin-containing T-complex
H	0005874	cellular_component	microtubule
H	0006457	biological_process	protein folding
H	0032212	biological_process	positive regulation of telomere maintenance via telomerase
H	0044183	molecular_function	protein folding chaperone
H	0050821	biological_process	protein stabilization
H	0051082	molecular_function	obsolete unfolded protein binding
H	0070062	cellular_component	extracellular exosome
H	0071987	molecular_function	WD40-repeat domain binding
H	1904851	biological_process	positive regulation of establishment of protein localization to telomere
H	1904871	biological_process	positive regulation of protein localization to Cajal body
H	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body

Functional Information from PROSITE/UniProt

site_id	PS00107
Number of Residues	26
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. VGDGTTSVTVlAaellreaesl........IAKK

Chain	Residue	Details
A	VAL95-LYS120

---

site_id	PS00141
Number of Residues	12
Details	ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. AIADTGANVVVT

Chain	Residue	Details
E	ALA282-THR293

---

site_id	PS00750
Number of Residues	13
Details	TCP1_1 Chaperonins TCP-1 signature 1. RTsLGPnGldKMM

Chain	Residue	Details
G	ARG47-MET59
D	ARG37-ILE49
F	LYS33-LEU45
B	ARG49-ILE61
C	ARG38-LEU50
H	ARG35-LEU47
A	LYS40-LEU52
E	ARG44-VAL56

---

site_id	PS00751
Number of Residues	17
Details	TCP1_2 Chaperonins TCP-1 signature 2. VTNDGATILsmMdVdHQ

Chain	Residue	Details
G	VAL68-GLN84
D	ILE58-PRO74
F	ILE54-PRO70
B	ILE70-PRO86
C	MET59-PRO75
H	LEU56-PRO72
A	VAL63-PRO79
E	VAL65-PRO81

---

site_id	PS00995
Number of Residues	9
Details	TCP1_3 Chaperonins TCP-1 signature 3. QDdeIGDGT

Chain	Residue	Details
G	GLN96-THR104
D	GLN86-THR94
F	GLN82-THR90
B	GLN98-THR106
C	GLN87-THR95
H	GLN84-THR92
A	GLN91-THR99
E	GLN93-THR101

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	41
Details	Binding site: {"evidences":[{"source":"PubMed","id":"37193829","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7X3J","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35449234","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36493755","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37193829","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TRG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TUB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0V","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35449234","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36493755","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TUB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35449234","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36493755","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TRG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TUB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35449234","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NVL","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35449234","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36493755","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37193829","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TRG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TUB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0V","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35449234","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36493755","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37193829","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TRG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0V","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	15
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	17
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P11983","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35449234","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36493755","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37193829","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TUB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0V","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35449234","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36493755","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37193829","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NVN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TRG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TUB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0V","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35449234","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36493755","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TRG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTT","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAY-2004","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Potts A.","Quadroni M."]}},{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	18
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35449234","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36493755","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TRG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TUB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35449234","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36493755","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37193829","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TRG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TUB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0V","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35449234","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35449234","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36493755","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37193829","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TRG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TUB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7WZ3","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35449234","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NVN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P80318","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25114211","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35449234","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36493755","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37193829","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TRG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TUB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X3U","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35449234","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36493755","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TRG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TUB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35449234","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36493755","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37193829","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TRG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0V","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35449234","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36493755","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TRG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TUB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI35
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35449234","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36493755","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37193829","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TRG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TUB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X3U","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI36
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"36493755","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7TRG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI37
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35449234","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36493755","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37193829","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TRG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TUB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0V","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI38
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"37193829","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7X0S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0V","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI39
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35449234","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36493755","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37193829","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TRG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X3U","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI40
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"36493755","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7TTN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI41
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35449234","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVN","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI42
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI43
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P80317","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI44
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35449234","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36493755","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37193829","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TRG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TUB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X3U","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI45
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35449234","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36493755","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37193829","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NVL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7NVO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TTT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TUB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X3U","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI46
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"35449234","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36493755","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37193829","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7NVO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TUB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X0V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7X3U","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI47
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"OCT-2004","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V."]}}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI48
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI49
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI50
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI51
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)","evidences":[{"source":"PubMed","id":"25114211","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---