9UCH

Crystal Structure of adenine-sulfotransferase from Bos Taurus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005829	cellular_component	cytosol
A	0006163	biological_process	purine nucleotide metabolic process
A	0015964	biological_process	diadenosine triphosphate catabolic process
A	0031625	molecular_function	ubiquitin protein ligase binding
A	0032435	biological_process	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
A	0043530	molecular_function	adenosine 5'-monophosphoramidase activity
A	0047352	molecular_function	adenylylsulfate-ammonia adenylyltransferase activity
A	0047627	molecular_function	adenylylsulfatase activity
A	0047710	molecular_function	bis(5'-adenosyl)-triphosphatase activity
A	0072332	biological_process	intrinsic apoptotic signaling pathway by p53 class mediator
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005829	cellular_component	cytosol
B	0006163	biological_process	purine nucleotide metabolic process
B	0015964	biological_process	diadenosine triphosphate catabolic process
B	0031625	molecular_function	ubiquitin protein ligase binding
B	0032435	biological_process	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
B	0043530	molecular_function	adenosine 5'-monophosphoramidase activity
B	0047352	molecular_function	adenylylsulfate-ammonia adenylyltransferase activity
B	0047627	molecular_function	adenylylsulfatase activity
B	0047710	molecular_function	bis(5'-adenosyl)-triphosphatase activity
B	0072332	biological_process	intrinsic apoptotic signaling pathway by p53 class mediator
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005829	cellular_component	cytosol
C	0006163	biological_process	purine nucleotide metabolic process
C	0015964	biological_process	diadenosine triphosphate catabolic process
C	0031625	molecular_function	ubiquitin protein ligase binding
C	0032435	biological_process	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
C	0043530	molecular_function	adenosine 5'-monophosphoramidase activity
C	0047352	molecular_function	adenylylsulfate-ammonia adenylyltransferase activity
C	0047627	molecular_function	adenylylsulfatase activity
C	0047710	molecular_function	bis(5'-adenosyl)-triphosphatase activity
C	0072332	biological_process	intrinsic apoptotic signaling pathway by p53 class mediator

Functional Information from PROSITE/UniProt

site_id	PS00892
Number of Residues	19
Details	HIT_1 HIT domain signature. QdgpeAgQtVkHVHVHILP

Chain	Residue	Details
A	GLN83-PRO101

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Motif: {"description":"Histidine triad motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU00464","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	Active site: {"description":"Tele-AMP-histidine intermediate","evidences":[{"source":"UniProtKB","id":"P49789","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	21
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P49789","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	Site: {"description":"Important for induction of apoptosis","evidences":[{"source":"UniProtKB","id":"P49789","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	6
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P49789","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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