9UGC
Cryo-EM structure of the Pma1 with ordered N-terminal extension in the autoinhibited state
Functional Information from PROSITE/UniProt
| site_id | PS00154 |
| Number of Residues | 7 |
| Details | ATPASE_E1_E2 E1-E2 ATPases phosphorylation site. DKTGTLT |
| Chain | Residue | Details |
| A | ASP378-THR384 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1414 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | MET1-LYS115 | |
| B | GLU875-THR918 | |
| A | GLN161-ASN291 | |
| A | VAL348-ILE719 | |
| A | THR775-GLN824 | |
| A | GLU875-THR918 | |
| B | MET1-LYS115 | |
| B | GLN161-ASN291 | |
| B | VAL348-ILE719 | |
| B | THR775-GLN824 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 40 |
| Details | TRANSMEM: Helical; Name=1 => ECO:0000255 |
| Chain | Residue | Details |
| A | PHE116-ALA136 | |
| B | PHE116-ALA136 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 80 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| A | GLY137-ASP140 | |
| A | TYR314-TYR325 | |
| A | ASP739-ARG754 | |
| A | SER846-ARG857 | |
| B | GLY137-ASP140 | |
| B | TYR314-TYR325 | |
| B | ASP739-ARG754 | |
| B | SER846-ARG857 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 38 |
| Details | TRANSMEM: Helical; Name=2 => ECO:0000255 |
| Chain | Residue | Details |
| A | TRP141-VAL160 | |
| B | TRP141-VAL160 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 42 |
| Details | TRANSMEM: Helical; Name=3 => ECO:0000255 |
| Chain | Residue | Details |
| A | GLY292-PHE313 | |
| B | GLY292-PHE313 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 42 |
| Details | TRANSMEM: Helical; Name=4 => ECO:0000255 |
| Chain | Residue | Details |
| A | THR326-ALA347 | |
| B | THR326-ALA347 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 36 |
| Details | TRANSMEM: Helical; Name=5 => ECO:0000255 |
| Chain | Residue | Details |
| A | ASP720-TYR738 | |
| B | ASP720-TYR738 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 38 |
| Details | TRANSMEM: Helical; Name=6 => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU755-LEU774 | |
| B | LEU755-LEU774 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 40 |
| Details | TRANSMEM: Helical; Name=7 => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU825-TRP845 | |
| B | LEU825-TRP845 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 32 |
| Details | TRANSMEM: Helical; Name=8 => ECO:0000255 |
| Chain | Residue | Details |
| A | VAL858-TYR874 | |
| B | VAL858-TYR874 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 2 |
| Details | ACT_SITE: 4-aspartylphosphate intermediate => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP378 | |
| B | ASP378 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP634 | |
| A | ASP638 | |
| B | ASP634 | |
| B | ASP638 |
| site_id | SWS_FT_FI13 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956 |
| Chain | Residue | Details |
| A | SER61 | |
| B | SER61 |
| site_id | SWS_FT_FI14 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:19779198 |
| Chain | Residue | Details |
| A | THR175 | |
| B | THR175 |
| site_id | SWS_FT_FI15 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:19779198 |
| Chain | Residue | Details |
| A | SER911 | |
| B | SER911 |
| site_id | SWS_FT_FI16 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:19779198 |
| Chain | Residue | Details |
| A | THR912 | |
| B | THR912 |
| site_id | SWS_FT_FI17 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:17330950 |
| Chain | Residue | Details |
| A | THR918 | |
| B | THR918 |
| site_id | SWS_FT_FI18 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047 |
| Chain | Residue | Details |
| A | LYS252 | |
| B | LYS252 |
| site_id | SWS_FT_FI19 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:14557538 |
| Chain | Residue | Details |
| A | LYS555 | |
| B | LYS555 |
