9U6E

FADD-DED filaments coordinate complex IIa assembly during TNF-induced apoptosis

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0001819	biological_process	positive regulation of cytokine production
B	0001822	biological_process	kidney development
B	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
B	0002020	molecular_function	protease binding
B	0002376	biological_process	immune system process
B	0002821	biological_process	positive regulation of adaptive immune response
B	0005123	molecular_function	death receptor binding
B	0005164	molecular_function	tumor necrosis factor receptor binding
B	0005515	molecular_function	protein binding
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0006915	biological_process	apoptotic process
B	0006952	biological_process	defense response
B	0008625	biological_process	extrinsic apoptotic signaling pathway via death domain receptors
B	0009898	cellular_component	cytoplasmic side of plasma membrane
B	0030674	molecular_function	protein-macromolecule adaptor activity
B	0031264	cellular_component	death-inducing signaling complex
B	0031265	cellular_component	CD95 death-inducing signaling complex
B	0032729	biological_process	positive regulation of type II interferon production
B	0032757	biological_process	positive regulation of interleukin-8 production
B	0032760	biological_process	positive regulation of tumor necrosis factor production
B	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
B	0032991	cellular_component	protein-containing complex
B	0033077	biological_process	T cell differentiation in thymus
B	0033612	molecular_function	receptor serine/threonine kinase binding
B	0035591	molecular_function	signaling adaptor activity
B	0035877	molecular_function	death effector domain binding
B	0036462	biological_process	TRAIL-activated apoptotic signaling pathway
B	0042104	biological_process	positive regulation of activated T cell proliferation
B	0042220	biological_process	response to cocaine
B	0042802	molecular_function	identical protein binding
B	0043029	biological_process	T cell homeostasis
B	0043065	biological_process	positive regulation of apoptotic process
B	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
B	0044297	cellular_component	cell body
B	0044877	molecular_function	protein-containing complex binding
B	0045087	biological_process	innate immune response
B	0045089	biological_process	positive regulation of innate immune response
B	0045651	biological_process	positive regulation of macrophage differentiation
B	0045862	biological_process	positive regulation of proteolysis
B	0045944	biological_process	positive regulation of transcription by RNA polymerase II
B	0048148	biological_process	behavioral response to cocaine
B	0048535	biological_process	lymph node development
B	0048536	biological_process	spleen development
B	0048538	biological_process	thymus development
B	0050778	biological_process	positive regulation of immune response
B	0051607	biological_process	defense response to virus
B	0051707	biological_process	response to other organism
B	0060340	biological_process	positive regulation of type I interferon-mediated signaling pathway
B	0060544	biological_process	regulation of necroptotic process
B	0070236	biological_process	negative regulation of activation-induced cell death of T cells
B	0071260	biological_process	cellular response to mechanical stimulus
B	0071550	biological_process	death-inducing signaling complex assembly
B	0089720	molecular_function	caspase binding
B	0097190	biological_process	apoptotic signaling pathway
B	0097191	biological_process	extrinsic apoptotic signaling pathway
B	0097342	cellular_component	ripoptosome
B	0097527	biological_process	necroptotic signaling pathway
B	1900119	biological_process	positive regulation of execution phase of apoptosis
B	2000454	biological_process	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
B	2001238	biological_process	positive regulation of extrinsic apoptotic signaling pathway
C	0001819	biological_process	positive regulation of cytokine production
C	0001822	biological_process	kidney development
C	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
C	0002020	molecular_function	protease binding
C	0002376	biological_process	immune system process
C	0002821	biological_process	positive regulation of adaptive immune response
C	0005123	molecular_function	death receptor binding
C	0005164	molecular_function	tumor necrosis factor receptor binding
C	0005515	molecular_function	protein binding
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0006915	biological_process	apoptotic process
C	0006952	biological_process	defense response
C	0008625	biological_process	extrinsic apoptotic signaling pathway via death domain receptors
C	0009898	cellular_component	cytoplasmic side of plasma membrane
C	0030674	molecular_function	protein-macromolecule adaptor activity
C	0031264	cellular_component	death-inducing signaling complex
C	0031265	cellular_component	CD95 death-inducing signaling complex
C	0032729	biological_process	positive regulation of type II interferon production
C	0032757	biological_process	positive regulation of interleukin-8 production
C	0032760	biological_process	positive regulation of tumor necrosis factor production
C	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
C	0032991	cellular_component	protein-containing complex
C	0033077	biological_process	T cell differentiation in thymus
C	0033612	molecular_function	receptor serine/threonine kinase binding
C	0035591	molecular_function	signaling adaptor activity
C	0035877	molecular_function	death effector domain binding
C	0036462	biological_process	TRAIL-activated apoptotic signaling pathway
C	0042104	biological_process	positive regulation of activated T cell proliferation
C	0042220	biological_process	response to cocaine
C	0042802	molecular_function	identical protein binding
C	0043029	biological_process	T cell homeostasis
C	0043065	biological_process	positive regulation of apoptotic process
C	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
C	0044297	cellular_component	cell body
C	0044877	molecular_function	protein-containing complex binding
C	0045087	biological_process	innate immune response
C	0045089	biological_process	positive regulation of innate immune response
C	0045651	biological_process	positive regulation of macrophage differentiation
C	0045862	biological_process	positive regulation of proteolysis
C	0045944	biological_process	positive regulation of transcription by RNA polymerase II
C	0048148	biological_process	behavioral response to cocaine
C	0048535	biological_process	lymph node development
C	0048536	biological_process	spleen development
C	0048538	biological_process	thymus development
C	0050778	biological_process	positive regulation of immune response
C	0051607	biological_process	defense response to virus
C	0051707	biological_process	response to other organism
C	0060340	biological_process	positive regulation of type I interferon-mediated signaling pathway
C	0060544	biological_process	regulation of necroptotic process
C	0070236	biological_process	negative regulation of activation-induced cell death of T cells
C	0071260	biological_process	cellular response to mechanical stimulus
C	0071550	biological_process	death-inducing signaling complex assembly
C	0089720	molecular_function	caspase binding
C	0097190	biological_process	apoptotic signaling pathway
C	0097191	biological_process	extrinsic apoptotic signaling pathway
C	0097342	cellular_component	ripoptosome
C	0097527	biological_process	necroptotic signaling pathway
C	1900119	biological_process	positive regulation of execution phase of apoptosis
C	2000454	biological_process	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
C	2001238	biological_process	positive regulation of extrinsic apoptotic signaling pathway
D	0001819	biological_process	positive regulation of cytokine production
D	0001822	biological_process	kidney development
D	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
D	0002020	molecular_function	protease binding
D	0002376	biological_process	immune system process
D	0002821	biological_process	positive regulation of adaptive immune response
D	0005123	molecular_function	death receptor binding
D	0005164	molecular_function	tumor necrosis factor receptor binding
D	0005515	molecular_function	protein binding
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0006915	biological_process	apoptotic process
D	0006952	biological_process	defense response
D	0008625	biological_process	extrinsic apoptotic signaling pathway via death domain receptors
D	0009898	cellular_component	cytoplasmic side of plasma membrane
D	0030674	molecular_function	protein-macromolecule adaptor activity
D	0031264	cellular_component	death-inducing signaling complex
D	0031265	cellular_component	CD95 death-inducing signaling complex
D	0032729	biological_process	positive regulation of type II interferon production
D	0032757	biological_process	positive regulation of interleukin-8 production
D	0032760	biological_process	positive regulation of tumor necrosis factor production
D	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
D	0032991	cellular_component	protein-containing complex
D	0033077	biological_process	T cell differentiation in thymus
D	0033612	molecular_function	receptor serine/threonine kinase binding
D	0035591	molecular_function	signaling adaptor activity
D	0035877	molecular_function	death effector domain binding
D	0036462	biological_process	TRAIL-activated apoptotic signaling pathway
D	0042104	biological_process	positive regulation of activated T cell proliferation
D	0042220	biological_process	response to cocaine
D	0042802	molecular_function	identical protein binding
D	0043029	biological_process	T cell homeostasis
D	0043065	biological_process	positive regulation of apoptotic process
D	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
D	0044297	cellular_component	cell body
D	0044877	molecular_function	protein-containing complex binding
D	0045087	biological_process	innate immune response
D	0045089	biological_process	positive regulation of innate immune response
D	0045651	biological_process	positive regulation of macrophage differentiation
D	0045862	biological_process	positive regulation of proteolysis
D	0045944	biological_process	positive regulation of transcription by RNA polymerase II
D	0048148	biological_process	behavioral response to cocaine
D	0048535	biological_process	lymph node development
D	0048536	biological_process	spleen development
D	0048538	biological_process	thymus development
D	0050778	biological_process	positive regulation of immune response
D	0051607	biological_process	defense response to virus
D	0051707	biological_process	response to other organism
D	0060340	biological_process	positive regulation of type I interferon-mediated signaling pathway
D	0060544	biological_process	regulation of necroptotic process
D	0070236	biological_process	negative regulation of activation-induced cell death of T cells
D	0071260	biological_process	cellular response to mechanical stimulus
D	0071550	biological_process	death-inducing signaling complex assembly
D	0089720	molecular_function	caspase binding
D	0097190	biological_process	apoptotic signaling pathway
D	0097191	biological_process	extrinsic apoptotic signaling pathway
D	0097342	cellular_component	ripoptosome
D	0097527	biological_process	necroptotic signaling pathway
D	1900119	biological_process	positive regulation of execution phase of apoptosis
D	2000454	biological_process	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
D	2001238	biological_process	positive regulation of extrinsic apoptotic signaling pathway
E	0001819	biological_process	positive regulation of cytokine production
E	0001822	biological_process	kidney development
E	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
E	0002020	molecular_function	protease binding
E	0002376	biological_process	immune system process
E	0002821	biological_process	positive regulation of adaptive immune response
E	0005123	molecular_function	death receptor binding
E	0005164	molecular_function	tumor necrosis factor receptor binding
E	0005515	molecular_function	protein binding
E	0005654	cellular_component	nucleoplasm
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005886	cellular_component	plasma membrane
E	0006915	biological_process	apoptotic process
E	0006952	biological_process	defense response
E	0008625	biological_process	extrinsic apoptotic signaling pathway via death domain receptors
E	0009898	cellular_component	cytoplasmic side of plasma membrane
E	0030674	molecular_function	protein-macromolecule adaptor activity
E	0031264	cellular_component	death-inducing signaling complex
E	0031265	cellular_component	CD95 death-inducing signaling complex
E	0032729	biological_process	positive regulation of type II interferon production
E	0032757	biological_process	positive regulation of interleukin-8 production
E	0032760	biological_process	positive regulation of tumor necrosis factor production
E	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
E	0032991	cellular_component	protein-containing complex
E	0033077	biological_process	T cell differentiation in thymus
E	0033612	molecular_function	receptor serine/threonine kinase binding
E	0035591	molecular_function	signaling adaptor activity
E	0035877	molecular_function	death effector domain binding
E	0036462	biological_process	TRAIL-activated apoptotic signaling pathway
E	0042104	biological_process	positive regulation of activated T cell proliferation
E	0042220	biological_process	response to cocaine
E	0042802	molecular_function	identical protein binding
E	0043029	biological_process	T cell homeostasis
E	0043065	biological_process	positive regulation of apoptotic process
E	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
E	0044297	cellular_component	cell body
E	0044877	molecular_function	protein-containing complex binding
E	0045087	biological_process	innate immune response
E	0045089	biological_process	positive regulation of innate immune response
E	0045651	biological_process	positive regulation of macrophage differentiation
E	0045862	biological_process	positive regulation of proteolysis
E	0045944	biological_process	positive regulation of transcription by RNA polymerase II
E	0048148	biological_process	behavioral response to cocaine
E	0048535	biological_process	lymph node development
E	0048536	biological_process	spleen development
E	0048538	biological_process	thymus development
E	0050778	biological_process	positive regulation of immune response
E	0051607	biological_process	defense response to virus
E	0051707	biological_process	response to other organism
E	0060340	biological_process	positive regulation of type I interferon-mediated signaling pathway
E	0060544	biological_process	regulation of necroptotic process
E	0070236	biological_process	negative regulation of activation-induced cell death of T cells
E	0071260	biological_process	cellular response to mechanical stimulus
E	0071550	biological_process	death-inducing signaling complex assembly
E	0089720	molecular_function	caspase binding
E	0097190	biological_process	apoptotic signaling pathway
E	0097191	biological_process	extrinsic apoptotic signaling pathway
E	0097342	cellular_component	ripoptosome
E	0097527	biological_process	necroptotic signaling pathway
E	1900119	biological_process	positive regulation of execution phase of apoptosis
E	2000454	biological_process	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
E	2001238	biological_process	positive regulation of extrinsic apoptotic signaling pathway
F	0001819	biological_process	positive regulation of cytokine production
F	0001822	biological_process	kidney development
F	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
F	0002020	molecular_function	protease binding
F	0002376	biological_process	immune system process
F	0002821	biological_process	positive regulation of adaptive immune response
F	0005123	molecular_function	death receptor binding
F	0005164	molecular_function	tumor necrosis factor receptor binding
F	0005515	molecular_function	protein binding
F	0005654	cellular_component	nucleoplasm
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0005886	cellular_component	plasma membrane
F	0006915	biological_process	apoptotic process
F	0006952	biological_process	defense response
F	0008625	biological_process	extrinsic apoptotic signaling pathway via death domain receptors
F	0009898	cellular_component	cytoplasmic side of plasma membrane
F	0030674	molecular_function	protein-macromolecule adaptor activity
F	0031264	cellular_component	death-inducing signaling complex
F	0031265	cellular_component	CD95 death-inducing signaling complex
F	0032729	biological_process	positive regulation of type II interferon production
F	0032757	biological_process	positive regulation of interleukin-8 production
F	0032760	biological_process	positive regulation of tumor necrosis factor production
F	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
F	0032991	cellular_component	protein-containing complex
F	0033077	biological_process	T cell differentiation in thymus
F	0033612	molecular_function	receptor serine/threonine kinase binding
F	0035591	molecular_function	signaling adaptor activity
F	0035877	molecular_function	death effector domain binding
F	0036462	biological_process	TRAIL-activated apoptotic signaling pathway
F	0042104	biological_process	positive regulation of activated T cell proliferation
F	0042220	biological_process	response to cocaine
F	0042802	molecular_function	identical protein binding
F	0043029	biological_process	T cell homeostasis
F	0043065	biological_process	positive regulation of apoptotic process
F	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
F	0044297	cellular_component	cell body
F	0044877	molecular_function	protein-containing complex binding
F	0045087	biological_process	innate immune response
F	0045089	biological_process	positive regulation of innate immune response
F	0045651	biological_process	positive regulation of macrophage differentiation
F	0045862	biological_process	positive regulation of proteolysis
F	0045944	biological_process	positive regulation of transcription by RNA polymerase II
F	0048148	biological_process	behavioral response to cocaine
F	0048535	biological_process	lymph node development
F	0048536	biological_process	spleen development
F	0048538	biological_process	thymus development
F	0050778	biological_process	positive regulation of immune response
F	0051607	biological_process	defense response to virus
F	0051707	biological_process	response to other organism
F	0060340	biological_process	positive regulation of type I interferon-mediated signaling pathway
F	0060544	biological_process	regulation of necroptotic process
F	0070236	biological_process	negative regulation of activation-induced cell death of T cells
F	0071260	biological_process	cellular response to mechanical stimulus
F	0071550	biological_process	death-inducing signaling complex assembly
F	0089720	molecular_function	caspase binding
F	0097190	biological_process	apoptotic signaling pathway
F	0097191	biological_process	extrinsic apoptotic signaling pathway
F	0097342	cellular_component	ripoptosome
F	0097527	biological_process	necroptotic signaling pathway
F	1900119	biological_process	positive regulation of execution phase of apoptosis
F	2000454	biological_process	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
F	2001238	biological_process	positive regulation of extrinsic apoptotic signaling pathway
G	0001819	biological_process	positive regulation of cytokine production
G	0001822	biological_process	kidney development
G	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
G	0002020	molecular_function	protease binding
G	0002376	biological_process	immune system process
G	0002821	biological_process	positive regulation of adaptive immune response
G	0005123	molecular_function	death receptor binding
G	0005164	molecular_function	tumor necrosis factor receptor binding
G	0005515	molecular_function	protein binding
G	0005654	cellular_component	nucleoplasm
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0005886	cellular_component	plasma membrane
G	0006915	biological_process	apoptotic process
G	0006952	biological_process	defense response
G	0008625	biological_process	extrinsic apoptotic signaling pathway via death domain receptors
G	0009898	cellular_component	cytoplasmic side of plasma membrane
G	0030674	molecular_function	protein-macromolecule adaptor activity
G	0031264	cellular_component	death-inducing signaling complex
G	0031265	cellular_component	CD95 death-inducing signaling complex
G	0032729	biological_process	positive regulation of type II interferon production
G	0032757	biological_process	positive regulation of interleukin-8 production
G	0032760	biological_process	positive regulation of tumor necrosis factor production
G	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
G	0032991	cellular_component	protein-containing complex
G	0033077	biological_process	T cell differentiation in thymus
G	0033612	molecular_function	receptor serine/threonine kinase binding
G	0035591	molecular_function	signaling adaptor activity
G	0035877	molecular_function	death effector domain binding
G	0036462	biological_process	TRAIL-activated apoptotic signaling pathway
G	0042104	biological_process	positive regulation of activated T cell proliferation
G	0042220	biological_process	response to cocaine
G	0042802	molecular_function	identical protein binding
G	0043029	biological_process	T cell homeostasis
G	0043065	biological_process	positive regulation of apoptotic process
G	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
G	0044297	cellular_component	cell body
G	0044877	molecular_function	protein-containing complex binding
G	0045087	biological_process	innate immune response
G	0045089	biological_process	positive regulation of innate immune response
G	0045651	biological_process	positive regulation of macrophage differentiation
G	0045862	biological_process	positive regulation of proteolysis
G	0045944	biological_process	positive regulation of transcription by RNA polymerase II
G	0048148	biological_process	behavioral response to cocaine
G	0048535	biological_process	lymph node development
G	0048536	biological_process	spleen development
G	0048538	biological_process	thymus development
G	0050778	biological_process	positive regulation of immune response
G	0051607	biological_process	defense response to virus
G	0051707	biological_process	response to other organism
G	0060340	biological_process	positive regulation of type I interferon-mediated signaling pathway
G	0060544	biological_process	regulation of necroptotic process
G	0070236	biological_process	negative regulation of activation-induced cell death of T cells
G	0071260	biological_process	cellular response to mechanical stimulus
G	0071550	biological_process	death-inducing signaling complex assembly
G	0089720	molecular_function	caspase binding
G	0097190	biological_process	apoptotic signaling pathway
G	0097191	biological_process	extrinsic apoptotic signaling pathway
G	0097342	cellular_component	ripoptosome
G	0097527	biological_process	necroptotic signaling pathway
G	1900119	biological_process	positive regulation of execution phase of apoptosis
G	2000454	biological_process	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
G	2001238	biological_process	positive regulation of extrinsic apoptotic signaling pathway
H	0001819	biological_process	positive regulation of cytokine production
H	0001822	biological_process	kidney development
H	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
H	0002020	molecular_function	protease binding
H	0002376	biological_process	immune system process
H	0002821	biological_process	positive regulation of adaptive immune response
H	0005123	molecular_function	death receptor binding
H	0005164	molecular_function	tumor necrosis factor receptor binding
H	0005515	molecular_function	protein binding
H	0005654	cellular_component	nucleoplasm
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0005886	cellular_component	plasma membrane
H	0006915	biological_process	apoptotic process
H	0006952	biological_process	defense response
H	0008625	biological_process	extrinsic apoptotic signaling pathway via death domain receptors
H	0009898	cellular_component	cytoplasmic side of plasma membrane
H	0030674	molecular_function	protein-macromolecule adaptor activity
H	0031264	cellular_component	death-inducing signaling complex
H	0031265	cellular_component	CD95 death-inducing signaling complex
H	0032729	biological_process	positive regulation of type II interferon production
H	0032757	biological_process	positive regulation of interleukin-8 production
H	0032760	biological_process	positive regulation of tumor necrosis factor production
H	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
H	0032991	cellular_component	protein-containing complex
H	0033077	biological_process	T cell differentiation in thymus
H	0033612	molecular_function	receptor serine/threonine kinase binding
H	0035591	molecular_function	signaling adaptor activity
H	0035877	molecular_function	death effector domain binding
H	0036462	biological_process	TRAIL-activated apoptotic signaling pathway
H	0042104	biological_process	positive regulation of activated T cell proliferation
H	0042220	biological_process	response to cocaine
H	0042802	molecular_function	identical protein binding
H	0043029	biological_process	T cell homeostasis
H	0043065	biological_process	positive regulation of apoptotic process
H	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
H	0044297	cellular_component	cell body
H	0044877	molecular_function	protein-containing complex binding
H	0045087	biological_process	innate immune response
H	0045089	biological_process	positive regulation of innate immune response
H	0045651	biological_process	positive regulation of macrophage differentiation
H	0045862	biological_process	positive regulation of proteolysis
H	0045944	biological_process	positive regulation of transcription by RNA polymerase II
H	0048148	biological_process	behavioral response to cocaine
H	0048535	biological_process	lymph node development
H	0048536	biological_process	spleen development
H	0048538	biological_process	thymus development
H	0050778	biological_process	positive regulation of immune response
H	0051607	biological_process	defense response to virus
H	0051707	biological_process	response to other organism
H	0060340	biological_process	positive regulation of type I interferon-mediated signaling pathway
H	0060544	biological_process	regulation of necroptotic process
H	0070236	biological_process	negative regulation of activation-induced cell death of T cells
H	0071260	biological_process	cellular response to mechanical stimulus
H	0071550	biological_process	death-inducing signaling complex assembly
H	0089720	molecular_function	caspase binding
H	0097190	biological_process	apoptotic signaling pathway
H	0097191	biological_process	extrinsic apoptotic signaling pathway
H	0097342	cellular_component	ripoptosome
H	0097527	biological_process	necroptotic signaling pathway
H	1900119	biological_process	positive regulation of execution phase of apoptosis
H	2000454	biological_process	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
H	2001238	biological_process	positive regulation of extrinsic apoptotic signaling pathway
I	0001819	biological_process	positive regulation of cytokine production
I	0001822	biological_process	kidney development
I	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
I	0002020	molecular_function	protease binding
I	0002376	biological_process	immune system process
I	0002821	biological_process	positive regulation of adaptive immune response
I	0005123	molecular_function	death receptor binding
I	0005164	molecular_function	tumor necrosis factor receptor binding
I	0005515	molecular_function	protein binding
I	0005654	cellular_component	nucleoplasm
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0005886	cellular_component	plasma membrane
I	0006915	biological_process	apoptotic process
I	0006952	biological_process	defense response
I	0008625	biological_process	extrinsic apoptotic signaling pathway via death domain receptors
I	0009898	cellular_component	cytoplasmic side of plasma membrane
I	0030674	molecular_function	protein-macromolecule adaptor activity
I	0031264	cellular_component	death-inducing signaling complex
I	0031265	cellular_component	CD95 death-inducing signaling complex
I	0032729	biological_process	positive regulation of type II interferon production
I	0032757	biological_process	positive regulation of interleukin-8 production
I	0032760	biological_process	positive regulation of tumor necrosis factor production
I	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
I	0032991	cellular_component	protein-containing complex
I	0033077	biological_process	T cell differentiation in thymus
I	0033612	molecular_function	receptor serine/threonine kinase binding
I	0035591	molecular_function	signaling adaptor activity
I	0035877	molecular_function	death effector domain binding
I	0036462	biological_process	TRAIL-activated apoptotic signaling pathway
I	0042104	biological_process	positive regulation of activated T cell proliferation
I	0042220	biological_process	response to cocaine
I	0042802	molecular_function	identical protein binding
I	0043029	biological_process	T cell homeostasis
I	0043065	biological_process	positive regulation of apoptotic process
I	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
I	0044297	cellular_component	cell body
I	0044877	molecular_function	protein-containing complex binding
I	0045087	biological_process	innate immune response
I	0045089	biological_process	positive regulation of innate immune response
I	0045651	biological_process	positive regulation of macrophage differentiation
I	0045862	biological_process	positive regulation of proteolysis
I	0045944	biological_process	positive regulation of transcription by RNA polymerase II
I	0048148	biological_process	behavioral response to cocaine
I	0048535	biological_process	lymph node development
I	0048536	biological_process	spleen development
I	0048538	biological_process	thymus development
I	0050778	biological_process	positive regulation of immune response
I	0051607	biological_process	defense response to virus
I	0051707	biological_process	response to other organism
I	0060340	biological_process	positive regulation of type I interferon-mediated signaling pathway
I	0060544	biological_process	regulation of necroptotic process
I	0070236	biological_process	negative regulation of activation-induced cell death of T cells
I	0071260	biological_process	cellular response to mechanical stimulus
I	0071550	biological_process	death-inducing signaling complex assembly
I	0089720	molecular_function	caspase binding
I	0097190	biological_process	apoptotic signaling pathway
I	0097191	biological_process	extrinsic apoptotic signaling pathway
I	0097342	cellular_component	ripoptosome
I	0097527	biological_process	necroptotic signaling pathway
I	1900119	biological_process	positive regulation of execution phase of apoptosis
I	2000454	biological_process	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
I	2001238	biological_process	positive regulation of extrinsic apoptotic signaling pathway
J	0001819	biological_process	positive regulation of cytokine production
J	0001822	biological_process	kidney development
J	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
J	0002020	molecular_function	protease binding
J	0002376	biological_process	immune system process
J	0002821	biological_process	positive regulation of adaptive immune response
J	0005123	molecular_function	death receptor binding
J	0005164	molecular_function	tumor necrosis factor receptor binding
J	0005515	molecular_function	protein binding
J	0005654	cellular_component	nucleoplasm
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0005886	cellular_component	plasma membrane
J	0006915	biological_process	apoptotic process
J	0006952	biological_process	defense response
J	0008625	biological_process	extrinsic apoptotic signaling pathway via death domain receptors
J	0009898	cellular_component	cytoplasmic side of plasma membrane
J	0030674	molecular_function	protein-macromolecule adaptor activity
J	0031264	cellular_component	death-inducing signaling complex
J	0031265	cellular_component	CD95 death-inducing signaling complex
J	0032729	biological_process	positive regulation of type II interferon production
J	0032757	biological_process	positive regulation of interleukin-8 production
J	0032760	biological_process	positive regulation of tumor necrosis factor production
J	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
J	0032991	cellular_component	protein-containing complex
J	0033077	biological_process	T cell differentiation in thymus
J	0033612	molecular_function	receptor serine/threonine kinase binding
J	0035591	molecular_function	signaling adaptor activity
J	0035877	molecular_function	death effector domain binding
J	0036462	biological_process	TRAIL-activated apoptotic signaling pathway
J	0042104	biological_process	positive regulation of activated T cell proliferation
J	0042220	biological_process	response to cocaine
J	0042802	molecular_function	identical protein binding
J	0043029	biological_process	T cell homeostasis
J	0043065	biological_process	positive regulation of apoptotic process
J	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
J	0044297	cellular_component	cell body
J	0044877	molecular_function	protein-containing complex binding
J	0045087	biological_process	innate immune response
J	0045089	biological_process	positive regulation of innate immune response
J	0045651	biological_process	positive regulation of macrophage differentiation
J	0045862	biological_process	positive regulation of proteolysis
J	0045944	biological_process	positive regulation of transcription by RNA polymerase II
J	0048148	biological_process	behavioral response to cocaine
J	0048535	biological_process	lymph node development
J	0048536	biological_process	spleen development
J	0048538	biological_process	thymus development
J	0050778	biological_process	positive regulation of immune response
J	0051607	biological_process	defense response to virus
J	0051707	biological_process	response to other organism
J	0060340	biological_process	positive regulation of type I interferon-mediated signaling pathway
J	0060544	biological_process	regulation of necroptotic process
J	0070236	biological_process	negative regulation of activation-induced cell death of T cells
J	0071260	biological_process	cellular response to mechanical stimulus
J	0071550	biological_process	death-inducing signaling complex assembly
J	0089720	molecular_function	caspase binding
J	0097190	biological_process	apoptotic signaling pathway
J	0097191	biological_process	extrinsic apoptotic signaling pathway
J	0097342	cellular_component	ripoptosome
J	0097527	biological_process	necroptotic signaling pathway
J	1900119	biological_process	positive regulation of execution phase of apoptosis
J	2000454	biological_process	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
J	2001238	biological_process	positive regulation of extrinsic apoptotic signaling pathway
K	0001819	biological_process	positive regulation of cytokine production
K	0001822	biological_process	kidney development
K	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
K	0002020	molecular_function	protease binding
K	0002376	biological_process	immune system process
K	0002821	biological_process	positive regulation of adaptive immune response
K	0005123	molecular_function	death receptor binding
K	0005164	molecular_function	tumor necrosis factor receptor binding
K	0005515	molecular_function	protein binding
K	0005654	cellular_component	nucleoplasm
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0005886	cellular_component	plasma membrane
K	0006915	biological_process	apoptotic process
K	0006952	biological_process	defense response
K	0008625	biological_process	extrinsic apoptotic signaling pathway via death domain receptors
K	0009898	cellular_component	cytoplasmic side of plasma membrane
K	0030674	molecular_function	protein-macromolecule adaptor activity
K	0031264	cellular_component	death-inducing signaling complex
K	0031265	cellular_component	CD95 death-inducing signaling complex
K	0032729	biological_process	positive regulation of type II interferon production
K	0032757	biological_process	positive regulation of interleukin-8 production
K	0032760	biological_process	positive regulation of tumor necrosis factor production
K	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
K	0032991	cellular_component	protein-containing complex
K	0033077	biological_process	T cell differentiation in thymus
K	0033612	molecular_function	receptor serine/threonine kinase binding
K	0035591	molecular_function	signaling adaptor activity
K	0035877	molecular_function	death effector domain binding
K	0036462	biological_process	TRAIL-activated apoptotic signaling pathway
K	0042104	biological_process	positive regulation of activated T cell proliferation
K	0042220	biological_process	response to cocaine
K	0042802	molecular_function	identical protein binding
K	0043029	biological_process	T cell homeostasis
K	0043065	biological_process	positive regulation of apoptotic process
K	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
K	0044297	cellular_component	cell body
K	0044877	molecular_function	protein-containing complex binding
K	0045087	biological_process	innate immune response
K	0045089	biological_process	positive regulation of innate immune response
K	0045651	biological_process	positive regulation of macrophage differentiation
K	0045862	biological_process	positive regulation of proteolysis
K	0045944	biological_process	positive regulation of transcription by RNA polymerase II
K	0048148	biological_process	behavioral response to cocaine
K	0048535	biological_process	lymph node development
K	0048536	biological_process	spleen development
K	0048538	biological_process	thymus development
K	0050778	biological_process	positive regulation of immune response
K	0051607	biological_process	defense response to virus
K	0051707	biological_process	response to other organism
K	0060340	biological_process	positive regulation of type I interferon-mediated signaling pathway
K	0060544	biological_process	regulation of necroptotic process
K	0070236	biological_process	negative regulation of activation-induced cell death of T cells
K	0071260	biological_process	cellular response to mechanical stimulus
K	0071550	biological_process	death-inducing signaling complex assembly
K	0089720	molecular_function	caspase binding
K	0097190	biological_process	apoptotic signaling pathway
K	0097191	biological_process	extrinsic apoptotic signaling pathway
K	0097342	cellular_component	ripoptosome
K	0097527	biological_process	necroptotic signaling pathway
K	1900119	biological_process	positive regulation of execution phase of apoptosis
K	2000454	biological_process	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
K	2001238	biological_process	positive regulation of extrinsic apoptotic signaling pathway
L	0001819	biological_process	positive regulation of cytokine production
L	0001822	biological_process	kidney development
L	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
L	0002020	molecular_function	protease binding
L	0002376	biological_process	immune system process
L	0002821	biological_process	positive regulation of adaptive immune response
L	0005123	molecular_function	death receptor binding
L	0005164	molecular_function	tumor necrosis factor receptor binding
L	0005515	molecular_function	protein binding
L	0005654	cellular_component	nucleoplasm
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0005886	cellular_component	plasma membrane
L	0006915	biological_process	apoptotic process
L	0006952	biological_process	defense response
L	0008625	biological_process	extrinsic apoptotic signaling pathway via death domain receptors
L	0009898	cellular_component	cytoplasmic side of plasma membrane
L	0030674	molecular_function	protein-macromolecule adaptor activity
L	0031264	cellular_component	death-inducing signaling complex
L	0031265	cellular_component	CD95 death-inducing signaling complex
L	0032729	biological_process	positive regulation of type II interferon production
L	0032757	biological_process	positive regulation of interleukin-8 production
L	0032760	biological_process	positive regulation of tumor necrosis factor production
L	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
L	0032991	cellular_component	protein-containing complex
L	0033077	biological_process	T cell differentiation in thymus
L	0033612	molecular_function	receptor serine/threonine kinase binding
L	0035591	molecular_function	signaling adaptor activity
L	0035877	molecular_function	death effector domain binding
L	0036462	biological_process	TRAIL-activated apoptotic signaling pathway
L	0042104	biological_process	positive regulation of activated T cell proliferation
L	0042220	biological_process	response to cocaine
L	0042802	molecular_function	identical protein binding
L	0043029	biological_process	T cell homeostasis
L	0043065	biological_process	positive regulation of apoptotic process
L	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
L	0044297	cellular_component	cell body
L	0044877	molecular_function	protein-containing complex binding
L	0045087	biological_process	innate immune response
L	0045089	biological_process	positive regulation of innate immune response
L	0045651	biological_process	positive regulation of macrophage differentiation
L	0045862	biological_process	positive regulation of proteolysis
L	0045944	biological_process	positive regulation of transcription by RNA polymerase II
L	0048148	biological_process	behavioral response to cocaine
L	0048535	biological_process	lymph node development
L	0048536	biological_process	spleen development
L	0048538	biological_process	thymus development
L	0050778	biological_process	positive regulation of immune response
L	0051607	biological_process	defense response to virus
L	0051707	biological_process	response to other organism
L	0060340	biological_process	positive regulation of type I interferon-mediated signaling pathway
L	0060544	biological_process	regulation of necroptotic process
L	0070236	biological_process	negative regulation of activation-induced cell death of T cells
L	0071260	biological_process	cellular response to mechanical stimulus
L	0071550	biological_process	death-inducing signaling complex assembly
L	0089720	molecular_function	caspase binding
L	0097190	biological_process	apoptotic signaling pathway
L	0097191	biological_process	extrinsic apoptotic signaling pathway
L	0097342	cellular_component	ripoptosome
L	0097527	biological_process	necroptotic signaling pathway
L	1900119	biological_process	positive regulation of execution phase of apoptosis
L	2000454	biological_process	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
L	2001238	biological_process	positive regulation of extrinsic apoptotic signaling pathway
M	0001819	biological_process	positive regulation of cytokine production
M	0001822	biological_process	kidney development
M	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
M	0002020	molecular_function	protease binding
M	0002376	biological_process	immune system process
M	0002821	biological_process	positive regulation of adaptive immune response
M	0005123	molecular_function	death receptor binding
M	0005164	molecular_function	tumor necrosis factor receptor binding
M	0005515	molecular_function	protein binding
M	0005654	cellular_component	nucleoplasm
M	0005737	cellular_component	cytoplasm
M	0005829	cellular_component	cytosol
M	0005886	cellular_component	plasma membrane
M	0006915	biological_process	apoptotic process
M	0006952	biological_process	defense response
M	0008625	biological_process	extrinsic apoptotic signaling pathway via death domain receptors
M	0009898	cellular_component	cytoplasmic side of plasma membrane
M	0030674	molecular_function	protein-macromolecule adaptor activity
M	0031264	cellular_component	death-inducing signaling complex
M	0031265	cellular_component	CD95 death-inducing signaling complex
M	0032729	biological_process	positive regulation of type II interferon production
M	0032757	biological_process	positive regulation of interleukin-8 production
M	0032760	biological_process	positive regulation of tumor necrosis factor production
M	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
M	0032991	cellular_component	protein-containing complex
M	0033077	biological_process	T cell differentiation in thymus
M	0033612	molecular_function	receptor serine/threonine kinase binding
M	0035591	molecular_function	signaling adaptor activity
M	0035877	molecular_function	death effector domain binding
M	0036462	biological_process	TRAIL-activated apoptotic signaling pathway
M	0042104	biological_process	positive regulation of activated T cell proliferation
M	0042220	biological_process	response to cocaine
M	0042802	molecular_function	identical protein binding
M	0043029	biological_process	T cell homeostasis
M	0043065	biological_process	positive regulation of apoptotic process
M	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
M	0044297	cellular_component	cell body
M	0044877	molecular_function	protein-containing complex binding
M	0045087	biological_process	innate immune response
M	0045089	biological_process	positive regulation of innate immune response
M	0045651	biological_process	positive regulation of macrophage differentiation
M	0045862	biological_process	positive regulation of proteolysis
M	0045944	biological_process	positive regulation of transcription by RNA polymerase II
M	0048148	biological_process	behavioral response to cocaine
M	0048535	biological_process	lymph node development
M	0048536	biological_process	spleen development
M	0048538	biological_process	thymus development
M	0050778	biological_process	positive regulation of immune response
M	0051607	biological_process	defense response to virus
M	0051707	biological_process	response to other organism
M	0060340	biological_process	positive regulation of type I interferon-mediated signaling pathway
M	0060544	biological_process	regulation of necroptotic process
M	0070236	biological_process	negative regulation of activation-induced cell death of T cells
M	0071260	biological_process	cellular response to mechanical stimulus
M	0071550	biological_process	death-inducing signaling complex assembly
M	0089720	molecular_function	caspase binding
M	0097190	biological_process	apoptotic signaling pathway
M	0097191	biological_process	extrinsic apoptotic signaling pathway
M	0097342	cellular_component	ripoptosome
M	0097527	biological_process	necroptotic signaling pathway
M	1900119	biological_process	positive regulation of execution phase of apoptosis
M	2000454	biological_process	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
M	2001238	biological_process	positive regulation of extrinsic apoptotic signaling pathway
N	0001819	biological_process	positive regulation of cytokine production
N	0001822	biological_process	kidney development
N	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
N	0002020	molecular_function	protease binding
N	0002376	biological_process	immune system process
N	0002821	biological_process	positive regulation of adaptive immune response
N	0005123	molecular_function	death receptor binding
N	0005164	molecular_function	tumor necrosis factor receptor binding
N	0005515	molecular_function	protein binding
N	0005654	cellular_component	nucleoplasm
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0005886	cellular_component	plasma membrane
N	0006915	biological_process	apoptotic process
N	0006952	biological_process	defense response
N	0008625	biological_process	extrinsic apoptotic signaling pathway via death domain receptors
N	0009898	cellular_component	cytoplasmic side of plasma membrane
N	0030674	molecular_function	protein-macromolecule adaptor activity
N	0031264	cellular_component	death-inducing signaling complex
N	0031265	cellular_component	CD95 death-inducing signaling complex
N	0032729	biological_process	positive regulation of type II interferon production
N	0032757	biological_process	positive regulation of interleukin-8 production
N	0032760	biological_process	positive regulation of tumor necrosis factor production
N	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
N	0032991	cellular_component	protein-containing complex
N	0033077	biological_process	T cell differentiation in thymus
N	0033612	molecular_function	receptor serine/threonine kinase binding
N	0035591	molecular_function	signaling adaptor activity
N	0035877	molecular_function	death effector domain binding
N	0036462	biological_process	TRAIL-activated apoptotic signaling pathway
N	0042104	biological_process	positive regulation of activated T cell proliferation
N	0042220	biological_process	response to cocaine
N	0042802	molecular_function	identical protein binding
N	0043029	biological_process	T cell homeostasis
N	0043065	biological_process	positive regulation of apoptotic process
N	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
N	0044297	cellular_component	cell body
N	0044877	molecular_function	protein-containing complex binding
N	0045087	biological_process	innate immune response
N	0045089	biological_process	positive regulation of innate immune response
N	0045651	biological_process	positive regulation of macrophage differentiation
N	0045862	biological_process	positive regulation of proteolysis
N	0045944	biological_process	positive regulation of transcription by RNA polymerase II
N	0048148	biological_process	behavioral response to cocaine
N	0048535	biological_process	lymph node development
N	0048536	biological_process	spleen development
N	0048538	biological_process	thymus development
N	0050778	biological_process	positive regulation of immune response
N	0051607	biological_process	defense response to virus
N	0051707	biological_process	response to other organism
N	0060340	biological_process	positive regulation of type I interferon-mediated signaling pathway
N	0060544	biological_process	regulation of necroptotic process
N	0070236	biological_process	negative regulation of activation-induced cell death of T cells
N	0071260	biological_process	cellular response to mechanical stimulus
N	0071550	biological_process	death-inducing signaling complex assembly
N	0089720	molecular_function	caspase binding
N	0097190	biological_process	apoptotic signaling pathway
N	0097191	biological_process	extrinsic apoptotic signaling pathway
N	0097342	cellular_component	ripoptosome
N	0097527	biological_process	necroptotic signaling pathway
N	1900119	biological_process	positive regulation of execution phase of apoptosis
N	2000454	biological_process	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
N	2001238	biological_process	positive regulation of extrinsic apoptotic signaling pathway
O	0001819	biological_process	positive regulation of cytokine production
O	0001822	biological_process	kidney development
O	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
O	0002020	molecular_function	protease binding
O	0002376	biological_process	immune system process
O	0002821	biological_process	positive regulation of adaptive immune response
O	0005123	molecular_function	death receptor binding
O	0005164	molecular_function	tumor necrosis factor receptor binding
O	0005515	molecular_function	protein binding
O	0005654	cellular_component	nucleoplasm
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0005886	cellular_component	plasma membrane
O	0006915	biological_process	apoptotic process
O	0006952	biological_process	defense response
O	0008625	biological_process	extrinsic apoptotic signaling pathway via death domain receptors
O	0009898	cellular_component	cytoplasmic side of plasma membrane
O	0030674	molecular_function	protein-macromolecule adaptor activity
O	0031264	cellular_component	death-inducing signaling complex
O	0031265	cellular_component	CD95 death-inducing signaling complex
O	0032729	biological_process	positive regulation of type II interferon production
O	0032757	biological_process	positive regulation of interleukin-8 production
O	0032760	biological_process	positive regulation of tumor necrosis factor production
O	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
O	0032991	cellular_component	protein-containing complex
O	0033077	biological_process	T cell differentiation in thymus
O	0033612	molecular_function	receptor serine/threonine kinase binding
O	0035591	molecular_function	signaling adaptor activity
O	0035877	molecular_function	death effector domain binding
O	0036462	biological_process	TRAIL-activated apoptotic signaling pathway
O	0042104	biological_process	positive regulation of activated T cell proliferation
O	0042220	biological_process	response to cocaine
O	0042802	molecular_function	identical protein binding
O	0043029	biological_process	T cell homeostasis
O	0043065	biological_process	positive regulation of apoptotic process
O	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
O	0044297	cellular_component	cell body
O	0044877	molecular_function	protein-containing complex binding
O	0045087	biological_process	innate immune response
O	0045089	biological_process	positive regulation of innate immune response
O	0045651	biological_process	positive regulation of macrophage differentiation
O	0045862	biological_process	positive regulation of proteolysis
O	0045944	biological_process	positive regulation of transcription by RNA polymerase II
O	0048148	biological_process	behavioral response to cocaine
O	0048535	biological_process	lymph node development
O	0048536	biological_process	spleen development
O	0048538	biological_process	thymus development
O	0050778	biological_process	positive regulation of immune response
O	0051607	biological_process	defense response to virus
O	0051707	biological_process	response to other organism
O	0060340	biological_process	positive regulation of type I interferon-mediated signaling pathway
O	0060544	biological_process	regulation of necroptotic process
O	0070236	biological_process	negative regulation of activation-induced cell death of T cells
O	0071260	biological_process	cellular response to mechanical stimulus
O	0071550	biological_process	death-inducing signaling complex assembly
O	0089720	molecular_function	caspase binding
O	0097190	biological_process	apoptotic signaling pathway
O	0097191	biological_process	extrinsic apoptotic signaling pathway
O	0097342	cellular_component	ripoptosome
O	0097527	biological_process	necroptotic signaling pathway
O	1900119	biological_process	positive regulation of execution phase of apoptosis
O	2000454	biological_process	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
O	2001238	biological_process	positive regulation of extrinsic apoptotic signaling pathway
P	0001819	biological_process	positive regulation of cytokine production
P	0001822	biological_process	kidney development
P	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
P	0002020	molecular_function	protease binding
P	0002376	biological_process	immune system process
P	0002821	biological_process	positive regulation of adaptive immune response
P	0005123	molecular_function	death receptor binding
P	0005164	molecular_function	tumor necrosis factor receptor binding
P	0005515	molecular_function	protein binding
P	0005654	cellular_component	nucleoplasm
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0005886	cellular_component	plasma membrane
P	0006915	biological_process	apoptotic process
P	0006952	biological_process	defense response
P	0008625	biological_process	extrinsic apoptotic signaling pathway via death domain receptors
P	0009898	cellular_component	cytoplasmic side of plasma membrane
P	0030674	molecular_function	protein-macromolecule adaptor activity
P	0031264	cellular_component	death-inducing signaling complex
P	0031265	cellular_component	CD95 death-inducing signaling complex
P	0032729	biological_process	positive regulation of type II interferon production
P	0032757	biological_process	positive regulation of interleukin-8 production
P	0032760	biological_process	positive regulation of tumor necrosis factor production
P	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
P	0032991	cellular_component	protein-containing complex
P	0033077	biological_process	T cell differentiation in thymus
P	0033612	molecular_function	receptor serine/threonine kinase binding
P	0035591	molecular_function	signaling adaptor activity
P	0035877	molecular_function	death effector domain binding
P	0036462	biological_process	TRAIL-activated apoptotic signaling pathway
P	0042104	biological_process	positive regulation of activated T cell proliferation
P	0042220	biological_process	response to cocaine
P	0042802	molecular_function	identical protein binding
P	0043029	biological_process	T cell homeostasis
P	0043065	biological_process	positive regulation of apoptotic process
P	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
P	0044297	cellular_component	cell body
P	0044877	molecular_function	protein-containing complex binding
P	0045087	biological_process	innate immune response
P	0045089	biological_process	positive regulation of innate immune response
P	0045651	biological_process	positive regulation of macrophage differentiation
P	0045862	biological_process	positive regulation of proteolysis
P	0045944	biological_process	positive regulation of transcription by RNA polymerase II
P	0048148	biological_process	behavioral response to cocaine
P	0048535	biological_process	lymph node development
P	0048536	biological_process	spleen development
P	0048538	biological_process	thymus development
P	0050778	biological_process	positive regulation of immune response
P	0051607	biological_process	defense response to virus
P	0051707	biological_process	response to other organism
P	0060340	biological_process	positive regulation of type I interferon-mediated signaling pathway
P	0060544	biological_process	regulation of necroptotic process
P	0070236	biological_process	negative regulation of activation-induced cell death of T cells
P	0071260	biological_process	cellular response to mechanical stimulus
P	0071550	biological_process	death-inducing signaling complex assembly
P	0089720	molecular_function	caspase binding
P	0097190	biological_process	apoptotic signaling pathway
P	0097191	biological_process	extrinsic apoptotic signaling pathway
P	0097342	cellular_component	ripoptosome
P	0097527	biological_process	necroptotic signaling pathway
P	1900119	biological_process	positive regulation of execution phase of apoptosis
P	2000454	biological_process	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
P	2001238	biological_process	positive regulation of extrinsic apoptotic signaling pathway
Q	0001819	biological_process	positive regulation of cytokine production
Q	0001822	biological_process	kidney development
Q	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
Q	0002020	molecular_function	protease binding
Q	0002376	biological_process	immune system process
Q	0002821	biological_process	positive regulation of adaptive immune response
Q	0005123	molecular_function	death receptor binding
Q	0005164	molecular_function	tumor necrosis factor receptor binding
Q	0005515	molecular_function	protein binding
Q	0005654	cellular_component	nucleoplasm
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0005886	cellular_component	plasma membrane
Q	0006915	biological_process	apoptotic process
Q	0006952	biological_process	defense response
Q	0008625	biological_process	extrinsic apoptotic signaling pathway via death domain receptors
Q	0009898	cellular_component	cytoplasmic side of plasma membrane
Q	0030674	molecular_function	protein-macromolecule adaptor activity
Q	0031264	cellular_component	death-inducing signaling complex
Q	0031265	cellular_component	CD95 death-inducing signaling complex
Q	0032729	biological_process	positive regulation of type II interferon production
Q	0032757	biological_process	positive regulation of interleukin-8 production
Q	0032760	biological_process	positive regulation of tumor necrosis factor production
Q	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
Q	0032991	cellular_component	protein-containing complex
Q	0033077	biological_process	T cell differentiation in thymus
Q	0033612	molecular_function	receptor serine/threonine kinase binding
Q	0035591	molecular_function	signaling adaptor activity
Q	0035877	molecular_function	death effector domain binding
Q	0036462	biological_process	TRAIL-activated apoptotic signaling pathway
Q	0042104	biological_process	positive regulation of activated T cell proliferation
Q	0042220	biological_process	response to cocaine
Q	0042802	molecular_function	identical protein binding
Q	0043029	biological_process	T cell homeostasis
Q	0043065	biological_process	positive regulation of apoptotic process
Q	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
Q	0044297	cellular_component	cell body
Q	0044877	molecular_function	protein-containing complex binding
Q	0045087	biological_process	innate immune response
Q	0045089	biological_process	positive regulation of innate immune response
Q	0045651	biological_process	positive regulation of macrophage differentiation
Q	0045862	biological_process	positive regulation of proteolysis
Q	0045944	biological_process	positive regulation of transcription by RNA polymerase II
Q	0048148	biological_process	behavioral response to cocaine
Q	0048535	biological_process	lymph node development
Q	0048536	biological_process	spleen development
Q	0048538	biological_process	thymus development
Q	0050778	biological_process	positive regulation of immune response
Q	0051607	biological_process	defense response to virus
Q	0051707	biological_process	response to other organism
Q	0060340	biological_process	positive regulation of type I interferon-mediated signaling pathway
Q	0060544	biological_process	regulation of necroptotic process
Q	0070236	biological_process	negative regulation of activation-induced cell death of T cells
Q	0071260	biological_process	cellular response to mechanical stimulus
Q	0071550	biological_process	death-inducing signaling complex assembly
Q	0089720	molecular_function	caspase binding
Q	0097190	biological_process	apoptotic signaling pathway
Q	0097191	biological_process	extrinsic apoptotic signaling pathway
Q	0097342	cellular_component	ripoptosome
Q	0097527	biological_process	necroptotic signaling pathway
Q	1900119	biological_process	positive regulation of execution phase of apoptosis
Q	2000454	biological_process	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
Q	2001238	biological_process	positive regulation of extrinsic apoptotic signaling pathway
R	0001819	biological_process	positive regulation of cytokine production
R	0001822	biological_process	kidney development
R	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
R	0002020	molecular_function	protease binding
R	0002376	biological_process	immune system process
R	0002821	biological_process	positive regulation of adaptive immune response
R	0005123	molecular_function	death receptor binding
R	0005164	molecular_function	tumor necrosis factor receptor binding
R	0005515	molecular_function	protein binding
R	0005654	cellular_component	nucleoplasm
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0005886	cellular_component	plasma membrane
R	0006915	biological_process	apoptotic process
R	0006952	biological_process	defense response
R	0008625	biological_process	extrinsic apoptotic signaling pathway via death domain receptors
R	0009898	cellular_component	cytoplasmic side of plasma membrane
R	0030674	molecular_function	protein-macromolecule adaptor activity
R	0031264	cellular_component	death-inducing signaling complex
R	0031265	cellular_component	CD95 death-inducing signaling complex
R	0032729	biological_process	positive regulation of type II interferon production
R	0032757	biological_process	positive regulation of interleukin-8 production
R	0032760	biological_process	positive regulation of tumor necrosis factor production
R	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
R	0032991	cellular_component	protein-containing complex
R	0033077	biological_process	T cell differentiation in thymus
R	0033612	molecular_function	receptor serine/threonine kinase binding
R	0035591	molecular_function	signaling adaptor activity
R	0035877	molecular_function	death effector domain binding
R	0036462	biological_process	TRAIL-activated apoptotic signaling pathway
R	0042104	biological_process	positive regulation of activated T cell proliferation
R	0042220	biological_process	response to cocaine
R	0042802	molecular_function	identical protein binding
R	0043029	biological_process	T cell homeostasis
R	0043065	biological_process	positive regulation of apoptotic process
R	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
R	0044297	cellular_component	cell body
R	0044877	molecular_function	protein-containing complex binding
R	0045087	biological_process	innate immune response
R	0045089	biological_process	positive regulation of innate immune response
R	0045651	biological_process	positive regulation of macrophage differentiation
R	0045862	biological_process	positive regulation of proteolysis
R	0045944	biological_process	positive regulation of transcription by RNA polymerase II
R	0048148	biological_process	behavioral response to cocaine
R	0048535	biological_process	lymph node development
R	0048536	biological_process	spleen development
R	0048538	biological_process	thymus development
R	0050778	biological_process	positive regulation of immune response
R	0051607	biological_process	defense response to virus
R	0051707	biological_process	response to other organism
R	0060340	biological_process	positive regulation of type I interferon-mediated signaling pathway
R	0060544	biological_process	regulation of necroptotic process
R	0070236	biological_process	negative regulation of activation-induced cell death of T cells
R	0071260	biological_process	cellular response to mechanical stimulus
R	0071550	biological_process	death-inducing signaling complex assembly
R	0089720	molecular_function	caspase binding
R	0097190	biological_process	apoptotic signaling pathway
R	0097191	biological_process	extrinsic apoptotic signaling pathway
R	0097342	cellular_component	ripoptosome
R	0097527	biological_process	necroptotic signaling pathway
R	1900119	biological_process	positive regulation of execution phase of apoptosis
R	2000454	biological_process	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
R	2001238	biological_process	positive regulation of extrinsic apoptotic signaling pathway
S	0001819	biological_process	positive regulation of cytokine production
S	0001822	biological_process	kidney development
S	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
S	0002020	molecular_function	protease binding
S	0002376	biological_process	immune system process
S	0002821	biological_process	positive regulation of adaptive immune response
S	0005123	molecular_function	death receptor binding
S	0005164	molecular_function	tumor necrosis factor receptor binding
S	0005515	molecular_function	protein binding
S	0005654	cellular_component	nucleoplasm
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0005886	cellular_component	plasma membrane
S	0006915	biological_process	apoptotic process
S	0006952	biological_process	defense response
S	0008625	biological_process	extrinsic apoptotic signaling pathway via death domain receptors
S	0009898	cellular_component	cytoplasmic side of plasma membrane
S	0030674	molecular_function	protein-macromolecule adaptor activity
S	0031264	cellular_component	death-inducing signaling complex
S	0031265	cellular_component	CD95 death-inducing signaling complex
S	0032729	biological_process	positive regulation of type II interferon production
S	0032757	biological_process	positive regulation of interleukin-8 production
S	0032760	biological_process	positive regulation of tumor necrosis factor production
S	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
S	0032991	cellular_component	protein-containing complex
S	0033077	biological_process	T cell differentiation in thymus
S	0033612	molecular_function	receptor serine/threonine kinase binding
S	0035591	molecular_function	signaling adaptor activity
S	0035877	molecular_function	death effector domain binding
S	0036462	biological_process	TRAIL-activated apoptotic signaling pathway
S	0042104	biological_process	positive regulation of activated T cell proliferation
S	0042220	biological_process	response to cocaine
S	0042802	molecular_function	identical protein binding
S	0043029	biological_process	T cell homeostasis
S	0043065	biological_process	positive regulation of apoptotic process
S	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
S	0044297	cellular_component	cell body
S	0044877	molecular_function	protein-containing complex binding
S	0045087	biological_process	innate immune response
S	0045089	biological_process	positive regulation of innate immune response
S	0045651	biological_process	positive regulation of macrophage differentiation
S	0045862	biological_process	positive regulation of proteolysis
S	0045944	biological_process	positive regulation of transcription by RNA polymerase II
S	0048148	biological_process	behavioral response to cocaine
S	0048535	biological_process	lymph node development
S	0048536	biological_process	spleen development
S	0048538	biological_process	thymus development
S	0050778	biological_process	positive regulation of immune response
S	0051607	biological_process	defense response to virus
S	0051707	biological_process	response to other organism
S	0060340	biological_process	positive regulation of type I interferon-mediated signaling pathway
S	0060544	biological_process	regulation of necroptotic process
S	0070236	biological_process	negative regulation of activation-induced cell death of T cells
S	0071260	biological_process	cellular response to mechanical stimulus
S	0071550	biological_process	death-inducing signaling complex assembly
S	0089720	molecular_function	caspase binding
S	0097190	biological_process	apoptotic signaling pathway
S	0097191	biological_process	extrinsic apoptotic signaling pathway
S	0097342	cellular_component	ripoptosome
S	0097527	biological_process	necroptotic signaling pathway
S	1900119	biological_process	positive regulation of execution phase of apoptosis
S	2000454	biological_process	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
S	2001238	biological_process	positive regulation of extrinsic apoptotic signaling pathway
T	0001819	biological_process	positive regulation of cytokine production
T	0001822	biological_process	kidney development
T	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
T	0002020	molecular_function	protease binding
T	0002376	biological_process	immune system process
T	0002821	biological_process	positive regulation of adaptive immune response
T	0005123	molecular_function	death receptor binding
T	0005164	molecular_function	tumor necrosis factor receptor binding
T	0005515	molecular_function	protein binding
T	0005654	cellular_component	nucleoplasm
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0005886	cellular_component	plasma membrane
T	0006915	biological_process	apoptotic process
T	0006952	biological_process	defense response
T	0008625	biological_process	extrinsic apoptotic signaling pathway via death domain receptors
T	0009898	cellular_component	cytoplasmic side of plasma membrane
T	0030674	molecular_function	protein-macromolecule adaptor activity
T	0031264	cellular_component	death-inducing signaling complex
T	0031265	cellular_component	CD95 death-inducing signaling complex
T	0032729	biological_process	positive regulation of type II interferon production
T	0032757	biological_process	positive regulation of interleukin-8 production
T	0032760	biological_process	positive regulation of tumor necrosis factor production
T	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
T	0032991	cellular_component	protein-containing complex
T	0033077	biological_process	T cell differentiation in thymus
T	0033612	molecular_function	receptor serine/threonine kinase binding
T	0035591	molecular_function	signaling adaptor activity
T	0035877	molecular_function	death effector domain binding
T	0036462	biological_process	TRAIL-activated apoptotic signaling pathway
T	0042104	biological_process	positive regulation of activated T cell proliferation
T	0042220	biological_process	response to cocaine
T	0042802	molecular_function	identical protein binding
T	0043029	biological_process	T cell homeostasis
T	0043065	biological_process	positive regulation of apoptotic process
T	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
T	0044297	cellular_component	cell body
T	0044877	molecular_function	protein-containing complex binding
T	0045087	biological_process	innate immune response
T	0045089	biological_process	positive regulation of innate immune response
T	0045651	biological_process	positive regulation of macrophage differentiation
T	0045862	biological_process	positive regulation of proteolysis
T	0045944	biological_process	positive regulation of transcription by RNA polymerase II
T	0048148	biological_process	behavioral response to cocaine
T	0048535	biological_process	lymph node development
T	0048536	biological_process	spleen development
T	0048538	biological_process	thymus development
T	0050778	biological_process	positive regulation of immune response
T	0051607	biological_process	defense response to virus
T	0051707	biological_process	response to other organism
T	0060340	biological_process	positive regulation of type I interferon-mediated signaling pathway
T	0060544	biological_process	regulation of necroptotic process
T	0070236	biological_process	negative regulation of activation-induced cell death of T cells
T	0071260	biological_process	cellular response to mechanical stimulus
T	0071550	biological_process	death-inducing signaling complex assembly
T	0089720	molecular_function	caspase binding
T	0097190	biological_process	apoptotic signaling pathway
T	0097191	biological_process	extrinsic apoptotic signaling pathway
T	0097342	cellular_component	ripoptosome
T	0097527	biological_process	necroptotic signaling pathway
T	1900119	biological_process	positive regulation of execution phase of apoptosis
T	2000454	biological_process	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
T	2001238	biological_process	positive regulation of extrinsic apoptotic signaling pathway
U	0001819	biological_process	positive regulation of cytokine production
U	0001822	biological_process	kidney development
U	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
U	0002020	molecular_function	protease binding
U	0002376	biological_process	immune system process
U	0002821	biological_process	positive regulation of adaptive immune response
U	0005123	molecular_function	death receptor binding
U	0005164	molecular_function	tumor necrosis factor receptor binding
U	0005515	molecular_function	protein binding
U	0005654	cellular_component	nucleoplasm
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0005886	cellular_component	plasma membrane
U	0006915	biological_process	apoptotic process
U	0006952	biological_process	defense response
U	0008625	biological_process	extrinsic apoptotic signaling pathway via death domain receptors
U	0009898	cellular_component	cytoplasmic side of plasma membrane
U	0030674	molecular_function	protein-macromolecule adaptor activity
U	0031264	cellular_component	death-inducing signaling complex
U	0031265	cellular_component	CD95 death-inducing signaling complex
U	0032729	biological_process	positive regulation of type II interferon production
U	0032757	biological_process	positive regulation of interleukin-8 production
U	0032760	biological_process	positive regulation of tumor necrosis factor production
U	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
U	0032991	cellular_component	protein-containing complex
U	0033077	biological_process	T cell differentiation in thymus
U	0033612	molecular_function	receptor serine/threonine kinase binding
U	0035591	molecular_function	signaling adaptor activity
U	0035877	molecular_function	death effector domain binding
U	0036462	biological_process	TRAIL-activated apoptotic signaling pathway
U	0042104	biological_process	positive regulation of activated T cell proliferation
U	0042220	biological_process	response to cocaine
U	0042802	molecular_function	identical protein binding
U	0043029	biological_process	T cell homeostasis
U	0043065	biological_process	positive regulation of apoptotic process
U	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
U	0044297	cellular_component	cell body
U	0044877	molecular_function	protein-containing complex binding
U	0045087	biological_process	innate immune response
U	0045089	biological_process	positive regulation of innate immune response
U	0045651	biological_process	positive regulation of macrophage differentiation
U	0045862	biological_process	positive regulation of proteolysis
U	0045944	biological_process	positive regulation of transcription by RNA polymerase II
U	0048148	biological_process	behavioral response to cocaine
U	0048535	biological_process	lymph node development
U	0048536	biological_process	spleen development
U	0048538	biological_process	thymus development
U	0050778	biological_process	positive regulation of immune response
U	0051607	biological_process	defense response to virus
U	0051707	biological_process	response to other organism
U	0060340	biological_process	positive regulation of type I interferon-mediated signaling pathway
U	0060544	biological_process	regulation of necroptotic process
U	0070236	biological_process	negative regulation of activation-induced cell death of T cells
U	0071260	biological_process	cellular response to mechanical stimulus
U	0071550	biological_process	death-inducing signaling complex assembly
U	0089720	molecular_function	caspase binding
U	0097190	biological_process	apoptotic signaling pathway
U	0097191	biological_process	extrinsic apoptotic signaling pathway
U	0097342	cellular_component	ripoptosome
U	0097527	biological_process	necroptotic signaling pathway
U	1900119	biological_process	positive regulation of execution phase of apoptosis
U	2000454	biological_process	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
U	2001238	biological_process	positive regulation of extrinsic apoptotic signaling pathway
V	0001819	biological_process	positive regulation of cytokine production
V	0001822	biological_process	kidney development
V	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
V	0002020	molecular_function	protease binding
V	0002376	biological_process	immune system process
V	0002821	biological_process	positive regulation of adaptive immune response
V	0005123	molecular_function	death receptor binding
V	0005164	molecular_function	tumor necrosis factor receptor binding
V	0005515	molecular_function	protein binding
V	0005654	cellular_component	nucleoplasm
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0005886	cellular_component	plasma membrane
V	0006915	biological_process	apoptotic process
V	0006952	biological_process	defense response
V	0008625	biological_process	extrinsic apoptotic signaling pathway via death domain receptors
V	0009898	cellular_component	cytoplasmic side of plasma membrane
V	0030674	molecular_function	protein-macromolecule adaptor activity
V	0031264	cellular_component	death-inducing signaling complex
V	0031265	cellular_component	CD95 death-inducing signaling complex
V	0032729	biological_process	positive regulation of type II interferon production
V	0032757	biological_process	positive regulation of interleukin-8 production
V	0032760	biological_process	positive regulation of tumor necrosis factor production
V	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
V	0032991	cellular_component	protein-containing complex
V	0033077	biological_process	T cell differentiation in thymus
V	0033612	molecular_function	receptor serine/threonine kinase binding
V	0035591	molecular_function	signaling adaptor activity
V	0035877	molecular_function	death effector domain binding
V	0036462	biological_process	TRAIL-activated apoptotic signaling pathway
V	0042104	biological_process	positive regulation of activated T cell proliferation
V	0042220	biological_process	response to cocaine
V	0042802	molecular_function	identical protein binding
V	0043029	biological_process	T cell homeostasis
V	0043065	biological_process	positive regulation of apoptotic process
V	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
V	0044297	cellular_component	cell body
V	0044877	molecular_function	protein-containing complex binding
V	0045087	biological_process	innate immune response
V	0045089	biological_process	positive regulation of innate immune response
V	0045651	biological_process	positive regulation of macrophage differentiation
V	0045862	biological_process	positive regulation of proteolysis
V	0045944	biological_process	positive regulation of transcription by RNA polymerase II
V	0048148	biological_process	behavioral response to cocaine
V	0048535	biological_process	lymph node development
V	0048536	biological_process	spleen development
V	0048538	biological_process	thymus development
V	0050778	biological_process	positive regulation of immune response
V	0051607	biological_process	defense response to virus
V	0051707	biological_process	response to other organism
V	0060340	biological_process	positive regulation of type I interferon-mediated signaling pathway
V	0060544	biological_process	regulation of necroptotic process
V	0070236	biological_process	negative regulation of activation-induced cell death of T cells
V	0071260	biological_process	cellular response to mechanical stimulus
V	0071550	biological_process	death-inducing signaling complex assembly
V	0089720	molecular_function	caspase binding
V	0097190	biological_process	apoptotic signaling pathway
V	0097191	biological_process	extrinsic apoptotic signaling pathway
V	0097342	cellular_component	ripoptosome
V	0097527	biological_process	necroptotic signaling pathway
V	1900119	biological_process	positive regulation of execution phase of apoptosis
V	2000454	biological_process	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
V	2001238	biological_process	positive regulation of extrinsic apoptotic signaling pathway
W	0001819	biological_process	positive regulation of cytokine production
W	0001822	biological_process	kidney development
W	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
W	0002020	molecular_function	protease binding
W	0002376	biological_process	immune system process
W	0002821	biological_process	positive regulation of adaptive immune response
W	0005123	molecular_function	death receptor binding
W	0005164	molecular_function	tumor necrosis factor receptor binding
W	0005515	molecular_function	protein binding
W	0005654	cellular_component	nucleoplasm
W	0005737	cellular_component	cytoplasm
W	0005829	cellular_component	cytosol
W	0005886	cellular_component	plasma membrane
W	0006915	biological_process	apoptotic process
W	0006952	biological_process	defense response
W	0008625	biological_process	extrinsic apoptotic signaling pathway via death domain receptors
W	0009898	cellular_component	cytoplasmic side of plasma membrane
W	0030674	molecular_function	protein-macromolecule adaptor activity
W	0031264	cellular_component	death-inducing signaling complex
W	0031265	cellular_component	CD95 death-inducing signaling complex
W	0032729	biological_process	positive regulation of type II interferon production
W	0032757	biological_process	positive regulation of interleukin-8 production
W	0032760	biological_process	positive regulation of tumor necrosis factor production
W	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
W	0032991	cellular_component	protein-containing complex
W	0033077	biological_process	T cell differentiation in thymus
W	0033612	molecular_function	receptor serine/threonine kinase binding
W	0035591	molecular_function	signaling adaptor activity
W	0035877	molecular_function	death effector domain binding
W	0036462	biological_process	TRAIL-activated apoptotic signaling pathway
W	0042104	biological_process	positive regulation of activated T cell proliferation
W	0042220	biological_process	response to cocaine
W	0042802	molecular_function	identical protein binding
W	0043029	biological_process	T cell homeostasis
W	0043065	biological_process	positive regulation of apoptotic process
W	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
W	0044297	cellular_component	cell body
W	0044877	molecular_function	protein-containing complex binding
W	0045087	biological_process	innate immune response
W	0045089	biological_process	positive regulation of innate immune response
W	0045651	biological_process	positive regulation of macrophage differentiation
W	0045862	biological_process	positive regulation of proteolysis
W	0045944	biological_process	positive regulation of transcription by RNA polymerase II
W	0048148	biological_process	behavioral response to cocaine
W	0048535	biological_process	lymph node development
W	0048536	biological_process	spleen development
W	0048538	biological_process	thymus development
W	0050778	biological_process	positive regulation of immune response
W	0051607	biological_process	defense response to virus
W	0051707	biological_process	response to other organism
W	0060340	biological_process	positive regulation of type I interferon-mediated signaling pathway
W	0060544	biological_process	regulation of necroptotic process
W	0070236	biological_process	negative regulation of activation-induced cell death of T cells
W	0071260	biological_process	cellular response to mechanical stimulus
W	0071550	biological_process	death-inducing signaling complex assembly
W	0089720	molecular_function	caspase binding
W	0097190	biological_process	apoptotic signaling pathway
W	0097191	biological_process	extrinsic apoptotic signaling pathway
W	0097342	cellular_component	ripoptosome
W	0097527	biological_process	necroptotic signaling pathway
W	1900119	biological_process	positive regulation of execution phase of apoptosis
W	2000454	biological_process	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
W	2001238	biological_process	positive regulation of extrinsic apoptotic signaling pathway
X	0001819	biological_process	positive regulation of cytokine production
X	0001822	biological_process	kidney development
X	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
X	0002020	molecular_function	protease binding
X	0002376	biological_process	immune system process
X	0002821	biological_process	positive regulation of adaptive immune response
X	0005123	molecular_function	death receptor binding
X	0005164	molecular_function	tumor necrosis factor receptor binding
X	0005515	molecular_function	protein binding
X	0005654	cellular_component	nucleoplasm
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0005886	cellular_component	plasma membrane
X	0006915	biological_process	apoptotic process
X	0006952	biological_process	defense response
X	0008625	biological_process	extrinsic apoptotic signaling pathway via death domain receptors
X	0009898	cellular_component	cytoplasmic side of plasma membrane
X	0030674	molecular_function	protein-macromolecule adaptor activity
X	0031264	cellular_component	death-inducing signaling complex
X	0031265	cellular_component	CD95 death-inducing signaling complex
X	0032729	biological_process	positive regulation of type II interferon production
X	0032757	biological_process	positive regulation of interleukin-8 production
X	0032760	biological_process	positive regulation of tumor necrosis factor production
X	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
X	0032991	cellular_component	protein-containing complex
X	0033077	biological_process	T cell differentiation in thymus
X	0033612	molecular_function	receptor serine/threonine kinase binding
X	0035591	molecular_function	signaling adaptor activity
X	0035877	molecular_function	death effector domain binding
X	0036462	biological_process	TRAIL-activated apoptotic signaling pathway
X	0042104	biological_process	positive regulation of activated T cell proliferation
X	0042220	biological_process	response to cocaine
X	0042802	molecular_function	identical protein binding
X	0043029	biological_process	T cell homeostasis
X	0043065	biological_process	positive regulation of apoptotic process
X	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
X	0044297	cellular_component	cell body
X	0044877	molecular_function	protein-containing complex binding
X	0045087	biological_process	innate immune response
X	0045089	biological_process	positive regulation of innate immune response
X	0045651	biological_process	positive regulation of macrophage differentiation
X	0045862	biological_process	positive regulation of proteolysis
X	0045944	biological_process	positive regulation of transcription by RNA polymerase II
X	0048148	biological_process	behavioral response to cocaine
X	0048535	biological_process	lymph node development
X	0048536	biological_process	spleen development
X	0048538	biological_process	thymus development
X	0050778	biological_process	positive regulation of immune response
X	0051607	biological_process	defense response to virus
X	0051707	biological_process	response to other organism
X	0060340	biological_process	positive regulation of type I interferon-mediated signaling pathway
X	0060544	biological_process	regulation of necroptotic process
X	0070236	biological_process	negative regulation of activation-induced cell death of T cells
X	0071260	biological_process	cellular response to mechanical stimulus
X	0071550	biological_process	death-inducing signaling complex assembly
X	0089720	molecular_function	caspase binding
X	0097190	biological_process	apoptotic signaling pathway
X	0097191	biological_process	extrinsic apoptotic signaling pathway
X	0097342	cellular_component	ripoptosome
X	0097527	biological_process	necroptotic signaling pathway
X	1900119	biological_process	positive regulation of execution phase of apoptosis
X	2000454	biological_process	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
X	2001238	biological_process	positive regulation of extrinsic apoptotic signaling pathway
Y	0001819	biological_process	positive regulation of cytokine production
Y	0001822	biological_process	kidney development
Y	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
Y	0002020	molecular_function	protease binding
Y	0002376	biological_process	immune system process
Y	0002821	biological_process	positive regulation of adaptive immune response
Y	0005123	molecular_function	death receptor binding
Y	0005164	molecular_function	tumor necrosis factor receptor binding
Y	0005515	molecular_function	protein binding
Y	0005654	cellular_component	nucleoplasm
Y	0005737	cellular_component	cytoplasm
Y	0005829	cellular_component	cytosol
Y	0005886	cellular_component	plasma membrane
Y	0006915	biological_process	apoptotic process
Y	0006952	biological_process	defense response
Y	0008625	biological_process	extrinsic apoptotic signaling pathway via death domain receptors
Y	0009898	cellular_component	cytoplasmic side of plasma membrane
Y	0030674	molecular_function	protein-macromolecule adaptor activity
Y	0031264	cellular_component	death-inducing signaling complex
Y	0031265	cellular_component	CD95 death-inducing signaling complex
Y	0032729	biological_process	positive regulation of type II interferon production
Y	0032757	biological_process	positive regulation of interleukin-8 production
Y	0032760	biological_process	positive regulation of tumor necrosis factor production
Y	0032813	molecular_function	tumor necrosis factor receptor superfamily binding
Y	0032991	cellular_component	protein-containing complex
Y	0033077	biological_process	T cell differentiation in thymus
Y	0033612	molecular_function	receptor serine/threonine kinase binding
Y	0035591	molecular_function	signaling adaptor activity
Y	0035877	molecular_function	death effector domain binding
Y	0036462	biological_process	TRAIL-activated apoptotic signaling pathway
Y	0042104	biological_process	positive regulation of activated T cell proliferation
Y	0042220	biological_process	response to cocaine
Y	0042802	molecular_function	identical protein binding
Y	0043029	biological_process	T cell homeostasis
Y	0043065	biological_process	positive regulation of apoptotic process
Y	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
Y	0044297	cellular_component	cell body
Y	0044877	molecular_function	protein-containing complex binding
Y	0045087	biological_process	innate immune response
Y	0045089	biological_process	positive regulation of innate immune response
Y	0045651	biological_process	positive regulation of macrophage differentiation
Y	0045862	biological_process	positive regulation of proteolysis
Y	0045944	biological_process	positive regulation of transcription by RNA polymerase II
Y	0048148	biological_process	behavioral response to cocaine
Y	0048535	biological_process	lymph node development
Y	0048536	biological_process	spleen development
Y	0048538	biological_process	thymus development
Y	0050778	biological_process	positive regulation of immune response
Y	0051607	biological_process	defense response to virus
Y	0051707	biological_process	response to other organism
Y	0060340	biological_process	positive regulation of type I interferon-mediated signaling pathway
Y	0060544	biological_process	regulation of necroptotic process
Y	0070236	biological_process	negative regulation of activation-induced cell death of T cells
Y	0071260	biological_process	cellular response to mechanical stimulus
Y	0071550	biological_process	death-inducing signaling complex assembly
Y	0089720	molecular_function	caspase binding
Y	0097190	biological_process	apoptotic signaling pathway
Y	0097191	biological_process	extrinsic apoptotic signaling pathway
Y	0097342	cellular_component	ripoptosome
Y	0097527	biological_process	necroptotic signaling pathway
Y	1900119	biological_process	positive regulation of execution phase of apoptosis
Y	2000454	biological_process	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
Y	2001238	biological_process	positive regulation of extrinsic apoptotic signaling pathway

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1872
Details	Domain: {"description":"DED","evidences":[{"source":"PROSITE-ProRule","id":"PRU00065","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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