9T1S

Heterodisulfide-Hydrogenase-Formate Dehydrogenase dimer

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0005886	cellular_component	plasma membrane
E	0016491	molecular_function	oxidoreductase activity
F	0005886	cellular_component	plasma membrane
F	0016491	molecular_function	oxidoreductase activity
G	0047985	molecular_function	hydrogen dehydrogenase activity
L	0003954	molecular_function	NADH dehydrogenase activity
L	0016020	cellular_component	membrane
L	0016725	molecular_function	oxidoreductase activity, acting on CH or CH2 groups
L	0022904	biological_process	respiratory electron transport chain
L	0043794	molecular_function	formate dehydrogenase (coenzyme F420) activity
L	0051539	molecular_function	4 iron, 4 sulfur cluster binding

Functional Information from PROSITE/UniProt

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CyQCGtCTgSCP

Chain	Residue	Details
E	CYS34-PRO45
E	CYS77-PRO88
A	CYS246-PRO257
A	CYS584-PRO595
A	CYS617-PRO628
M	CYS286-PRO297
M	CYS335-PRO346

---

site_id	PS00490
Number of Residues	18
Details	MOLYBDOPTERIN_PROK_2 Prokaryotic molybdopterin oxidoreductases signature 2. TeTAqvADVVLPgASwaE

Chain	Residue	Details
L	THR421-GLU438

---

site_id	PS00507
Number of Residues	26
Details	NI_HGENASE_L_1 Nickel-dependent hydrogenases large subunit signature 1. RGFEqfvvgrpaeevprivPRiCGIC

Chain	Residue	Details
G	ARG39-CYS64

---

site_id	PS00551
Number of Residues	18
Details	MOLYBDOPTERIN_PROK_1 Prokaryotic molybdopterin oxidoreductases signature 1. TiCpy.CGTgCgVdLvvk.D

Chain	Residue	Details
L	THR8-ASP25

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	60
Details	Domain: {"description":"4Fe-4S ferredoxin-type 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00711","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	64
Details	Domain: {"description":"4Fe-4S ferredoxin-type 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00711","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00711","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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